Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Mohsen, Tehrani"'
Autor:
Armin Akbar, Hossein asgariyan-Omran, Reza Valadan, Mohammad-Mehdi Dindarloo, Ahmad Najafi, Amir Kahrizi, Arash Poursheikhani, Hossein Karami, Mohammad Naderi, Shayan Sabeti, Mohsen Tehrani
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 12, Pp 1468-1474 (2023)
Objective(s): Exhausted CD8+ T-cells over-express immune checkpoint receptors (ICRs), which interact with their ligands on malignant cells. However, some ICRs have been reported to be expressed on both T-cells and tumor cells, including V-domain immu
Externí odkaz:
https://doaj.org/article/74445679839c4d0b93ec1a7434d52a26
Autor:
Maryam Mohammadi, Hossein Asgarian-Omran, Behnam Najafi, Ahmad Najafi, Reza Valadan, Hossein Karami, Mohammad Naderisoraki, Maryam Alizadeforutan, Ramin Shekarriz, Mohsen Tehrani
Publikováno v:
Iranian Journal of Immunology, Vol 20, Iss 4, Pp 438-445 (2023)
Background: Thymocyte selection-associated high mobility group box protein (TOX) and members of the nuclear receptor 4A (NR4A) are known as transcription factors involved in T cell exhaustion.Objective: To evaluate the mRNA expression of TOX and NR4A
Externí odkaz:
https://doaj.org/article/9e1db0fc3a11477aa3f681d560a42aa6
Autor:
Seyed Mohammad Javadzadeh, Mohsen Keykhosravi, Mohsen Tehrani, Hossein Asgarian-Omran, Mohsen Rashidi, Hadi Hossein-Nattaj, Laleh Vahedi-Larijani, Abolghasem Ajami
Publikováno v:
Iranian Journal of Immunology, Vol 19, Iss 4, Pp 339-348 (2022)
Background: Innate Lymphoid Cells (ILCs) promote tissue homeostasis, contribute to the immune defense mechanisms, and play important roles in the initiation of immune responses and chronic inflammation. Objective: To understand the roles of innate ly
Externí odkaz:
https://doaj.org/article/dadd7a5a85e842c394adae09fc4b0316
Autor:
Seyed Mohammad Javadzadeh, Mohsen Tehrani, Mohsen Keykhosravi, Rajehe Mohamadian-Amiri, Omolbanin Amjadi, Nasim Hafezi, Ehsan Zabouli, Mobina Montazeriun, Abolghasem Ajami
Publikováno v:
Caspian Journal of Internal Medicine, Vol 13, Iss 4, Pp 693-698 (2022)
Background: Immune checkpoint molecules have critical roles in directing immune responses into co-inhibitory and co-stimulatory signals. Herpes virus entry mediator (HVEM) is a receptor of tumor necrosis factor receptor superfamily with unique featur
Externí odkaz:
https://doaj.org/article/d6d296bfbec64c6c95831eb80cd10d38
Autor:
Zahra Hosseini-khah, Mohammad Reza Babaei, Mohsen Tehrani, Magali Cucchiarini, Henning Madry, Abolghasem Ajami, Nasser Rakhshani, Alireza Rafiei, Behrooz Nikbin
Publikováno v:
Current Oncology, Vol 28, Iss 4, Pp 3015-3029 (2021)
Sex-determining region Y-box 2 (SOX2) is a stem cell transcription factor and a major regulator of self-renewal and pluripotency of cancer stem cells (CSCs). In many types of cancer, SOX2 is dysregulated due to overexpression associated with tumor pr
Externí odkaz:
https://doaj.org/article/2894193eced541e9ba0244198f550d3f
Autor:
Siavash Moradi, Arash Akhlaghi, Roghayeh Valipour Khajegheyasi, Forouzan Sadeghimahalli, Seyedeh Masoumeh Pashaei, Mohsen Tehrani, Seyed Mohammad Mehdi Ghaffari Hamedani, Touraj Assadi, Maryam Sefidgarnia, Fattane Amuei
Publikováno v:
Journal of Medical Education Development, Vol 13, Iss 41, Pp 33-41 (2021)
Externí odkaz:
https://doaj.org/article/f7c5b632d4134d8fb8375e3aaf89330b
Autor:
Saeid Taghiloo, Abolghasem Ajami, Mohsen Tehrani, Arezou Abbasi, Reza Alizadeh-Navaei, Mohsen Akhiani, Alireza Salami
Publikováno v:
Research in Molecular Medicine, Vol 8, Iss 4, Pp 153-162 (2020)
Background: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints and other tissues and organs of the body. Previous reports have demonstrated the imbalance of T helper (Th) subsets and Treg activity i
Externí odkaz:
https://doaj.org/article/c4bbb57ef35d4ce8b1b254c43575b885
Autor:
Reza Hajiasghar-Sharbaf, Hossein Asgarian-Omran, Reza Valadan, Hadi Hossein-Nattaj, Ramin Shekarriz, Ehsan Zaboli, Ghasem Janbabaei, Mohsen Tehrani
Publikováno v:
Iranian Journal of Allergy, Asthma and Immunology, Vol 20, Iss 6 (2021)
The role of immune checkpoint receptors in T-cell exhaustion has been demonstrated in several cancers. We investigated the co-expression of TIGIT/PD-1 and LAG-3/PD-1 cells in patients with chronic lymphocytic leukemia (CLL). The frequencies of TIGIT+
Externí odkaz:
https://doaj.org/article/357e7393c6034bdc9f8f1cc48db546de
Autor:
Zeinab Rajabian, Farzad Kalani, Saeid Taghiloo, Mohsen Tehrani, Alireza Rafiei, Zahra Hosseini-khah, Vahid Hosseini, Abolghasem Ajami
Publikováno v:
Iranian Journal of Immunology, Vol 16, Iss 1, Pp 62-70 (2019)
Externí odkaz:
https://doaj.org/article/c86ab7c199a04f9a8c4d335f92d6c688
Publikováno v:
Immunotherapy. 15:283-292
Aims: A comprehensive meta-analysis was conducted to explore the efficacy of TGF-β blockade therapies in solid tumors. Patients & methods: Results of overall survival (OS), progression-free survival (PFS), time to progression (TTP) and overall respo