Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Mohsen Nemat-Gorgani"'
Autor:
Ebrahim Rostampour Ghareghozloo, Mohsen Mahdavimehr, Ali Akbar Meratan, Nasser Nikfarjam, Atiyeh Ghasemi, Bentolhoda Katebi, Mohsen Nemat-Gorgani
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244296 (2020)
There are many reports demonstrating that various derivatives of carbon nanoparticles are effective inhibitors of protein aggregation. As surface structural features of nanoparticles play a key role on modulating amyloid fibrillation process, in the
Externí odkaz:
https://doaj.org/article/7c812c0db006448bae87267c54bfce68
Autor:
Mohsen Mahdavimehr, Ali Akbar Meratan, Maryam Ghobeh, Atiyeh Ghasemi, Ali Akbar Saboury, Mohsen Nemat-Gorgani
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187841 (2017)
Among therapeutic approaches for amyloid-related diseases, attention has recently turned to the use of natural products as effective anti-aggregation compounds. Although a wealth of in vitro and in vivo evidence indicates some common inhibitory activ
Externí odkaz:
https://doaj.org/article/dd17bb0d7686458db2674b2b8d85ff56
Autor:
Hassan Ramshini, Claudia Parrini, Annalisa Relini, Mariagioia Zampagni, Benedetta Mannini, Alessandra Pesce, Ali Akbar Saboury, Mohsen Nemat-Gorgani, Fabrizio Chiti
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16075 (2011)
The assembly of soluble proteins into ordered fibrillar aggregates with cross-β structure is an essential event of many human diseases. The polypeptides undergoing aggregation are generally small in size. To explore if the small size is a primary de
Externí odkaz:
https://doaj.org/article/33fcc30ff15249b6b0763167e603e10a
Autor:
Ramin Zadali, Ali Akbar Meratan, Mohsen Nemat-Gorgani, Vahid Hassani, Yasin Rafiei, Fatemeh Mamashli
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1864(1)
Alpha-synuclein (α-syn) aggregation and mitochondrial dysfunction are considered as two of the main factors associated with Parkinson's disease (PD). In the present investigation, the effectiveness of the amyloid fibrils obtained from α-syn with th
Autor:
Justin K. Do, Vy Nguyen, Julie Wilhelmy, Ronald W. Davis, Abed Abugherir, Mohsen Nemat-Gorgani, Brendan R. Schmidt, Anand K. Ramasubramanian, Amit K. Saha
Publikováno v:
Clinical Hemorheology and Microcirculation
Background Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a poorly understood disease. Amongst others symptoms, the disease is associated with profound fatigue, cognitive dysfunction, sleep abnormalities, and other symptoms that are m
Autor:
Bentolhoda Katebi, Mohsen Nemat-Gorgani, Atiyeh Ghasemi, Ebrahim Rostampour Ghareghozloo, Nasser Nikfarjam, Mohsen Mahdavimehr, Ali Akbar Meratan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244296 (2020)
PLoS ONE, Vol 15, Iss 12, p e0244296 (2020)
There are many reports demonstrating that various derivatives of carbon nanoparticles are effective inhibitors of protein aggregation. As surface structural features of nanoparticles play a key role on modulating amyloid fibrillation process, in the
Publikováno v:
International Journal of Biological Macromolecules. 92:573-580
Peptides and proteins convert from their native states to amyloid fibrillar aggregates in a number of pathological conditions. Characterizing these species could provide useful information on their pathogenicity and the key factors involved in their
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 116, iss 21
There is not currently a well-established, if any, biological test to diagnose myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The molecular aberrations observed in numerous studies of ME/CFS blood cells offer the opportunity to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32747f737a624e7853b8824349ffac8
https://escholarship.org/uc/item/3h51c7vp
https://escholarship.org/uc/item/3h51c7vp
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1862:183251
Extensive research has shown that assembling of α-synuclein amyloid aggregates on mitochondria is an important mechanistic feature of Parkinson's disease (PD) and other Lewy body disorders. However, the molecular mechanism(s) of its neuronal toxicit
Autor:
Ali Akbar Meratan, Bentolhoda Katebi, Mohsen Nemat-Gorgani, Atiyeh Ghasemi, Mohsen Mahdavimehr
Publikováno v:
Archives of biochemistry and biophysics. 659
A growing body of evidence suggests that secretion and assembly of insulin to amyloid fibrils reduce its efficacy in treating type II diabetes and may lead to dysfunctioning of several organs. The research presented here explores the effects of silib