Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mohtashim H, Shamsi"'
Autor:
Omair Adil, Mohtashim H. Shamsi
Publikováno v:
Biosensors, Vol 13, Iss 2, p 247 (2023)
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder, which has complex diagnostic steps. Electrochemical immunoassays may make the diagnosis simpler and faster. Here, we present the detection of ALS-associated neurofilament light chai
Externí odkaz:
https://doaj.org/article/e6f4eac5c26d4e0ba0b0cfc82b23b744
Autor:
Narges Asefifeyzabadi, Torrey E. Holland, Poopalasingam Sivakumar, Saikat Talapatra, Ishani M. Senanayake, Boyd M. Goodson, Mohtashim H. Shamsi
Publikováno v:
Biosensors, Vol 11, Iss 8, p 273 (2021)
DNA is strongly adsorbed on oxidized graphene surfaces in the presence of divalent cations. Here, we studied the effect of DNA adsorption on electrochemical charge transfer at few-layered, oxygen-functionalized graphene (GOx) electrodes. DNA adsorpti
Externí odkaz:
https://doaj.org/article/1112f0cd5a014091b54173760db8ce8c
Autor:
Narges Asefifeyzabadi, Grace Durocher, Kizito-Tshitoko Tshilenge, Tanimul Alam, Lisa M. Ellerby, Mohtashim H. Shamsi
Publikováno v:
RSC Advances. 12:7757-7761
We present a PNA microprobe sensing platform to detect trinucleotide repeat mutation by electrochemical impedance spectroscopy. The microprobe platform discriminated Huntington's disease-associated CAG repeats in cell-derived total RNA with S/N 1 : 3
Autor:
Mohtashim H. Shamsi, Meera Patwardhan, Ahmad Zaman Qamar, Rana Alkhaldi, Saikat Talapatra, Keith T. Gagnon, Adrian A Pater, Narges Asefifeyzabadi
Publikováno v:
ACS Applied Materials & Interfaces. 12:52156-52165
Flexible and ultrasensitive biosensing platforms capable of detecting a large number of trinucleotide repeats (TNRs) are crucial for future technology development needed to combat a variety of genetic disorders. For example, trinucleotide CGG repeat
Autor:
Ishani M Senanayake, Boyd M. Goodson, Mohtashim H. Shamsi, Saikat Talapatra, Poopalasingam Sivakumar, Narges Asefifeyzabadi, Torrey Holland
Publikováno v:
Biosensors, Vol 11, Iss 273, p 273 (2021)
Biosensors
Volume 11
Issue 8
Biosensors
Volume 11
Issue 8
DNA is strongly adsorbed on oxidized graphene surfaces in the presence of divalent cations. Here, we studied the effect of DNA adsorption on electrochemical charge transfer at few-layered, oxygen-functionalized graphene (GOx) electrodes. DNA adsorpti
Autor:
Grace Durocher, Narges Asefifeyzabadi, Lisa M. Ellerby, Mohtashim H. Shamsi, Kizito-Tshitoko Tshilenge
We present a PNA-based microprobe sensing platform to detect nucleic acid repeat mutations by electrochemical impedance spectroscopy. The microprobe platform discriminated Huntington’s disease-associated CAG repeats in cell-derived total RNA. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e04c3a10e2c45f06d4df558a763e5f
https://doi.org/10.26434/chemrxiv-2021-p9f5h
https://doi.org/10.26434/chemrxiv-2021-p9f5h
Autor:
Narges Asefifeyzabadi, Prabhangshu Kumer Das, Mohtashim H. Shamsi, Avokerie Hillary Onorimuo, Grace Durocher
Publikováno v:
RSC advances. 11(45)
DNA interfaces with nano, micro, and macro materials have gained widespread attention for various applications. Such interfaces exhibit distinct functions and properties not only due to the unique properties of interfacing materials but also sequence
Autor:
Swati Naphade, Keith T. Gagnon, Motahareh Taki, Lisa M. Ellerby, Kushal J. Rohilla, Madison Funneman, Najiyah Benzabeh, Mohtashim H. Shamsi, Maria Barton
Publikováno v:
Anal Bioanal Chem
DNA repeat expansion sequences cause a myriad of neurological diseases when they expand beyond a critical threshold. Previous electrochemical approaches focused on the detection of trinucleotide repeats (CAG, CGG, and GAA) and relied on labeling of t
Autor:
Narges, Asefifeyzabadi, Rana, Alkhaldi, Ahmad Z, Qamar, Adrian A, Pater, Meera, Patwardhan, Keith T, Gagnon, Saikat, Talapatra, Mohtashim H, Shamsi
Publikováno v:
ACS applied materialsinterfaces. 12(46)
Flexible and ultrasensitive biosensing platforms capable of detecting a large number of trinucleotide repeats (TNRs) are crucial for future technology development needed to combat a variety of genetic disorders. For example, trinucleotide CGG repeat
Publikováno v:
Journal of materials chemistry. B. 8(24)
Trinucleotide repeat (TNR) sequences widely exist in nature and their overgrowth is associated with two dozen neurodegenerative diseases in humans. These sequences have a unique helical flexibility, which affects their biophysical properties. A numbe