Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Mohsen A. Hedaya"'
Autor:
Ehab S. El Desoky, Sherif I. Kamel, Ahlam M. Farghaly, Madiha Y. Bakheet, Mohsen A. Hedaya, Jean-Pascal Siest
Publikováno v:
Biomarker Insights, Vol 1, Pp 157-164 (2006)
Summary: The urinary ratio of 6 ß-hydroxycortisol/cortisol (6 ß-OHC/C) as a biomarker of CYP3A4 metabolizing activity has been studied in Egyptian patients with chronic liver cirrhosis associated with previous hepatic Schistosomiasis infection to d
Externí odkaz:
https://doaj.org/article/c4187fcf1cf7457cb1d10f3564ba8045
Autor:
Mohsen A. Hedaya, Vidhya Thomas, Mohamed E. Abdel-Hamid, Elijah O. Kehinde, Oludotun A. Phillips
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 34 (2017)
This is a comparative pharmacokinetics study of linezolid (Lzd), and two novel oxazolidinone antibacterial agents—PH027 and PH051—in rabbits to determine if the discrepancy between the in vitro and in vivo activities of the novel compounds is due
Externí odkaz:
https://doaj.org/article/b1c60f8a02134c15a281527c97f101b0
Autor:
Ehab S. ELDesoky, Sherif I. Kamel, Ahlam M. Farghaly, Madiha Y. Bakheet, Mohsen A. Hedaya, Jean-Pascal Siest
Publikováno v:
Biomarker Insights, Vol 1 (2006)
Summary The urinary ratio of 6 β-hydroxycortisol/cortisol (6 β-OHC/C) as a biomarker of CYP3A4 metabolizing activity has been studied in Egyptian patients with chronic liver cirrhosis associated with previous hepatic Schistosomiasis infection to de
Externí odkaz:
https://doaj.org/article/974b8e026eb84296a2fe49915e68fb76
Publikováno v:
Journal of Pharmaceutical Sciences. 109:3386-3393
A self-microemulsifying drug delivery system (SMEDDS) was developed to enhance Paclitaxel (PTX) solubility and membrane permeability, thus improve its bioavailability. Pre-formulation studies were performed to optimize PTX-SMEDDS formulation. Then, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa46be8828a80d430dce246ea7129a3
https://doi.org/10.1016/j.xphs.2020.07.027
https://doi.org/10.1016/j.xphs.2020.07.027
Autor:
Mohsen A. Hedaya
This book introduces basic pharmacokinetic concepts to beginner learners to help them understand the absorption, distribution, metabolism, and excretion of drugs. After a basic introduction to pharmacokinetics and its related fields, the book provide
Publikováno v:
Med Princ Pract
Introduction: The objectives were to prepare, characterize, and evaluate different ibuprofen (IBU) nanosuspensions. Methods: The nanosuspensions produced by ultrahomogenization were compared with a marketed IBU suspension for particle size, in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6815a63bd02fff4315698e910e042077
https://pubmed.ncbi.nlm.nih.gov/33823524
https://pubmed.ncbi.nlm.nih.gov/33823524
Publikováno v:
Journal of Drug Delivery Science and Technology. 66:102864
Background In vivo-in vitro correlation (IVIVC) are used during product development for optimization of drug formulations and can serve as a surrogate for bioequivalence studies. Aim This research was performed to investigate the in vitro dissolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc9ee15a40ba28365a5336432fd3b8f
https://doi.org/10.1016/j.jddst.2021.102864
https://doi.org/10.1016/j.jddst.2021.102864
Autor:
Sally A. Helmy, Mohsen A. Hedaya
Publikováno v:
Biopharmaceutics & Drug Disposition. 36:216-231
Purpose To investigate the pharmacokinetic/pharmacodynamic (PK/PD) interaction between irbesartan (IRB) and hydrochlorothiazide (HCT) in normotensive subjects. Methods A three-way crossover study was used. Serial drug concentrations and drug effects,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b1221261c0ce6ff454e228cb3d1e73
https://doi.org/10.1002/bdd.1935
https://doi.org/10.1002/bdd.1935
Autor:
Mohsen A. Hedaya, Elijah O. Kehinde, Mohamed E. Abdel-Hamid, Vidhya Thomas, Oludotun A. Phillips
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1040
Objectives Linezolid is the first approved oxazolidinone antibacterial agent, whereas PH027 is a novel compound of the same class that exhibits good in vitro antibacterial activity. The objective of this study was to develop an UPLC–MS/MS assay for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc1e4dc776d08ec7210b0ae04cf6011
https://pubmed.ncbi.nlm.nih.gov/27978473
https://pubmed.ncbi.nlm.nih.gov/27978473
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 36:45-52
Summary What is known and objective: Neonatal sepsis is one of the most common reasons for admission to neonatal units in developing countries. Aminoglycosides widely used in its treatment are usually administered two or three times a day. Less frequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17da7680398eec66a4f8fe5d49c5087
https://doi.org/10.1111/j.1365-2710.2009.01152.x
https://doi.org/10.1111/j.1365-2710.2009.01152.x