Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Mohit Lal Bhattacharyya"'
Publikováno v:
International Journal of Cardiology. 89:71-78
We tested the effects of a potassium channel opener diazoxide on the action potential duration (APD) and contractile force changes in canine Purkinje tissue induced by a novel class III anti-arrhythmic agent (C3A), KCB-328 (0.5 microM) with 3,4-dimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8dc6b2f7658912460142d4ab9b0614f
https://doi.org/10.1016/s0167-5273(02)00429-1
https://doi.org/10.1016/s0167-5273(02)00429-1
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 26:964-969
SUMMARY 1. The effects of the K+ channel opener diazoxide and the oxime-containing Ca2+ and K+ channel blocker salicylaldoxime were tested in canine cardiac Purkinje tissue. 2. Both drugs shortened action potential duration (APD). For salicylaldoxime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0a77a27e24486273a6869cc71c65c3
https://doi.org/10.1046/j.1440-1681.1999.03169.x
https://doi.org/10.1046/j.1440-1681.1999.03169.x
Publikováno v:
Journal of Molecular and Cellular Cardiology. 29:301-307
Clofilium-induced Block of Delayed Rectifier Type K + Current in Atrial Tumor Cells (AT-1 Cells). Journal of Molecular and Cellular Cardiology (1997) 29 , 301–307. Atrial tumor myocytes derived from transgenic mice (AT-1 cells) have been shown to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd0f6e069086ffd3a1d780b2aa2ac27
https://doi.org/10.1006/jmcc.1996.0275
https://doi.org/10.1006/jmcc.1996.0275
Publikováno v:
Journal of Molecular and Cellular Cardiology. 27:1931-1935
The effects of ryanodine in a cloned human cardiac potassium channel (hKvl.5) expressed in a stable mouse L cell line was studied using whole cell voltage clamp technique. Ryanodine in a dose dependent manner (10(-7) - 10(-5) M) reduced the peak curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5421cf49e716d8540b6e77b34c597c
https://doi.org/10.1016/0022-2828(95)90015-2
https://doi.org/10.1016/0022-2828(95)90015-2
Publikováno v:
International journal of cardiology. 73(1)
We studied the effects of a well known blocker (indapamide) of the slow component ( I ks ) of the delayed rectifier ( I k ) on K + currents in atrial tumor myocytes derived from transgenic mice (AT-1 cells) using one electrode voltage clamp method. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ebb8ece44ef2839c9f903a2d68c3f4
https://pubmed.ncbi.nlm.nih.gov/10748307
https://pubmed.ncbi.nlm.nih.gov/10748307
Publikováno v:
Journal of electrocardiology. 24(4)
Response of a hypoxic and acidotic (HA, with exogenous lactate) ventricular muscle tissue to subsequent reoxygenation in the absence of substrate (0 mM dextrose) was different from that of a Purkinje fiber. The K + concentration in this solution (4.6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d12839c95e77212e342cfc99c0f5ee
https://pubmed.ncbi.nlm.nih.gov/1744548
https://pubmed.ncbi.nlm.nih.gov/1744548
Publikováno v:
Journal of Electrocardiology. 22:317-324
The effects of hypoxia, hyperkalemia, and acidosis (HHA) and subsequent reoxygenation were studied in isolated canine Purkinje tissue. After 60-70 minutes of HHA, in the absence of exogenous lactate, reoxygenation reduced action potential duration (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52aff6983d48fb3e545ac7756c25d2c4
https://doi.org/10.1016/0022-0736(89)90007-1
https://doi.org/10.1016/0022-0736(89)90007-1
Publikováno v:
Journal of Electrocardiology. 21:192-197
Summary We studied slow response action potentials (SRAP) in canine ventricular muscle tissue during hypoxia (and mild acidosis) and reoxygenation. Slow responses were initiated by perfusing the tissue with a solution containing 27 mM KCl and 10 −6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af08128c90fa589d3acbab3ed7bde8d1
https://doi.org/10.1016/s0022-0736(88)80016-5
https://doi.org/10.1016/s0022-0736(88)80016-5
Publikováno v:
Biochemical and biophysical research communications. 134(2)
Summary Combined effects of hypoxia, hyperkalemia and acidosis (HH&A) produced contracture (increased resting tension) in canine ventricular muscle tissues but not in Purkinje fibers perfused for the same length of time. Administration of procaine du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708e4f1a39665baf2cd2097501e9fb2a
https://pubmed.ncbi.nlm.nih.gov/3947354
https://pubmed.ncbi.nlm.nih.gov/3947354
Publikováno v:
Journal of electrocardiology. 15(4)
Canine Purkinje and ventricular muscle fibers were superfused in vitro and the actions of tetrodotoxin (TTX, 1.56 X 10(-5) - 3.2 X 10(-7) M) on both electrical and mechanical events were studied. Tetrodotoxin reduced the amplitude of the upstroke, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2bf1ca084f7f8c58fa84f3b38a731c
https://pubmed.ncbi.nlm.nih.gov/6292321
https://pubmed.ncbi.nlm.nih.gov/6292321