Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mohtadin Hashemi"'
Autor:
Sridhar Vemulapalli, Mohtadin Hashemi, Yingling Chen, Suravi Pramanik, Kishor K. Bhakat, Yuri L. Lyubchenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5145 (2024)
Apurinic/apyrimidinic endonuclease 1 (APE1) is involved in DNA repair and transcriptional regulation mechanisms. This multifunctional activity of APE1 should be supported by specific structural properties of APE1 that have not yet been elucidated. He
Externí odkaz:
https://doaj.org/article/a025fa60abe14ade8e93dc4103207008
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9800 (2023)
The synaptic protein–DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites an
Externí odkaz:
https://doaj.org/article/62a0bc7f84b143ce897c63e1a3e3e20e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12916 (2022)
The interplay between the mechanical properties of double-stranded and single-stranded DNA is a phenomenon that contributes to various genetic processes in which both types of DNA structures coexist. Highly stiff DNA duplexes can stretch single-stran
Externí odkaz:
https://doaj.org/article/155c7c912eb64f658614625870056fd9
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2803 (2022)
The effects of membranes on the early-stage aggregation of amyloid β (Aβ) have come to light as potential mechanisms by which neurotoxic species are formed in Alzheimer’s disease. We have shown that direct Aβ-membrane interactions dramatically e
Externí odkaz:
https://doaj.org/article/c189bac471c449abbaba402130830fd4
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 212 (2021)
The assembly of synaptic protein-DNA complexes by specialized proteins is critical for bringing together two distant sites within a DNA molecule or bridging two DNA molecules. The assembly of such synaptosomes is needed in numerous genetic processes
Externí odkaz:
https://doaj.org/article/4e073f5e0c794145ad1bcfef621b96c6
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Structural investigations have revealed that β hairpin structures are common features in amyloid fibrils, suggesting that these motifs play an important role in amyloid assembly. To test this hypothesis, we characterized the effect of the h
Externí odkaz:
https://doaj.org/article/27bd31e827a34c1190ad6b96672f031f
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1129 (2020)
The self-assembly of amyloid β (Aβ) proteins into oligomers is the major pathogenic event leading to Alzheimer’s disease (AD). Typical in vitro experiments require high protein concentrations, whereas the physiological concentration of Aβ is in
Externí odkaz:
https://doaj.org/article/70e793bbefd5490c9f84c19c5acb2265
Publikováno v:
The Journal of Physical Chemistry B. 126:10813-10821
The organization of the nucleosome array is a critical component of the chromatin assembly into higher order structure as well as its function. Here, we investigated the contributions of the DNA sequence and internucleosomal interactions on the organ
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9800
The synaptic protein–DNA complexes, formed by specialized proteins that bridge two or more distant sites on DNA, are critically involved in various genetic processes. However, the molecular mechanism by which the protein searches for these sites an
The organization of the nucleosome array is a critical component of the chromatin assembly into higher order structure as well as its function. Here we investigated the contribution of the DNA sequence and internucleosomal interactions to the organiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::523dbde1df13f1b7c8ed8431e6467b97
https://doi.org/10.1101/2022.07.20.500866
https://doi.org/10.1101/2022.07.20.500866