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Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models.

Autor: Jaiswal S; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, La Jolla, CA 92161, USA., Cox KE; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, La Jolla, CA 92161, USA., Amirfakhri S; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, La Jolla, CA 92161, USA., Din Parast Saleh A; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA., Kobayashi K; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA., Lwin TM; Department of Surgical Oncology, City of Hope, Duarte, CA 91010, USA., Talib S; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Aithal A; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Mallya K; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Jain M; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Mohs AM; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Hoffman RM; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, La Jolla, CA 92161, USA.; AntiCancer Inc., San Diego, CA 92111, USA., Batra SK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198-5870, USA., Bouvet M; Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, La Jolla, CA 92161, USA.; UCSD Moores UCSD Cancer Center, 3855 Health Sciences Drive #0987, La Jolla, CA 92093-0987, USA.

Publikováno v: Journal of clinical medicine [J Clin Med] 2024 Oct 18; Vol. 13 (20). Date of Electronic Publication: 2024 Oct 18.

MUC16 Retention after Neoadjuvant Chemotherapy in Pancreatic Ductal Adenocarcinoma.

Autor: Muilenburg KM; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA., Ehrhorn EG; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA., Olson MT; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA., Isder CC; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA., Klute KA; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Department of Internal Medicine, University of Nebraska Medical Center, 42nd and Emile, Omaha, NE 68198, USA., Talmon GA; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, 985900 Nebraska Medical Center, Omaha, NE 68198, USA., Carlson MA; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE 68198, USA., Ly QP; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE 68198, USA., Mohs AM; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, 505 S 45 St, Omaha, NE 68198, USA.; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, S 45th St, Omaha, NE 68198, USA.

Publikováno v: Cancers [Cancers (Basel)] 2024 Oct 10; Vol. 16 (20). Date of Electronic Publication: 2024 Oct 10.

Fatty Acid Synthase Inhibitors Enhance Microtubule-Stabilizing and Microtubule-Destabilizing Drugs in Taxane-Resistant Prostate Cancer Cells.

Autor: Souchek JJ; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States., Laliwala A; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States., Houser L; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States., Muraskin L; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States., Vu Q; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States., Mohs AM; Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States.; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States.; Fred & Pamela Buffet Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198-6858, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2023 Nov 06; Vol. 6 (12), pp. 1859-1869. Date of Electronic Publication: 2023 Nov 06 (Print Publication: 2023).