Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Moira Hibbs"'
Autor:
Stephen Macdonald, Erika Bosio, Gerben Keijzers, Sally Burrows, Moira Hibbs, Helen O’Donoghue, David Taylor, Ashes Mukherjee, Frances Kinnear, Lisa Smart, Juan-Carlos Ascencio-Lane, Edward Litton, John Fraser, Nathan I. Shapiro, Glenn Arendts, Daniel Fatovich, The REFRESH Trial Investigators
Publikováno v:
Intensive Care Medicine Experimental, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Purpose To investigate the effect of IV fluid resuscitation on endothelial glycocalyx (EG) shedding and activation of the vascular endothelium and inflammation. Materials and methods A planned biomarker sub-study of the REFRESH trial in whic
Externí odkaz:
https://doaj.org/article/0d3db074e6d8466e9db36b16d6e0b514
Autor:
Mijeong Kim, Manjot Singh, Bum-Kyu Lee, Moira Hibbs, Kirsty Richardson, Lesley Ellies, Larissa Wintle, Lisa M. Stuart, Jenny Y. Wang, Dominic C. Voon, Pilar Blancafort, Jianlong Wang, Jonghwan Kim, Peter J. Leedman, Andrew J. Woo
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract The MYC proto-oncogene (MYC) is one of the most frequently overexpressed genes in breast cancer that drives cancer stem cell-like traits, resulting in aggressive disease progression and poor prognosis. In this study, we identified zinc finge
Externí odkaz:
https://doaj.org/article/3a2eb9d8862b4252af620303b3ec1a97
Autor:
Lakshini Yasaswi Herat, Jennifer Rose Matthews, Moira Hibbs, Elizabeth Piroska Rakoczy, Markus Peter Schlaich, Vance Bruce Matthews
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107260- (2023)
Summary: Sodium glucose cotransporters (SGLTs) are transport proteins that are expressed throughout the body. Inhibition of SGLTs is a relatively novel therapeutic strategy to improve glycemic control and has been shown to promote cardiorenal benefit
Externí odkaz:
https://doaj.org/article/34569e1d9c494d1d99cdd00954c950c2
Autor:
Stephen Macdonald, Erika Bosio, Nathan I. Shapiro, Lois Balmer, Sally Burrows, Moira Hibbs, Thomas Jowitt, Lisa Smart, Glenn Arendts, Daniel Fatovich
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Endothelial glycocalyx (EG) shedding is associated with septic shock and described following intravenous (IV) fluid administration. To investigate the possible impact of IV fluids on the pathobiology of septic shock we investigated associati
Externí odkaz:
https://doaj.org/article/fcd7395ba0ee44a6a97369451339a26f
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 819 (2023)
Hyperactivation of the sympathetic nervous system (SNS) has been demonstrated in various conditions including obesity, hypertension and type 2 diabetes. Elevated levels of the major neurotransmitter of the SNS, norepinephrine (NE), is a cardinal feat
Externí odkaz:
https://doaj.org/article/bce628d52ac24c7eba77ff939a8c0259
Autor:
Andrew J. Woo, Chelsea-Ann A. Patry, Alireza Ghamari, Gabriela Pregernig, Daniel Yuan, Kangni Zheng, Taylor Piers, Moira Hibbs, Ji Li, Miguel Fidalgo, Jenny Y. Wang, Joo-Hyeon Lee, Peter J. Leedman, Jianlong Wang, Ernest Fraenkel, Alan B. Cantor
Publikováno v:
Blood Advances, Vol 3, Iss 16, Pp 2499-2511 (2019)
Abstract: Erythroid maturation requires the concerted action of a core set of transcription factors. We previously identified the Krüppel-type zinc finger transcription factor Zfp148 (also called ZBP-89) as an interacting partner of the master eryth
Externí odkaz:
https://doaj.org/article/a4a01af35491446d8737b36cfb40774b
Autor:
Stephen Macdonald, Erika Bosio, Gerben Keijzers, Sally Burrows, Moira Hibbs, Helen O’Donoghue, David Taylor, Ashes Mukherjee, Frances Kinnear, Lisa Smart, Juan-Carlos Ascencio-Lane, Edward Litton, John Fraser, Nathan I. Shapiro, Glenn Arendts, Daniel Fatovich
INTRODUCTIONIntravenous (IV) fluid resuscitation is recommended first line therapy in septic shock, but the effectiveness and safety of this approach has been questioned. To investigate potential mechanisms of harm from IV fluid resuscitation, we mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd42f559107fe5121b3bcba2cf11fec
https://doi.org/10.21203/rs.3.rs-1714832/v1
https://doi.org/10.21203/rs.3.rs-1714832/v1
Autor:
Lakshini Herat, Jennifer Matthews, Moira Hibbs, Elizabeth Rakoczy, Markus P. Schlaich, Vance Matthews
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48d774fe8d2a87e004b46d15c8a3f7c
https://doi.org/10.2139/ssrn.4234697
https://doi.org/10.2139/ssrn.4234697