Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Moin U. Fareed"'
Autor:
Vitaliy Poylin, Moin U. Fareed, Patrick O'Neal, Nima Alamdari, Natasha Reilly, Michael Menconi, Per-Olof Hasselgren
Publikováno v:
Mediators of Inflammation, Vol 2008 (2008)
We tested the hypothesis that treatment of rats with curcumin prevents sepsis-induced muscle protein degradation. In addition, we determined the influence of curcumin on different proteolytic pathways that are activated in septic muscle (i.e., ubiqui
Externí odkaz:
https://doaj.org/article/1f2550a14cc548a68e73756521e0a5bd
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 37:2226-2238
Sepsis is associated with muscle wasting, mainly reflecting increased muscle proteolysis. Recent studies suggest that inhibition of GSK-3beta activity may counteract catabolic stimuli in skeletal muscle. We tested the hypothesis that treatment of mus
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 37:2156-2168
Muscle wasting in sepsis is associated with increased expression of messenger RNA for several genes in the ubiquitin-proteasome proteolytic pathway, indicating that increased gene transcription is involved in the development of muscle atrophy. Here w
Autor:
Moin U. Fareed, Michael J. Menconi, Hongmei Yang, Wei Wei, Amy Evenson, Per-Olof Hasselgren, Victoria Petkova
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 288:R580-R590
We examined the influence of sepsis on the expression and activity of the calpain and caspase systems in skeletal muscle. Sepsis was induced in rats by cecal ligation and puncture (CLP). Control rats were sham operated. Calpain activity was determine
Autor:
Michael J. Menconi, Vitaliy Poylin, Patrick O'Neal, Moin U. Fareed, Per-Olof Hasselgren, Nima Alamdari, Natasha Reilly
Publikováno v:
Mediators of Inflammation, Vol 2008 (2008)
Mediators of Inflammation
Mediators of Inflammation
We tested the hypothesis that treatment of rats with curcumin prevents sepsis-induced muscle protein degradation. In addition, we determined the influence of curcumin on different proteolytic pathways that are activated in septic muscle (i.e., ubiqui
Autor:
Patrick O'Neal, Per-Olof Hasselgren, Moin U. Fareed, Michael J. Menconi, Vitaliy Poylin, Wei Wei
Publikováno v:
Critical care medicine. 35
Objective: To review glucocorticoid-regulated molecular mechanisms of muscle wasting. Design: Review of recent literature describing the role of glucocorticoids in the regulation of proteolytic mechanisms, transcription factors, and nuclear cofactors
Autor:
Moin U. Fareed, Amy Evenson, Per-Olof Hasselgren, Wei Wei, Vitaliy Poylin, Michael J. Menconi, Bernadette Pignol, Victoria Petkova
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 290(6)
Muscle wasting in sepsis is a significant clinical problem because it results in muscle weakness and fatigue that may delay ambulation and increase the risk for thromboembolic and pulmonary complications. Treatments aimed at preventing or reducing mu
Autor:
Wei Wei, Michael J. Menconi, Joshua M.V. Mammen, Per-Olof Hasselgren, Victoria Petkova, Amy Evenson, Moin U. Fareed, Hongmei Yang
Publikováno v:
Journal of cellular physiology. 204(1)
The influence of glucocorticoids on the expression and activity of the transcription factors CCAAT/enhancer binding protein (C/EBP)beta and delta in skeletal muscle was examined by treating rats or cultured L6 myotubes with dexamethasone. Treatment o
We showed previously that subcutaneous injection of the injury-associated peptide mediator endothelin-1 (ET-1) into the rat plantar hindpaw produces pain behavior and selective excitation of nociceptors, both through activation of ET(A) receptors lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75931262ef7268ce2534addfbaf9edb9
https://europepmc.org/articles/PMC6757974/
https://europepmc.org/articles/PMC6757974/
Publikováno v:
Neuroreport. 9(10)
We examined whether endothelin-1 (ET-1), a potent vasoconstrictive peptide secreted in high concentration by metastatic prostate cancer cells, produces endothelin receptor-dependent pain behavior when applied to rat sciatic nerve. ET-1 (200-800 micro