Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Moiani A"'
Autor:
Arianna Moiani, Gil Letort, Sabrina Lizot, Anne Chalumeau, Chloe Foray, Tristan Felix, Diane Le Clerre, Sonal Temburni-Blake, Patrick Hong, Sophie Leduc, Noemie Pinard, Alan Marechal, Eduardo Seclen, Alex Boyne, Louisa Mayer, Robert Hong, Sylvain Pulicani, Roman Galetto, Agnès Gouble, Marina Cavazzana, Alexandre Juillerat, Annarita Miccio, Aymeric Duclert, Philippe Duchateau, Julien Valton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Sickle cell disease is a devastating blood disorder that originates from a single point mutation in the HBB gene coding for hemoglobin. Here, we develop a GMP-compatible TALEN-mediated gene editing process enabling efficient HBB correction v
Externí odkaz:
https://doaj.org/article/a5ed07ba92514c729d823ca1c6aa5120
Autor:
Poggi, Lucie, Chentout, Loïc, Lizot, Sabrina, Boyne, Alex, Juillerat, Alexandre, Moiani, Arianna, Luka, Marine, Carbone, Francesco, Ménager, Mickael, Cavazzana, Marina, Duchateau, Philippe, Valton, Julien, Kracker, Sven
Publikováno v:
In Molecular Therapy - Methods & Clinical Development 14 December 2023 31
Akademický článek
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Akademický článek
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Autor:
Jerry H. Houl, Zu Ye, Chris A. Brosey, Lakshitha P. F. Balapiti-Modarage, Sarita Namjoshi, Albino Bacolla, Daniel Laverty, Brian L. Walker, Yasin Pourfarjam, Leslie S. Warden, Naga Babu Chinnam, Davide Moiani, Roderick A. Stegeman, Mei-Kuang Chen, Mien-Chie Hung, Zachary D. Nagel, Tom Ellenberger, In-Kwon Kim, Darin E. Jones, Zamal Ahmed, John A. Tainer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
PARG catalyzes the removal of poly(ADP-ribose) (PAR) from target proteins and executes critical functions in the DNA damage response. Here the authors provide structural and biological insight with small molecule PARG inhibitors and show that PARG in
Externí odkaz:
https://doaj.org/article/b8239efdcde244de83ae43188c91b2d3
Autor:
Annalisa Lattanzi, Stephanie Duguez, Arianna Moiani, Araksya Izmiryan, Elena Barbon, Samia Martin, Kamel Mamchaoui, Vincent Mouly, Francesco Bernardi, Fulvio Mavilio, Matteo Bovolenta
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 11-19 (2017)
Exonic duplications account for 10%–15% of all mutations in Duchenne muscular dystrophy (DMD), a severe hereditary neuromuscular disorder. We report a CRISPR (clustered regularly interspaced short palindromic repeat)/Cas9-based strategy to correct
Externí odkaz:
https://doaj.org/article/88c9ce137af0434d9ad8ef36a9936d97
Autor:
Dihua Yu, John A. Tainer, Jenny C. Chang, Shao-Cong Sun, Haoqiang Ying, Wen-Ling Kuo, Xianghua Liu, Yohei Saito, Akosua Badu-Nkansah, Chenyu Zhang, Ping Li, Arseniy E. Yuzhalin, Lin Zhang, Hongzhong Li, Jun Yao, Davide Moiani, Zamal Ahmed, Yuan Zhang, Yutao Qi, Kai Sun, Yi Xiao, Yimin Duan, Xiangliang Yuan
Supplementary Data from Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154bc5981696651ae8cde6a89bc4e522
https://doi.org/10.1158/2159-8290.22541254
https://doi.org/10.1158/2159-8290.22541254
Autor:
Dihua Yu, John A. Tainer, Jenny C. Chang, Shao-Cong Sun, Haoqiang Ying, Wen-Ling Kuo, Xianghua Liu, Yohei Saito, Akosua Badu-Nkansah, Chenyu Zhang, Ping Li, Arseniy E. Yuzhalin, Lin Zhang, Hongzhong Li, Jun Yao, Davide Moiani, Zamal Ahmed, Yuan Zhang, Yutao Qi, Kai Sun, Yi Xiao, Yimin Duan, Xiangliang Yuan
Despite the popular use of dietary supplements during conventional cancer treatments, their impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint therapy (ICT), are unknown. Surprisingly, our analyses of electronic healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbadfae3bf1ca3b84fe40c1ef2c54ec8
https://doi.org/10.1158/2159-8290.c.6549589.v1
https://doi.org/10.1158/2159-8290.c.6549589.v1
Autor:
Xiangliang Yuan, Yimin Duan, Yi Xiao, Kai Sun, Yutao Qi, Yuan Zhang, Zamal Ahmed, Davide Moiani, Jun Yao, Hongzhong Li, Lin Zhang, Arseniy E. Yuzhalin, Ping Li, Chenyu Zhang, Akosua Badu-Nkansah, Yohei Saito, Xianghua Liu, Wen-Ling Kuo, Haoqiang Ying, Shao-Cong Sun, Jenny C. Chang, John A. Tainer, Dihua Yu
Publikováno v:
Cancer Discov
Despite the popular use of dietary supplements during conventional cancer treatments, their impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint therapy (ICT), are unknown. Surprisingly, our analyses of electronic healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5985879b0d56272b3b7831d3f94d5c50
https://doi.org/10.1158/2159-8290.cd-21-0900
https://doi.org/10.1158/2159-8290.cd-21-0900
Autor:
Chris A. Brosey, Runze Shen, Davide Moiani, Darin E. Jones, Kathryn Burnett, Greg L. Hura, John A. Tainer
Publikováno v:
Small Angle Scattering Part B: Methods for Structural Interpretation ISBN: 9780323991810
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9751060d4c2ee5d3eaaa6f6b8e32282b
https://doi.org/10.1016/bs.mie.2022.09.022
https://doi.org/10.1016/bs.mie.2022.09.022