Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Moira A. Elmore"'
Autor:
Richard Goodwin, Fiona Thomson, John W. Clark, Brad Sherborne, Lynn Watson, Angus R. Brown, Morag Grassie, Jack Pick, Angela Cowley, Olaf Nimz, J. Richard Morphy, Lorraine McIntosh, Niall M. Hamilton, Littlewood Peter Thomas Albert, Alasdair Smith, Koc-Kan Ho, Michael Speake, Alison Hillier, Ashvin Mistry, Michael Bosies, Simon James Anthony Grove, Mark Craighead, Theresa McIntyre, Michael Kiczun, Grant Emma Jane, Moira A. Elmore, Hannah Hampson, Mark Weston, Susan MacDonald, Susan Goutcher, Scott J. Lusher, Gayle Spinks, Zoran Rankovic, Michael Ohlmeyer, Helen Cameron, Alistair Firth, Steven G. Kultgen, Celia Kingsbury
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:137-140
High-throughput screening of 3.87 million compounds delivered a novel series of non-steroidal GR antagonists. Subsequent rounds of optimisation allowed progression from a non-selective ligand with a poor ADMET profile to an orally bioavailable, selec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62da153327bd28fcc24657573e661d2
https://doi.org/10.1016/j.bmcl.2010.11.054
https://doi.org/10.1016/j.bmcl.2010.11.054
Autor:
Moira A. Elmore, Maxine E. Hill, Ashraff A. Makda, Kenneth Kelly, Alasdair C. Stamps, Michael J. Finnen
Publikováno v:
Biochemical Journal. 326:455-461
A novel human homologue of Escherichia coli, yeast and plant 1-acylglycerol-3-phosphate acyltransferase has been isolated from U937 cell cDNA. Expression of the cloned sequence in 1-acylglycerol-3-phosphate acyltransferase-deficient E. coli resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c36db539a54523da86e81d25c7d8ebf
https://doi.org/10.1042/bj3260455
https://doi.org/10.1042/bj3260455
Autor:
Maxine E. Hill, Michael J. Finnen, Moira A. Elmore, John M. Lackie, Shimizu Yasuaki, R.Hugh Daniels
Publikováno v:
Biochemical Pharmacology. 45:1743-1751
When human peripheral blood neutrophils were stimulated with various agonists which activate and/or prime neutrophils, we found that Cl − efflux was enhanced with a dramatic (50%) loss of intracellular Cl − . Interestingly, the Cl − efflux was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92ec6fd8481a99fe1620c819df8398bd
https://doi.org/10.1016/0006-2952(93)90429-z
https://doi.org/10.1016/0006-2952(93)90429-z
Publikováno v:
FEBS Letters. 269:283-287
In vitro phosphorylation of platelet subcellular fractions revealed that most of the alkali-resistant phosphoproteins and the majority of pp60c-src were in the surface membrane fraction. An alkali-resistant phosphoprotein of about 100 kDa was also im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051ce7250ff82f66919783d6b1c48f07
https://doi.org/10.1016/0014-5793(90)81177-p
https://doi.org/10.1016/0014-5793(90)81177-p
Publikováno v:
Neuropeptides. 15:31-36
In this study the substrate specificity of a pyroglutamate aminopeptidase from synaptosomal membranes of guinea-pig brain was investigated. The enzyme was found to be specific for tripeptides, tripeptide-amides and tetrapeptides which possess the N-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa207e635d9be45585cabe5123c61743
https://doi.org/10.1016/0143-4179(90)90157-t
https://doi.org/10.1016/0143-4179(90)90157-t
Publikováno v:
Biochemical Society transactions. 25(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d32f97c4be1d891410e93a07a6759b
https://pubmed.ncbi.nlm.nih.gov/9191394
https://pubmed.ncbi.nlm.nih.gov/9191394
Publikováno v:
Journal of neurochemistry. 54(1)
In this article, the enzymes of brain and associated tissues that can degrade thyrotropin-releasing hormone (TRH) and luteinising hormone-releasing hormone (LH-RH) are reviewed. As both TRH and LH-RH are considered to act as neurotransmitters or neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae93f05873483045cd7cc915dbc62ad5
https://pubmed.ncbi.nlm.nih.gov/2104543
https://pubmed.ncbi.nlm.nih.gov/2104543
Autor:
Edward A. McKenzie, Edward J. R. Maughfling, Moira A. Elmore, Alasdair Craig Stamps, Ashraff A. Makda, Maxine E. Hill, Michael J. Finnen
Publikováno v:
Biochemical Society Transactions. 27:A125-A125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e71afdfc4ac960f25f279903e5db9a
https://doi.org/10.1042/bst027a125a
https://doi.org/10.1042/bst027a125a
Autor:
Maxine E. Hill, Smita Tejura, Alasdair C. Stamps, Moira A. Elmore, Ashraff A. Makda, Michael J. Finnen
Publikováno v:
Biochemical Society Transactions. 25:217S-217S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423377678664e5a90ee0d1851ad981b2
https://doi.org/10.1042/bst025217s
https://doi.org/10.1042/bst025217s
Publikováno v:
Biochemical Society Transactions. 22:136S-136S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6382a01fb6c9b2fec103c00559312a2b
https://doi.org/10.1042/bst022136s
https://doi.org/10.1042/bst022136s