Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mohit Kwatra"'
Autor:
Hongqiao Zhang, Carla D'Agostino, Christopher Tulisiak, Max A. Thorwald, Liza Bergkvist, Allison Lindquist, Lindsay Meyerdirk, Emily Schulz, Katelyn Becker, Jennifer A. Steiner, Mafalda Cacciottolo, Mohit Kwatra, Nolwen L. Rey, Martha L. Escobar Galvis, Jiyan Ma, Constantinos Sioutas, Todd E. Morgan, Caleb E. Finch, Patrik Brundin
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e15622- (2023)
Background: Epidemiological studies have variably linked air pollution to increased risk of Parkinson’s disease (PD). However, there is little experimental evidence for this association. Alpha-synuclein (α-syn) propagation plays central roles in P
Externí odkaz:
https://doaj.org/article/2cb7b45f11bf473183868a0bdea5ceb7
Publikováno v:
Cells, Vol 11, Iss 23, p 3736 (2022)
The most commonly used treatment for Parkinson’s disease (PD) is levodopa, prescribed in conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement therapy using levodopa during the course of the disease’s progression
Externí odkaz:
https://doaj.org/article/21029c9964ad41cd9a68aaf2d7cacad4
Publikováno v:
ACS Chemical Neuroscience. 13:53-68
NLRP3 activation plays a key role in the initiation and progression of a variety of neurodegenerative diseases. However, understanding the molecular mechanisms involved in the bidirectional signaling required to activate the NLRP3 inflammasomes is th
Autor:
Paritosh Parashar, B Prabhakar, Sonali Swain, Nisha Adhikari, Punit Aryan, Anupama Singh, Mohit Kwatra
Publikováno v:
Antiviral research. 203
Monoclonal antibodies (mAbs) that are specific to SARS-CoV-2 can be useful in diagnosing, preventing, and treating the coronavirus (COVID-19) illness. Strategies for the high-throughput and rapid isolation of these potent neutralizing antibodies are
Publikováno v:
Brain : a journal of neurology. 145(4)
This scientific commentary refers to ‘Prion-like α-synuclein pathology in the brain of infants with Krabbe disease’ by Hatton et al. (https://doi.org/10.1093/brain/awac002).
Publikováno v:
Chemico-Biological Interactions. 364:110039
The current study aimed to validate the mice model of alcohol (ALC), high-fat diet (HFD), and HFD + ALC combination affecting neurobehavioral and neurochemical anomalies via inflammatory cascade, lowered neurogenesis, enhanced microgliosis, reactive
Several activators of NLRP3 inflammasome have been described; however, the central mechanisms of NLRP3 inflammasome activation in brain microglia, especially at the activating step through free radical generation, still require further clarification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ac6502ed7cb2532d2aa80c5d6d4ea56
https://doi.org/10.21203/rs.3.rs-260478/v1
https://doi.org/10.21203/rs.3.rs-260478/v1
Publikováno v:
Background and Management of Muscular Atrophy ISBN: 9781838807245
Muscles are the enriched reservoir of proteins in the body. During any workout or exercise, the demand in the form of energy is essentially required by the muscle. Energy expenditure of skeletal muscle is more dependent on the type of demand. There i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a3cb63ed3e86e92da083b55bd44ed4
http://www.intechopen.com/articles/show/title/molecular-mechanisms-therapeutic-targets-and-pharmacological-interventions-an-update
http://www.intechopen.com/articles/show/title/molecular-mechanisms-therapeutic-targets-and-pharmacological-interventions-an-update
Autor:
P. A. Shantanu, Vegi Ganga Modi Naidu, Vijaya Kumar Gangipangi, Basveshwar Gawali, Nitika Gupta, Sahabuddin Ahmed, Mohit Kwatra, Samir Ranjan Panda
Publikováno v:
Journal of psychiatric research. 144
Major depressive disorder (MDD) is the foremost leading psychiatric illness prevailing around the globe. It usually exists along with anxiety and other clinical conditions (cardiovascular, cancer, neurodegenerative diseases, and infectious diseases).
Publikováno v:
Apoptosis : an international journal on programmed cell death. 26(1-2)
Striatal neurons depends on an afferent supply of brain-derived neurotrophic factor-(BDNF) that explicitly interacts with tropomyosin receptor kinase B (TrkB) receptor and performs sundry functions including synaptic plasticity, neuronal differentiat