Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Mohane Selvaraj Coumar"'
Publikováno v:
ACS Omega, Vol 6, Iss 9, Pp 6100-6111 (2021)
Externí odkaz:
https://doaj.org/article/65db0cff8d534eef83d7b1080d45e4f8
Autor:
Mu-Chun Li, Mohane Selvaraj Coumar, Shu-Yu Lin, Yih-Shyan Lin, Guan-Lin Huang, Chun-Hwa Chen, Tzu-Wen Lien, Yi-Wen Wu, Yen-Ting Chen, Ching-Ping Chen, Yu-Chen Huang, Kai-Chia Yeh, Chen-Ming Yang, Bikashita Kalita, Shiow-Lin Pan, Tsu-An Hsu, Teng-Kuang Yeh, Chiung-Tong Chen, Hsing-Pang Hsieh
Publikováno v:
Journal of Medicinal Chemistry. 66:2566-2588
Autor:
Gollagani Vijaya Bhavani, Sree Karani Kondapuram, Aifa Fathima Shamsudeen, Mohane Selvaraj Coumar, Joseph Selvin, Tharanikkarasu Kannan
Publikováno v:
Drug Development Research. 84:500-513
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer
Autor:
Safiulla Basha Syed, Hemant Arya, I-Hsuan Fu, Teng-Kuang Yeh, Latha Periyasamy, Hsing-Pang Hsieh, Mohane Selvaraj Coumar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract P-glycoprotein (P-gp) is a drug transporter that effluxes chemotherapeutic drugs and is implicated in the development of resistance of cancer cells to chemotherapeutic drugs. To date, no drug has been approved to inhibit P-gp and restore che
Externí odkaz:
https://doaj.org/article/8f1abc9fc04a4f1dbd447a375a78af9c
Autor:
G.B. Priyadharshini, C. Jaynthy, Sree Karani Kondapuram, George Seghal Kiran, Mohane Selvaraj Coumar, Joseph Selvin
Publikováno v:
Biochemical and Biophysical Research Communications.
Publikováno v:
Cellular Oncology. 44:751-775
The transition of a primary tumour to metastatic progression is driven by dynamic molecular changes, including genetic and epigenetic alterations. The metastatic cascade involves bidirectional interactions among extracellular and intracellular compon
Autor:
Hsu Yi Sun, Na Sun, Hsing Pang Hsieh, Julakanti Satyanarayana Reddy, Chih Ming Chen, Mohane Selvaraj Coumar
Publikováno v:
Organic Process Research & Development. 25:817-830
Herein, a robust and scalable procedure for the synthesis of multikinase inhibitor BPR1K871 (1, a quinazoline compound bearing a substituted thiazoline side chain), which is a clinical candidate fo...
Autor:
Mohane Selvaraj Coumar, Sailu Sarvagalla, Cheemala Ashok, Phani Krishna Parcha, Baskaran Rajasekaran, S.J.Sudharshan, Madhu Dyavaiah
Publikováno v:
Pharmacological Reports. 73:615-628
Papaverine is a benzylisoquinoline alkaloid from the plant Papaver somniferum (Opium poppy). It is approved as an antispasmodic drug by the US FDA and is also reported to have anti-cancer properties. Here, Papaverine's activity in chronic myeloid leu
Publikováno v:
Gene. 844
Identifying suitable deregulated targets in autophagy pathway is essential for developing autophagy modulating cancer therapies. With this aim, we systematically analyzed the expression levels of genes that contribute to the execution of autophagy in
Autor:
Arunkumar Dhayalan, Mohane Selvaraj Coumar, Hsing Pang Hsieh, Shu Yu Lin, M. Ramya Chandar Charles, Arun Mahesh
Publikováno v:
Biochimie. 168:220-230
G9a (also known as EHMT2 - Euchromatin histone methyltransferase 2) is a protein lysine methyltransferase which introduces methylation modification in variety of proteins including histones. G9a catalyzes the dimethylation of lysine 9 on histone 3 (H