Metastatic Breast Tumour Regression Following Treatment by a Gene-Modified Vaccinia Virus Expressing MUC1 and IL-2

Autor: David Miles, Martine Baudin, S. Van Belle, B. Uzielly, Philippe Beuzeboc, Moira Shearer, Patrick Squiban, Silvia von Mensdorff-Pouilly, Joyce Taylor-Papadimitriou, Pierre Pouillart, Bruce Acres, Nadine Bizouarne, Susy Scholl

Publikováno v: Journal of Biomedicine and Biotechnology, 3, 194-201. Hindawi Publishing Corporation
Journal of Biomedicine and Biotechnology, Vol 2003, Iss 3, Pp 194-201 (2003)
Scholl, S, Squiban, P, Bizouarne, N, Baudin, M, Acres, B, von Mensdorff-Pouilly, S, Shearer, M, Beuzeboc, P, Belle, S, Uzielly, B, Pouillart, P & Taylor-Papdimitriou, J 2003, ' Metastatic breast tumour regression following treatment by a gene-modified vaccinia virus expression MUC1 and IL-2. ', Journal of Biomedicine and Biotechnology, vol. 3, pp. 194-201 . https://doi.org/10.1155/s111072430320704x
Journal of Biomedicine and Biotechnology

MUC1 is expressed by glandular epithelial cells. It is overexpressed in the majority of breast tumours, making it a potential target for immune therapy. The objectives of the present study were to evaluate the anti-tumour activity and tolerance of re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83046b30eb37f89d28ff551cf207c383
https://doi.org/10.1155/s111072430320704x

Studies of clonal cell lines developed from primary breast cancers indicate that the ability to undergo morphogenesis in vitro is lost early in malignancy

Autor: Joyce Taylor-Papadimitriou, Moira Shearer, Jirina Bartkova, Diana Barnes, Rosemary Millis, Feodor Berdichevsky, Jiri Bartek

Publikováno v: International journal of cancer. 51(4)

In an attempt to obtain cell lines from the different components found in primary breast cancers, we used a low-calcium medium to culture epithelial cells of mixed phenotype and a recombinant T antigen containing retrovirus to immortalize cells found

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a83888d474780d890cbeb2218dbbaa6
https://pubmed.ncbi.nlm.nih.gov/1376300

Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus

Autor: Sidney E. Chang, Joyce Taylor-Papadimitriou, El-Nasir Lalani, Zdenka Staskova, Moira Shearer, Jirina Bartkova, Natasha Kyprianou, Jiri Bartek

When defined in terms of markers for normal cell lineages, most invasive breast cancer cells correspond to the phenotype of the common luminal epithelial cell found in the terminal ductal lobular units. Luminal epithelial cells cultured from milk, wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2910bf9699acc2e5cb273f52d0a623f4
https://europepmc.org/articles/PMC51483/

Anchorage-independent growth of normal calf lens epithelial cells and effect of SV40 transformation on their growth properties

Autor: Joyce Taylor-Papadimitriou, Moira Shearer

Publikováno v: Journal of Cellular Physiology. 108:385-391

Calf lens epithelial cells cultured in vitro show growth properties usually associated with virally transformed fibroblasts. The lens cells are anchorage independent, forming colonies in agar, and show a low requirement for added mitogens. In dense c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e3236ac59731198cd4e1df10c53c54
https://doi.org/10.1002/jcp.1041080312

Method for bulk culture of animal cells on plastic film

Autor: W. House, N.G. Maroudas, Moira Shearer

Publikováno v: Experimental Cell Research. 71:293-296

A method is described for the culture of anchorage-dependent cells, on rolls of transparent, autoclavable plastic film. The film is wound into the form of a disposable spiral, which is inserted into a culture vessel. A 2 1 plastic vessel contains a s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7cc7fb08d00e62d7c8d61cfd6adaa8
https://doi.org/10.1016/0014-4827(72)90296-0