Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mohini Gray"'
Autor:
Elinor Wing, Catherine Sutherland, Katherine Miles, David Gray, Carl S. Goodyear, Thomas D. Otto, Stefan Breusch, Graeme Cowan, Mohini Gray
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
B cells are key pathogenic drivers of chronic inflammation in rheumatoid arthritis (RA). There is limited understanding of the relationship between synovial B cell subsets and pathogenic antibody secreting cells (ASCs). This knowledge is crucial for
Externí odkaz:
https://doaj.org/article/7be81bbfafaa40f7b7970a61171c4912
Autor:
Graeme J. M. Cowan, Katherine Miles, Lorenzo Capitani, Sophie S. B. Giguere, Hanna Johnsson, Carl Goodyear, Iain B. McInnes, Steffen Breusch, David Gray, Mohini Gray
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
B cells are critical for promoting autoimmunity and the success of B cell depletion therapy in rheumatoid arthritis (RA) confirms their importance in driving chronic inflammation. Whilst disease specific autoantibodies are useful diagnostically, our
Externí odkaz:
https://doaj.org/article/0e48b0fffc664e8ba6b84de7f262ee22
Autor:
Emily Gwyer Findlay, Andrew J. Currie, Ailiang Zhang, Jana Ovciarikova, Lisa Young, Holly Stevens, Brian J. McHugh, Marta Canel, Mohini Gray, Simon W.F. Milling, John D.M. Campbell, John Savill, Alan Serrels, Donald J. Davidson
Publikováno v:
OncoImmunology, Vol 8, Iss 8 (2019)
Immunization of patients with autologous, ex vivo matured dendritic cell (DC) preparations, in order to prime antitumor T-cell responses, is the focus of intense research. Despite progress and approval of clinical approaches, significant enhancement
Externí odkaz:
https://doaj.org/article/8c619a0ba3fa49a6a60740bf5be1c638
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
The chronic autoimmune inflammatory diseases, systemic lupus erythematosus and Sjogren’s syndrome, develop when tolerance to apoptotic cells (ACs) is lost. We have previously reported that this tolerance is maintained by innate-like, IL-10 secretin
Externí odkaz:
https://doaj.org/article/c5f4ae7392444d8496974b080cdf00cf
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Plasmacytoid dendritic cells (pDCs) play a pivotal role in driving the autoimmune disease systemic lupus erythematosus, via the secretion of IFNα in response to nuclear self-antigens complexed with auto-antibodies. Apoptotic cells, generated at site
Externí odkaz:
https://doaj.org/article/c841d649afa64613ba7642deebffed0b
Autor:
Agnes E Coutinho, Jeremy K Brown, Fu Yang, David G Brownstein, Mohini Gray, Jonathan R Seckl, John S Savill, Karen E Chapman
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54640 (2013)
Mast cells are key initiators of allergic, anaphylactic and inflammatory reactions, producing mediators that affect vascular permeability, angiogenesis and fibrosis. Glucocorticoid pharmacotherapy reduces mast cell number, maturation and activation b
Externí odkaz:
https://doaj.org/article/ec5a20e5f24d44f185911da8a047997d
Autor:
Jana Ovciarikova, Mohini Gray, Donald J. Davidson, Alan Serrels, Marta Canel, Emily Gwyer Findlay, Andrew J. Currie, Holly Stevens, Simon Milling, Brian J. McHugh, Lisa Young, John D.M. Campbell, Ailiang Zhang, John Savill
Publikováno v:
Findlay, E G, Currie, A J, Zhang, A, Ovciarikova, J, Young, L, Stevens, H, McHugh, B J, Canel, M, Gray, M, Milling, S W F, Campbell, J D M, Savill, J, Serrels, A & Davidson, D J 2019, ' Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy ', OncoImmunology, pp. 1-17 . https://doi.org/10.1080/2162402X.2019.1608106
Oncoimmunology
OncoImmunology, Vol 8, Iss 8 (2019)
Oncoimmunology
OncoImmunology, Vol 8, Iss 8 (2019)
Immunization of patients with autologous, ex vivo matured dendritic cell (DC) preparations, in order to prime antitumor T-cell responses, is the focus of intense research. Despite progress and approval of clinical approaches, significant enhancement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce3ab845655c26e5b3268b8b8a280b0
https://hdl.handle.net/20.500.11820/736001b6-f7c0-4385-86c4-0726b976c9b6
https://hdl.handle.net/20.500.11820/736001b6-f7c0-4385-86c4-0726b976c9b6
Autor:
Jack Satsangi, Ray Boyapati, Nicholas T. Ventham, Mary K. Doherty, Philip D. Whitfield, Gwo-Tzer Ho, Mohini Gray, Joseph Loane, Rahul Kalla, Arina Tamborska, Adriano G. Rossi, David A. Dorward
Publikováno v:
Boyapati, R K, Dorward, D A, Tamborska, A, Kalla, R, Ventham, N T, Doherty, M K, Whitfield, P D, Gray, M, Loane, J, Rossi, A G, Satsangi, J & Ho, G-T 2018, ' Mitochondrial DNA Is a Pro-Inflammatory Damage-Associated Molecular Pattern Released During Active IBD ', Inflammatory Bowel Diseases . https://doi.org/10.1093/ibd/izy095, https://doi.org/10.1093/ibd/izy095
Inflamm Bowel Dis
Inflamm Bowel Dis
Background Due to common evolutionary origins, mitochondrial DNA (mtDNA) shares many similarities with immunogenic bacterial DNA. MtDNA is recognized as a pro-inflammatory damage-associated molecular pattern (DAMP) with a pathogenic role in several i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e58a78bd79c17364e5d2af8aa2f45a
https://www.pure.ed.ac.uk/ws/files/64213510/CLEAN_RE.DOC
https://www.pure.ed.ac.uk/ws/files/64213510/CLEAN_RE.DOC
Autor:
Saba Nayar, Marc Veldhoen, Kyoko Nakamura, Sergei A. Nedospasov, Mohini Gray, Cécile Bénézech, Judith E. Allen, Andrew N. J. McKenzie, Jennifer L. Marshall, Lucy H. Jones, Jennifer A. Walker, Alistair McIntosh, Adriana Flores-Langarica, Nguyet-Thin Luu, Francesca Barone, George Kollias, Kai-Michael Toellner, Gurdyal S. Besra, Katherine Miles, Nick D. Jones, David R. Withers, Andrei A. Kruglov, Yunhua Loo, Jorge Caamano, Yang Zhang, Adam F. Cunningham
Publikováno v:
Bénézech, C, Luu, N-T, Walker, J A, Kruglov, A, Loo, Y, Nakamura, K, Zhang, Y, Nayar, S, Jones, L H, Flores-Langarica, A, McIntosh, A, Marshall, J, Barone, F, Besra, G, Miles, K, Allen, J E, Gray, M, Kollias, G, Cunningham, A F, Withers, D R, Toellner, K-M, Jones, N, Veldhoen, M, Nedospasov, S A, McKenzie, A N J & Caamano, J H 2015, ' Inflammation-induced formation of fat-associated lymphoid clusters ', Nature Immunology, vol. 16, no. 8, pp. 819–828 . https://doi.org/10.1038/ni.3215
Nat Immunol 16(8) 819-28 (2015)
Nature immunology
ZENODO
Europe PubMed Central
Nat Immunol 16(8) 819-28 (2015)
Nature immunology
ZENODO
Europe PubMed Central
Fat-associated lymphoid clusters (FALCs) are a type of lymphoid tissue associated with visceral fat. Here we found that the distribution of FALCs was heterogeneous, with the pericardium containing large numbers of these clusters. FALCs contributed to
Autor:
Sarah L, McGlasson, Fiona, Semple, Heather, MacPherson, Mohini, Gray, Donald J, Davidson, Julia R, Dorin
Publikováno v:
European Journal of Immunology
Human β‐defensin 3 (hBD3) is a cationic antimicrobial peptide with potent bactericidal activity in vitro. HBD3 is produced in response to pathogen challenge and can modulate immune responses. The amplified recognition of self‐DNA by human plasma