The Carbonic Anhydrase Inhibitor E7070 Sensitizes Glioblastoma Cells to Radio- and Chemotherapy and Reduces Tumor Growth

Autor: Luiz Gonzaga Tone, Mariano S. Viapiano, Julia Alejandra Pezuk, Silvia A. Teixeira, Augusto Faria Andrade, Mohan Sobhana Nandhu, Luciano Neder, Carlos Gilberto Carlotti, Carlos Alberto Scrideli, Aline Paixão Becker, Lucas T Bidinotto, Veridiana K. Suazo

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Made available in DSpace on 2021-06-25T11:03:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Glioblastomas (GBMs), the most common and lethal primary brain tumor, show inherent infiltrative nature and high molecular heterogeneity that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830d3520dfdf8fa34d42a92bc21435a8

Abstract 3148: A novel mechanism of glioblastoma cell invasion regulated by a neural proteoglycan that activates Src/EGFR signaling and mediates tumor-astroglia cooperation

Autor: Bin Hu, Mariano S. Viapiano, Mohan Sobhana Nandhu, Russell T. Matthews, Somanath Kundu, Hosung Sim

Publikováno v: Cancer Research. 81:3148-3148

The goal of this study was to investigate a novel mechanism by which neural extracellular matrix (ECM) proteins regulate the invasive behavior of malignant gliomas, which are the most common primary brain tumors in adults. Invasion of glioma cells is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94b8068ff8c133255a03dbb2c09471e3
https://doi.org/10.1158/1538-7445.am2021-3148

IMMU-39. FIRST-IN-KIND T CELLS CARRYING A CHIMERIC ANTIGEN RECEPTOR AGAINST AN EXTRACELLULAR MATRIX PROTEIN TARGET GLIOBLASTOMA CELLS AND SHOW ANTI-TUMOR EFFICACY

Autor: Sadhak Sengupta, Mariano S. Viapiano, John Longo, Mohan Sobhana Nandhu, Sharon L. Longo, Sudarshana Sengupta, Prakash Sampath

Immunotherapies using engineered T lymphocytes expressing chimeric antigen receptors (CAR-T cells) are showing great promise against glioblastoma but are still limited by the escape of antigen-deficient clones and by inefficient latching of the T cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c560891da474d477bde18edcae97fb5
https://europepmc.org/articles/PMC6216372/

TMIC-48. REGULATION OF THE PROTEASE ADAM17 BY EXTRACELLULAR SIGNALS DRIVES PRO-TUMORAL PROGRAMS IN GLIOBLASTOMA CELLS AND THEIR MICROENVIRONMENT

Autor: Bin Hu, Mohan Sobhana Nandhu, Mariano S. Viapiano, Vivek Bhaskaran

The cell-surface metalloprotease ADAM17/TACE regulates multiple signaling cascades, such as Notch and NFkB, which are critical for glioblastoma (GBM) growth and invasion. This enzyme is tonically inhibited by the extracellular matrix (ECM)-associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5186d34b4ec11d7d79191304c9edaa0
https://europepmc.org/articles/PMC5692266/

Angle correction for small animal tumor imaging with spatial frequency domain imaging (SFDI)

Autor: Syeda Tabassum, Yanyu Zhao, Mariano S. Viapiano, Mohan Sobhana Nandhu, Darren Roblyer, Shaheer Piracha

Spatial frequency domain imaging (SFDI) is a widefield imaging technique that allows for the quantitative extraction of tissue optical properties. SFDI is currently being explored for small animal tumor imaging, but severe imaging artifacts occur for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4ef8bb5cad568ebad3369de381d5ca
https://europepmc.org/articles/PMC4918590/