Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mohannad Idress"'
Autor:
Mohannad Idress, Bruce F. Milne, Gary S. Thompson, Laurent Trembleau, Marcel Jaspars, Wael E. Houssen
Publikováno v:
Molecules, Vol 25, Iss 4, p 922 (2020)
As opposed to small molecules, macrocyclic peptides possess a large surface area and are recognised as promising candidates to selectively treat diseases by disrupting specific protein−protein interactions (PPIs). Due to the difficulty in predictin
Externí odkaz:
https://doaj.org/article/36b91441d62b40bbbd67e465be981511
Autor:
Alessandro Colombano, Luca Dalponte, Sergio Dall'Angelo, Claudia Clemente, Mohannad Idress, Ahmad Ghazal, Wael E. Houssen
Publikováno v:
Angewandte Chemie. 135
Autor:
Bruce F. Milne, Gary S. Thompson, Wael E. Houssen, Laurent Trembleau, Mohannad Idress, Marcel Jaspars
Publikováno v:
Molecules
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 922 (2020)
Volume 25
Issue 4
Molecules, Vol 25, Iss 4, p 922 (2020)
As opposed to small molecules, macrocyclic peptides possess a large surface area and are recognised as promising candidates to selectively treat diseases by disrupting specific protein&ndash
protein interactions (PPIs). Due to the difficulty in
protein interactions (PPIs). Due to the difficulty in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea300bfcc523a77ff833a2f4e59f5ae
https://kar.kent.ac.uk/80542/1/molecules-25-00922.pdf
https://kar.kent.ac.uk/80542/1/molecules-25-00922.pdf
Autor:
Wael E. Houssen, David P. Fewer, Cristina N. Alexandru-Crivac, Christian Umeobika, Kaarina Sivonen, Jouni Jokela, Laurent Trembleau, Niina Leikoski, Eike Siebs, Matti Wahlsten, Mohannad Idress, Peter Sjö, André M. Grilo, Ada F. Nneoyiegbe, Marcel Jaspars, Alleyn T. Plowright, Kirstie A. Rickaby
Publikováno v:
Chemical Communications. 53:10656-10659
Macrocyclic peptides have promising therapeutic potential but the scaling up of their chemical synthesis is challenging. The cyanobactin macrocyclase PatGmac is an efficient tool for production but is limited to substrates containing 6–11 amino aci
Autor:
Cristina N. Alexandru-Crivac, Luca Dalponte, Wael E. Houssen, Mohannad Idress, Kirstie A. Rickaby, Laurent Trembleau, Marcel Jaspars
This chapter sums up the different approaches to harness the promising therapeutic potential of cyclic peptides in drug discovery and proposes a number of areas which need improvement in order to make cyclic peptides live up to their full potential a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d0b95d038cc57983fae31de3681e1d
https://doi.org/10.1039/9781788010153-00340
https://doi.org/10.1039/9781788010153-00340
Publikováno v:
Journal of Applied Pharmacy. 7
This study is aimed at exploring the potential of developing naturally occurring L-glutaminase isolated from green chilies as anti-leukemic drug which selectively targets cancer cell metabolism unlike other nonselective chemotherapeutics. This was do