Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Mohini S"'
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 5, Pp 1950-1955 (2024)
Context: Adolescent phase is a very crucial period in one’s life, much emotional and psychological support is needed for an adolescent to bloom into a responsible adult. But unfortunately adolescents do not get the support or they fail to seek supp
Externí odkaz:
https://doaj.org/article/4e6ba8c816554e0e83b955f2536987e0
Autor:
Rana T. Alhashimi, Tarek A. Ahmed, Lamya Alghanem, Piyusha P. Pagare, Boshi Huang, Mohini S. Ghatge, Abdelsattar M. Omar, Osheiza Abdulmalik, Yan Zhang, Martin K. Safo
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2547 (2023)
The synthetic allosteric effector of hemoglobin, TD-7 has been investigated as a potential therapeutic agent for the treatment of sickle cell disease. The pharmacologic activity of TD-7 is due to formation of a Schiff-base interaction between its ald
Externí odkaz:
https://doaj.org/article/e5e641785d274cb6a088cd67b1ee01dc
Autor:
Boshi Huang, Mohini S. Ghatge, Akua K. Donkor, Faik N. Musayev, Tanvi M. Deshpande, Mohammed Al-Awadh, Rana T. Alhashimi, Hongmei Zhu, Abdelsattar M. Omar, Marilyn J. Telen, Yan Zhang, Tim J. McMahon, Osheiza Abdulmalik, Martin K. Safo
Publikováno v:
Molecules, Vol 27, Iss 20, p 6835 (2022)
Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the dis
Externí odkaz:
https://doaj.org/article/065bb1f3e66e489a8d47e684c10f8021
Autor:
Rana T. Alhashimi, Mohini S. Ghatge, Akua K. Donkor, Tanvi M. Deshpande, Nancy Anabaraonye, Dina Alramadhani, Richmond Danso-Danquah, Boshi Huang, Yan Zhang, Faik N. Musayev, Osheiza Abdulmalik, Martin K. Safo
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 696 (2022)
5-hydroxyfurfural (5HMF), an allosteric effector of hemoglobin (Hb) with an ability to increase Hb affinity for oxygen has been studied extensively for its antisickling effect in vitro and in vivo, and in humans for the treatment of sickle cell disea
Externí odkaz:
https://doaj.org/article/e86fec00e2774e248bc84f858cb480f1
Autor:
Ganesh N Dakhale, Sumit S Wankhede, Mohini S Mahatme, Sachin K Hiware, Dharmendra B Mishra, Sujata S Dudhgaonkar
Publikováno v:
Indian Journal of Dermatology, Vol 61, Iss 1, Pp 63-69 (2016)
Objective: To compare efficacy, safety and cost-effectiveness of rupatadine and olopatadine in patients of chronic spontaneous urticaria. Materials and Methods: A 6-week, single-centered, randomized, double blind, parallel group comparative clinical
Externí odkaz:
https://doaj.org/article/3fee9beb20684af9983f6ee7d27e6a51
Autor:
Abdelsattar M. Omar, Osheiza Abdulmalik, Mohini S. Ghatge, Yosra A. Muhammad, Steven D. Paredes, Moustafa E. El-Araby, Martin K. Safo
Publikováno v:
Biomolecules, Vol 10, Iss 11, p 1508 (2020)
Aromatic aldehydes that bind to sickle hemoglobin (HbS) to increase the protein oxygen affinity and/or directly inhibit HbS polymer formation to prevent the pathological hypoxia-induced HbS polymerization and the subsequent erythrocyte sickling have
Externí odkaz:
https://doaj.org/article/b3322b5bdc3b4c949d8736deafb25c05
Autor:
Abdelsattar M. Omar, Mona A. Mahran, Mohini S. Ghatge, Faida H. A. Bamane, Mostafa H. Ahmed, Moustafa E. El-Araby, Osheiza Abdulmalik, Martin K. Safo
Publikováno v:
Molecules, Vol 21, Iss 8, p 1057 (2016)
Hemoglobin (Hb) modifiers that stereospecifically inhibit sickle hemoglobin polymer formation and/or allosterically increase Hb affinity for oxygen have been shown to prevent the primary pathophysiology of sickle cell disease (SCD), specifically, Hb
Externí odkaz:
https://doaj.org/article/7f3fe13dd71643c7b1ead45220de5895
Autor:
Amit K Gandhi, Jigar V Desai, Mohini S Ghatge, Martino L di Salvo, Stefano Di Biase, Richmond Danso-Danquah, Faik N Musayev, Roberto Contestabile, Verne Schirch, Martin K Safo
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40954 (2012)
Several drugs and natural compounds are known to be highly neurotoxic, triggering epileptic convulsions or seizures, and causing headaches, agitations, as well as other neuronal symptoms. The neurotoxic effects of some of these compounds, including t
Externí odkaz:
https://doaj.org/article/59c7c18da118465ba193a6194bf54281
Autor:
Mohini S Ghatge, Roberto Contestabile, Martino L di Salvo, Jigar V Desai, Amit K Gandhi, Christina M Camara, Rita Florio, Isabel N González, Alessia Parroni, Verne Schirch, Martin K Safo
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41680 (2012)
Pyridoxal 5'-phosphate (PLP) is a cofactor for dozens of B(6) requiring enzymes. PLP reacts with apo-B(6) enzymes by forming an aldimine linkage with the ε-amino group of an active site lysine residue, thus yielding the catalytically active holo-B(6
Externí odkaz:
https://doaj.org/article/120dee9975ab43af9abb54d72c3321d4
Autor:
Sundaram, Hemamalini1, Jogdand, Mohini S.1 mohinijogdand@gmail.com, Sambutwad, Rajesh C.1, Sirsulwar, Ganesh K.1
Publikováno v:
Journal of Family Medicine & Primary Care. May2024, Vol. 13 Issue 5, p1950-1955. 6p.