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of 5
pro vyhledávání: '"Mohd Tayyab Adil"'
Autor:
Kenji Kamimoto, Mohd Tayyab Adil, Kunal Jindal, Christy M. Hoffmann, Wenjun Kong, Xue Yang, Samantha A. Morris
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 97-112 (2023)
Summary: In direct lineage conversion, transcription factor (TF) overexpression reconfigures gene regulatory networks (GRNs) to reprogram cell identity. We previously developed CellOracle, a computational method to infer GRNs from single-cell transcr
Externí odkaz:
https://doaj.org/article/36245da6adcd4d28ba8dbd971ef7232b
Autor:
Kunal Jindal, Mohd Tayyab Adil, Naoto Yamaguchi, Xue Yang, Helen C. Wang, Kenji Kamimoto, Guillermo C. Rivera-Gonzalez, Samantha A. Morris
Complex gene regulatory mechanisms underlie differentiation and reprogramming. Contemporary single-cell lineage tracing (scLT) methods use expressed, heritable DNA barcodes to combine cell lineage readout with single-cell transcriptomics enabling hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbeb4c5cd2a39fb5de0ec2c3ed93cf2b
https://doi.org/10.1101/2022.10.23.512790
https://doi.org/10.1101/2022.10.23.512790
Autor:
Kenji Kamimoto, Mohd Tayyab Adil, Kunal Jindal, Christy M. Hoffmann, Wenjun Kong, Xue Yang, Samantha A. Morris
SummaryIn direct lineage reprogramming, transcription factor (TF) overexpression reconfigures Gene Regulatory Networks (GRNs) to convert cell identities between fully differentiated cell types. We previously developed CellOracle, a computational pipe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f43b8f48de045bcb21df4529d0bc2f
https://doi.org/10.1101/2022.07.01.497374
https://doi.org/10.1101/2022.07.01.497374
Autor:
Mohd Tayyab Adil, Jonathan J. Henry
Publikováno v:
Genesis (New York, N.Y. : 2000)REFERENCES. 59(1-2)
Animal models have contributed greatly to our understanding of human diseases. Here, we focus on cornea epithelial stem cell (CESC) deficiency (commonly called limbal stem cell deficiency, LSCD). Corneal development, homeostasis and wound healing are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa93e5f7431e6851ff9dfc18a3bd951a
https://pubmed.ncbi.nlm.nih.gov/33576188
https://pubmed.ncbi.nlm.nih.gov/33576188
PURPOSEXenopushas the remarkable ability to regenerate a lens from the basal cornea epithelial cells in response to signals from the retina. Previous work demonstrated that the Retinoic Acid (RA) metabolizing enzyme CYP26 is expressed in the cornea,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a5bf9b79388d56f21b80368a405253