Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mohd Khairul Nizam, Mohd Khalid"'
Autor:
Zahidah Abu Seman, Fadly Ahid, Nor Rizan Kamaluddin, Ermi Neiza Mohd Sahid, Ezalia Esa, Siti Shahrum Muhamed Said, Norazlina Azman, Wan Khairull Dhalila Wan Mat, Julia Abdullah, Nurul Aqilah Ali, Mohd Khairul Nizam Mohd Khalid, Yuslina Mat Yusoff
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Objective Mutational analysis of BCR::ABL1 kinase domain (KD) is a crucial component of clinical decision algorithms for chronic myeloid leukemia (CML) patients with failure or warning responses to tyrosine kinase inhibitor (TKI) therapy. Th
Externí odkaz:
https://doaj.org/article/ec23452a481e4309b0f21ac9bb3102d4
Autor:
Mei-Yan Chan, Julaina Abdul Jalil, Yusnita Yakob, Siti Aishah Abdul Wahab, Ernie Zuraida Ali, Mohd Khairul Nizam Mohd Khalid, Huey-Yin Leong, Hui-Bein Chew, Jeya Bawani Sivabalakrishnan, Lock-Hock Ngu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Pompe disease is a rare glycogen storage disorder caused by deficiency of the lysosomal enzyme acid alpha-glucosidase (GAA), leading to glycogen deposition in multiple tissues. Infantile-onset Pompe disease (IOPD) patients present
Externí odkaz:
https://doaj.org/article/4d80c9ff956948ffb92f6bbfcbd5b9cb
Autor:
Jeyanthi Suppiah, Ernie Zuraida Ali, Mohd Khairul Nizam Mohd Khalid, Sumarni Mohd Ghazali, Kok Keng Tee, Murni Maya Sari Zulkifli, Nuraisyah Ramli, Amir Hussin Adiee, Muhamad Nurrani Ramly, Fionie Robert, Sarbhan Singh Lakha Singh, Rozainanee Mohd Zain, Ravindran Thayan
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 8, p 409 (2023)
Dengue virus serotype 4 (DENV-4) has been the rarest circulating serotype in Malaysia, resulting in it being an understudied area. A recent observation from institutional surveillance data indicated a rapid increase in DENV-4-infected cases. The pres
Externí odkaz:
https://doaj.org/article/8ba5577daf164c54aa5fabbad437dc2a
Autor:
Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Qi Wang, Jacqueline K. R. Walker, Grace E. Lidgerwood, Kimberley L. Dilworth, Leszek Lisowski, Alice Pébay, Alex W. Hewitt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Off-target effects and the feasibility for AAV-mediated delivery are the major barriers impeding the clinical in vivo application of base editors. Here, the authors report the small size AAV-deliverable Cas9-ABE variant that has improved on-target ed
Externí odkaz:
https://doaj.org/article/e11fbcac1a274b3aa056ddd2fd2f8176
Autor:
Siti Aishah Abdul Wahab, Yusnita Yakob, Mohd Khairul Nizam Mohd Khalid, Noraishah Ali, Huey Yin Leong, Lock Hock Ngu
Publikováno v:
Genetics Research, Vol 2022 (2022)
Background. Glycogen storage disease type 1a (GSD1a) is a rare autosomal recessive metabolic disorder characterized by hypoglycaemia, growth retardation, lactic acidosis, hepatomegaly, hyperlipidemia, and nephromegaly. GSD1a is caused by a mutation i
Externí odkaz:
https://doaj.org/article/22f071b3008a432793afed0b343a722e
Application of Multilocus Sequence Typing for the Characterization of Leptospira Strains in Malaysia
Autor:
Fairuz Amran, Nurul Atiqah Noor Halim, Ayu Haslin Muhammad, Mohd Khairul Nizam Mohd Khalid, Nur Mukmina Dasiman, Nadia Aqilla Shamsusah, Abdul Khalif Adha Abd Talib, Mohamed Asyraf Noh, Mohammad Ridhuan Mohd Ali, Rohaidah Hashim
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 8, Iss 2, p 69 (2023)
Leptospirosis is a common zoonotic disease in tropical and subtropical countries. It is considered an emerging disease in Malaysia and is a notifiable disease. This study was conducted to characterize Malaysian isolates from human, animal and environ
Externí odkaz:
https://doaj.org/article/7e0fea14a2b947a392a264671d1e2793
Autor:
Huey Yin Leong, Nor Azimah Abdul Azize, Hui Bein Chew, Wee Teik Keng, Meow Keong Thong, Mohd Khairul Nizam Mohd Khalid, Liang Choo Hung, Norzila Mohamed Zainudin, Azura Ramlee, Muzhirah Aisha Md Haniffa, Yusnita Yakob, Lock Hock Ngu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Background Mucopolysaccharidosis IVA (MPS IVA) is an autosomal recessive lysosomal storage disease due to N-acetylgalactosamine-6-sulfatase (GALNS) deficiency. It results in accumulation of the glycosaminoglycans, keratan sulfate and chondro
Externí odkaz:
https://doaj.org/article/3ceceb60b033493d83a1a1fe11a77f3f
Autor:
Minh Thuan Nguyen Tran, Mohd Khairul Nizam Mohd Khalid, Alice Pébay, Anthony L. Cook, Helena H. Liang, Raymond C.B. Wong, Jamie E. Craig, Guei-Sheung Liu, Sandy S. Hung, Alex W. Hewitt
Publikováno v:
Molecular Vision, Vol 25, Iss 1, Pp 174-182 (2019)
Purpose: To evaluate the efficacy of using a CRISPR/Cas-mediated strategy to correct a common high-risk allele that is associated with age-related macular degeneration (AMD; rs1061170; NM_000186.3:c.1204T>C; NP_000177.2:p.His402Tyr) in the complement
Externí odkaz:
https://doaj.org/article/e430164dd6c74de4a5a521b0a32ca43d
Autor:
Shirley Yi Fen Hii, Norazah Ahmad, Rohaidah Hashim, Yii Ling Liow, Muhammad Adib Abd Wahab, Mohd Khairul Nizam Mohd Khalid
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-8 (2018)
Abstract Objective There is a lack of study in Corynebacterium diphtheriae isolates in Malaysia. The alarming surge of cases in year 2016 lead us to evaluate the local clinical C. diphtheriae strains in Malaysia. We conducted single nucleotide polymo
Externí odkaz:
https://doaj.org/article/fe167cc221d348b083522d1f8845e93c
Autor:
Antony T Vincent, Olivier Schiettekatte, Cyrille Goarant, Vasantha Kumari Neela, Eve Bernet, Roman Thibeaux, Nabilah Ismail, Mohd Khairul Nizam Mohd Khalid, Fairuz Amran, Toshiyuki Masuzawa, Ryo Nakao, Anissa Amara Korba, Pascale Bourhy, Frederic J Veyrier, Mathieu Picardeau
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007270 (2019)
The causative agents of leptospirosis are responsible for an emerging zoonotic disease worldwide. One of the major routes of transmission for leptospirosis is the natural environment contaminated with the urine of a wide range of reservoir animals. S
Externí odkaz:
https://doaj.org/article/c19955a4a0094b5ab36b6f3f216e55b6