Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Moira Sauane"'
Autor:
Erna Mitaishvili, Hanna Feinsod, Zachary David, Jessica Shpigel, Chelsea Fernandez, Moira Sauane, Columba de la Parra
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 99 (2024)
Altered metabolism represents a fundamental difference between cancer cells and normal cells. Cancer cells have a unique ability to reprogram their metabolism by deviating their reliance from primarily oxidative phosphorylation (OXPHOS) to glycolysis
Externí odkaz:
https://doaj.org/article/066b41ab322d42e2b36f720dc8cf2209
Publikováno v:
Cells, Vol 9, Iss 3, p 621 (2020)
Rho GTPases, including Rho, Cdc42, Rac and ROP subfamilies, are key signaling molecules in RNA polymerase II (Pol II) transcriptional control. Our prior work has shown that plant ROP and yeast Cdc42 GTPases similarly modulate Ser2 and Ser5 phosphoryl
Externí odkaz:
https://doaj.org/article/5843804968b44f628dad1b4fe9fdaf9b
Publikováno v:
Non-Coding RNA, Vol 5, Iss 1, p 10 (2019)
Prostate cancer (PCa) is the second leading cause of cancer death in the United States. The five-year survival rate for men diagnosed with localized PCa is nearly 100%, yet for those diagnosed with aggressive PCa, it is less than 30%. The pleiotropic
Externí odkaz:
https://doaj.org/article/58b278a9cfc445cd8fd17b40a8a05efc
Autor:
Leah Persaud, Jason Mighty, Xuelin Zhong, Ashleigh Francis, Marifer Mendez, Hilal Muharam, Stephen M. Redenti, Dibash Das, Bertal Huseyin Aktas, Moira Sauane
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3561 (2018)
Interleukin 24 (IL-24) is a tumor-suppressing protein, which inhibits angiogenesis and induces cancer cell-specific apoptosis. We have shown that IL-24 regulates apoptosis through phosphorylated eukaryotic initiation factor 2 alpha (eIF2α) during en
Externí odkaz:
https://doaj.org/article/7b2b7b4e26304a4bb4546f8a402a7d61
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/26506a091f91488b98507852bdc436fb
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83906 (2013)
A growing number of studies are evaluating retinal progenitor cell (RPC) transplantation as an approach to repair retinal degeneration and restore visual function. To advance cell-replacement strategies for a practical retinal therapy, it is importan
Externí odkaz:
https://doaj.org/article/3b01313d50aa42f89d8cab1d3f38251a
Autor:
Leah Persaud, Dayenny De Jesus, Oliver Brannigan, Maria Richiez-Paredes, Jeannette Huaman, Giselle Alvarado, Linda Riker, Gissete Mendez, Jordan Dejoie, Moira Sauane
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 6, p 869 (2016)
Interleukin 24 (IL-24) is an important pleiotropic immunoregulatory cytokine, whose gene is located in human chromosome 1q32-33. IL-24’s signaling pathways have diverse biological functions related to cell differentiation, proliferation, developmen
Externí odkaz:
https://doaj.org/article/e547a92c87704c13b8d0287c27ce9f3a
Publikováno v:
Cells, Vol 9, Iss 3, p 621 (2020)
Cells
Volume 9
Issue 3
Cells
Volume 9
Issue 3
Rho GTPases, including Rho, Cdc42, Rac and ROP subfamilies, are key signaling molecules in RNA polymerase II (Pol II) transcriptional control. Our prior work has shown that plant ROP and yeast Cdc42 GTPases similarly modulate Ser2 and Ser5 phosphoryl
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 29:A109-A109
Prostate cancer (PCa) incidence and mortality are highest in African American men (AAM) and the molecular mechanisms underlying the racial disparities in PCa are unclear. Interleukin-24 (IL-24), a tumor suppressor whose expression is lost in most hum
Autor:
Devanand Sarkar, Zao-zhong Su, Irina V. Lebedeva, Moira Sauane, Rahul V. Gopalkrishnan, Paul Dent, Paul B. Fisher
Publikováno v:
BioTechniques, Vol 33, Iss 4S, Pp S30-S39 (2002)
One hallmark of neoplasia is abnormal differentiation. Induction of differentiation, by chemical or biological methods, provides a possible therapeutic intervention. “Differentiation therapy” is well documented in several model systems. These inc
Externí odkaz:
https://doaj.org/article/e145a02e01e54f3db3a567bf4afdd39d