Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Mojca Benčina"'
Autor:
Filip Ivanovski, Maja Meško, Tina Lebar, Marko Rupnik, Duško Lainšček, Miha Gradišek, Roman Jerala, Mojca Benčina
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Remote regulation of cells in deep tissue remains a significant challenge. Low-intensity pulsed ultrasound offers promise for in vivo therapies due to its non-invasive nature and precise control. This study uses pulsed ultrasound to control
Externí odkaz:
https://doaj.org/article/9d48a036c1904a118e2e8b6c9aa92ff9
Autor:
Tjaša Plaper, Estera Merljak, Tina Fink, Tadej Satler, Ajasja Ljubetič, Duško Lainšček, Vid Jazbec, Mojca Benčina, Sintija Stevanoska, Sašo Džeroski, Roman Jerala
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The regulation of protein function by external or internal signals is one of the key features of living organisms. The ability to directly control the function of a selected protein would represent a valuable tool for regulating biological p
Externí odkaz:
https://doaj.org/article/710274972bba4f1d86afcb8ef980b686
Autor:
Duško Lainšček, Vida Forstnerič, Veronika Mikolič, Špela Malenšek, Peter Pečan, Mojca Benčina, Matjaž Sever, Helena Podgornik, Roman Jerala
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The CRISPR/Cas system has emerged as a powerful and versatile genome engineering tool. Here the authors couple Cas9 to effector protein Exonuclease III via coiled-coil mediated interactions, termed CCExo, leading to increased deletion sizes and enhan
Externí odkaz:
https://doaj.org/article/f7179363155344cf811fce7648c9fef4
Autor:
Arne Praznik, Tina Fink, Nik Franko, Jan Lonzarić, Mojca Benčina, Nina Jerala, Tjaša Plaper, Samo Roškar, Roman Jerala
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Here the authors present two genetically encoded orthogonal regulatory secretion systems that enables inducible protein release and construction of logic
Externí odkaz:
https://doaj.org/article/ef2d00598be6446eafe33017bd693412
Autor:
Tjaša Plaper, Jana Aupič, Petra Dekleva, Fabio Lapenta, Mateja Manček Keber, Roman Jerala, Mojca Benčina
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Coiled-coil (CC) dimer-forming peptides are attractive designable modules for mediating protein association. Highly stable CCs are desired for biological activity regulation and assay. Here, we report the design and versatile applications of
Externí odkaz:
https://doaj.org/article/24366d44f44440bd9d30fddabfebcaae
Autor:
Tea Romih, Nikola Tasić, Lea Bibič, Ajda Beltram, Ika Fazarinc, Mojca Benčina, Roman Jerala, Samo B. Hočevar
Publikováno v:
Chemosensors, Vol 11, Iss 4, p 222 (2023)
The emergence of the SARS-CoV-2 virus and the associated pandemic has affected the entire human population. Human susceptibility to the virus has highlighted a tremendous need for affordable diagnostic systems to manage the pandemic and monitor the e
Externí odkaz:
https://doaj.org/article/86a849fc230545f08772068cb6e212a6
Autor:
Tina Fink, Bojana Stevović, René Verwaal, Johannes A. Roubos, Rok Gaber, Mojca Benčina, Roman Jerala, Helena Gradišar
Publikováno v:
AMB Express, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract The clustering of biosynthetic enzymes is used in nature to channel reaction products and increase the yield of compounds produced by multiple reaction steps. The coupling of multiple enzymes has been shown to increase the biosynthetic produ
Externí odkaz:
https://doaj.org/article/eafc2fc0d72845db91f1a302bce6ded8
Autor:
Eva Rajh, Tina Šket, Arne Praznik, Petra Sušjan, Alenka Šmid, Dunja Urbančič, Irena Mlinarič-Raščan, Polona Kogovšek, Tina Demšar, Mojca Milavec, Katarina Prosenc Trilar, Žiga Jensterle, Mihaela Zidarn, Viktorija Tomič, Gabriele Turel, Tatjana Lejko-Zupanc, Roman Jerala, Mojca Benčina
Publikováno v:
Molecules, Vol 26, Iss 21, p 6617 (2021)
Early diagnosis with rapid detection of the virus plays a key role in preventing the spread of infection and in treating patients effectively. In order to address the need for a straightforward detection of SARS-CoV-2 infection and assessment of vira
Externí odkaz:
https://doaj.org/article/42c6d2b103974f368a8c657759dd6512
Autor:
Jelka Pohar, Duško Lainšček, Karolina Ivičak-Kocjan, Miša-Mojca Cajnko, Roman Jerala, Mojca Benčina
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
DNA degradation products are frequently found in the endosome, but how they regulate the activation of Toll-like receptors is not known. Here the authors show that single-stranded DNA as short as two nucleotides can enhance the ability of longer DNA
Externí odkaz:
https://doaj.org/article/1d1c1bb6f0ba4562a591522915e4394a
Autor:
Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno E. Correia, David Peterhoff, Ralf Wagner, Valter Bergant, Alexander Herrmann, Andreas Pichlmair, Roman Jerala
Publikováno v:
Vaccines, Vol 9, Iss 5, p 431 (2021)
The response of the adaptive immune system is augmented by multimeric presentation of a specific antigen, resembling viral particles. Several vaccines have been designed based on natural or designed protein scaffolds, which exhibited a potent adaptiv
Externí odkaz:
https://doaj.org/article/74784734a4764cf7add9be42d5336cc7