Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Mojca Frank-Bertoncelj"'
Autor:
Xiangyu Ge, Mojca Frank-Bertoncelj, Kerstin Klein, Amanda McGovern, Tadeja Kuret, Miranda Houtman, Blaž Burja, Raphael Micheroli, Chenfu Shi, Miriam Marks, Andrew Filer, Christopher D. Buckley, Gisela Orozco, Oliver Distler, Andrew P. Morris, Paul Martin, Stephen Eyre, Caroline Ospelt
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-39 (2021)
Abstract Background Genome-wide association studies have reported more than 100 risk loci for rheumatoid arthritis (RA). These loci are shown to be enriched in immune cell-specific enhancers, but the analysis so far has excluded stromal cells, such a
Externí odkaz:
https://doaj.org/article/8cd52096d8e14ee7b73e6f6f9def48f2
Autor:
Blaž Burja, Dominique Paul, Aizhan Tastanova, Sam G. Edalat, Reto Gerber, Miranda Houtman, Muriel Elhai, Kristina Bürki, Ramon Staeger, Gaetana Restivo, Ramon Lang, Snezna Sodin-Semrl, Katja Lakota, Matija Tomšič, Mitchell P. Levesque, Oliver Distler, Žiga Rotar, Mark D. Robinson, Mojca Frank-Bertoncelj
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
We present an optimized dissociation protocol for preparing high-quality skin cell suspensions for in-depth single-cell RNA-sequencing (scRNA-seq) analysis of fresh and cultured human skin. Our protocol enabled the isolation of a consistently high nu
Externí odkaz:
https://doaj.org/article/01090ad745fd47fcba51ae5ab9d51cbc
Autor:
Tadeja Kuret, Mojca Frank-Bertoncelj, Katja Lakota, Polona Žigon, Gerhard G. Thallinger, Andreja N. Kopitar, Saša Čučnik, Matija Tomšič, Alojzija Hočevar, Snežna Sodin-Šemrl
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
In the present study, we longitudinally monitored leukocyte subsets, expression of neutrophil surface adhesion molecules (CD62L and CD11b) and serum analytes in therapy-naïve patients with active giant cell arteritis (GCA). We collected blood sample
Externí odkaz:
https://doaj.org/article/c757a706849b4cee9bb1dfb36d60f763
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
The Janus kinase (JAK)—Signal transducer and activator of transcription (STAT) pathway is one of the central signaling hubs in inflammatory, immune and cancer cells. Inhibiting the JAK-STAT pathway with JAK inhibitors (jakinibs) constitutes an impo
Externí odkaz:
https://doaj.org/article/5e6d18cec0d84537b434732a56798842
Autor:
Mojca Frank-Bertoncelj, Michelle Trenkmann, Kerstin Klein, Emmanuel Karouzakis, Hubert Rehrauer, Anna Bratus, Christoph Kolling, Maria Armaka, Andrew Filer, Beat A. Michel, Renate E. Gay, Christopher D. Buckley, George Kollias, Steffen Gay, Caroline Ospelt
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Arthritis affects different joints variably despite systemic inflammatory cues. Here the authors show anatomical differences in the transcriptome, epigenome and function of synovial fibroblasts that might affect susceptibility to site-specific joint
Externí odkaz:
https://doaj.org/article/316497af76764c49b96164a02648272a
Autor:
Blaž Burja, Tadeja Kuret, Tea Janko, Dijana Topalović, Lada Živković, Katjuša Mrak-Poljšak, Biljana Spremo-Potparević, Polona Žigon, Oliver Distler, Saša Čučnik, Snezna Sodin-Semrl, Katja Lakota, Mojca Frank-Bertoncelj
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Olive leaf extract (OLE) is used in traditional medicine as a food supplement and as an over-the-counter drug for a variety of its effects, including anti-inflammatory and anti-atherosclerotic ones. Mechanisms through which OLE could modulate these p
Externí odkaz:
https://doaj.org/article/94cbd153d9564cc2ac5955756e7c7d68
Autor:
Miki Takata, Elena Pachera, Mojca Frank-Bertoncelj, Anastasiia Kozlova, Astrid Jüngel, Michael L. Whitfield, Shervin Assassi, Maurizio Calcagni, Jeska de Vries-Bouwstra, Tom W. Huizinga, Fina Kurreeman, Gabriela Kania, Oliver Distler
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Antisense long non-coding RNAs (AS lncRNAs) have increasingly been recognized as important regulators of gene expression and they have been found to play key roles in several diseases. However, very little is known about the role of AS lncRNAs in fib
Externí odkaz:
https://doaj.org/article/e06c1aa8a24045d9bc440cd601460014
Autor:
Ula Štok, Elizabeta Blokar, Metka Lenassi, Marija Holcar, Mojca Frank-Bertoncelj, Andreja Erman, Nataša Resnik, Snežna Sodin-Šemrl, Saša Čučnik, Katja Perdan Pirkmajer, Aleš Ambrožič, Polona Žigon
Publikováno v:
Cells, Vol 9, Iss 5, p 1211 (2020)
Antiphospholipid syndrome (APS) is a systemic autoimmune disease, characterized by thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL), which drive endothelial injury and thrombophilia. Extracellular vesicles (EV
Externí odkaz:
https://doaj.org/article/530ce4a21c684e30abfcb6af43546012
Autor:
Mojca Frank-Bertoncelj, David S. Pisetsky, Christoph Kolling, Beat A. Michel, Renate E. Gay, Astrid Jüngel, Steffen Gay
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Extracellular vesicles (EV) can modulate the responses of cells to toll-like receptor (TLR) ligation; conversely, TLR ligands such as double-stranded RNA (dsRNA) can enhance the release of EV and influence of the composition and functions of EV cargo
Externí odkaz:
https://doaj.org/article/0314900961ba490ab0d1dc3ea1b190ce
Autor:
Lenka Pleštilová, Michel Neidhart, Giancarlo Russo, Mojca Frank-Bertoncelj, Caroline Ospelt, Adrian Ciurea, Christoph Kolling, Renate E Gay, Beat A Michel, Jiří Vencovský, Steffen Gay, Astrid Jüngel
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166920 (2016)
The PIWIL (P-element induced wimpy testis like protein) subfamily of argonaute proteins is essential for Piwi-interacting RNA (piRNA) biogenesis and their function to silence transposons during germ-line development. Here we explored their presence a
Externí odkaz:
https://doaj.org/article/2c8778951b8e4a6fa92a1b24fc50c85f