Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Mohit Parekh"'
Autor:
Shazia Ashraf, Neha Deshpande, Queenie Cheung, Jeffrey Boakye Asabere, Raymond Jeff Wong, Alex G. Gauthier, Mohit Parekh, Yadav Adhikari, Geetha Melangath, Ula V. Jurkunas
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Fuchs Endothelial Corneal Dystrophy (FECD) is an aging disorder characterized by expedited loss of corneal endothelial cells (CEnCs) and heightened DNA damage compared to normal CEnCs. We previously established that ultraviolet-A (UVA) light
Externí odkaz:
https://doaj.org/article/941be83417c44d5eaca8b6a2d3809160
Autor:
Sajjad Ahmad, Vito Romano, Mohit Parekh, Stefano Ferrari, Alessandro Ruzza, Matteo Airaldi, Alexander George Wallace
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss 1 (2024)
Objective To evaluate the Descemet membrane endothelial keratoplasty (DMEK) preparation performance of trainee surgeons in an ex vivo human donor cornea DMEK wet lab simulation setting.Methods Human donor corneoscleral rims unsuitable for transplanta
Externí odkaz:
https://doaj.org/article/c5b54f8b03e54b6794929f1e5a16c975
Autor:
Nihar Bhattacharyya, Niuzheng Chai, Nathaniel J Hafford-Tear, Amanda N Sadan, Anita Szabo, Christina Zarouchlioti, Jana Jedlickova, Szi Kay Leung, Tianyi Liao, Lubica Dudakova, Pavlina Skalicka, Mohit Parekh, Ismail Moghul, Aaron R Jeffries, Michael E Cheetham, Kirithika Muthusamy, Alison J Hardcastle, Nikolas Pontikos, Petra Liskova, Stephen J Tuft, Alice E Davidson
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011230 (2024)
Fuchs endothelial corneal dystrophy (FECD) is an age-related cause of vision loss, and the most common repeat expansion-mediated disease in humans characterised to date. Up to 80% of European FECD cases have been attributed to expansion of a non-codi
Externí odkaz:
https://doaj.org/article/2483dcb3baf447028431d996808cd5cd
Autor:
Mohit Parekh, Annie Miall, Ashley Chou, Lara Buhl, Neha Deshpande, Marianne O. Price, Francis W. Price, Ula V. Jurkunas
Publikováno v:
Cells, Vol 13, Iss 14, p 1218 (2024)
Descemet’s Stripping Only (DSO) is a surgical technique that utilizes the peripheral corneal endothelial cell (CEnC) migration for wound closure. Ripasudil, a Rho-associated protein kinase (ROCK) inhibitor, has shown potential in DSO treatment; how
Externí odkaz:
https://doaj.org/article/8968e4afb16747cfb223dadd35827377
Autor:
Yalin Zheng, Francesco Aiello, Vito Romano, Luigi Fontana, Mohit Parekh, Stephen B Kaye, Diego Ponzin, Stefano Ferrari, Sorcha Ní Dhubhghaill, Vincenzo Scorcia, Kunal A Gadhvi, Hannah J Levis, Francesco Semeraro, Alessandro Ruzza, Lamis Baydoun, Björn Bachmann, Stefano Calza, Matteo Airaldi, Mor M Dickman, Antonello Moramarco, Marina Rodriguez Calvo de Mora, Carlos Rocha de Lossada, Pietro Viola
Publikováno v:
BMJ Open Ophthalmology, Vol 8, Iss 1 (2023)
Introduction The success of keratoplasty strongly depends on the health status of the transplanted endothelial cells. Donor corneal tissues are routinely screened for endothelial damage before shipment; however, surgical teams have currently no means
Externí odkaz:
https://doaj.org/article/98645f96a84a45f38cbda9bae0a1a4ed
Autor:
Tiago Ramos, Mohit Parekh, Paula Meleady, Finbarr O’Sullivan, Rosalind M. K. Stewart, Stephen B. Kaye, Kevin Hamill, Sajjad Ahmad
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The ocular surface is composed of two phenotypically and functionally different epithelial cell types: corneal and the conjunctival epithelium. Upon injury or disease, ocular surface homeostasis is impaired resulting in migration of conjunctival epit
Externí odkaz:
https://doaj.org/article/565a7f49d1b44ac6b4f243cabdae7609
Autor:
Luca Pagano, Kunal A Gadhvi, Mohit Parekh, Giulia Coco, Hannah J Levis, Diego Ponzin, Stefano Ferrari, Gianni Virgili, Stephen B Kaye, Rhiannon T Edwards, Vito Romano
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Selective lamellar corneal transplantation (keratoplasty) has overtaken full thickness penetrating keratoplasty as the graft choice for endothelial failure. Even more recently eye bank prepared tissues are becoming increasing popu
Externí odkaz:
https://doaj.org/article/d3d319aac97d4b3f9668c7b90b58a5f5
Autor:
Sara Sánchez-Tabernero, Julia Fajardo-Sanchez, Wynne Weston-Davies, Mohit Parekh, Jaime Kriman, Stephen Kaye, Sajjad Ahmad
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-6 (2021)
Abstract Purpose To evaluate the safety and preliminary efficacy of topical rVA576, a dual inhibitor of complement component 5 (C5) and leukotriene B4 (LTB4), in patients with recalcitrant atopic keratoconjunctivitis (AKC) in the open label phase 1 T
Externí odkaz:
https://doaj.org/article/6000a869e86f4ceba1b9ba4c2299cc92
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/de63a6b671154c63967ad718fe280c21
Autor:
Maan Abdullah Albarry, Mohit Parekh, Stefano Ferrari, Heba Mahmoud Eltahir, Ahmed M Shehata, Mohamed A Shaker, Hossein Mostafa Elbadawy
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Purpose: To assess the effect of different concentrations of tacrolimus eye suspension on the epithelium and stromal keratocytes of human corneas and investigate whether it can be safely used for severe cases of vernal keratoconjunctivitis (VKC).Meth
Externí odkaz:
https://doaj.org/article/9ecc1be76fbc4e0bac64d06f5dd76993