Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mohan Kocherla"'
Autor:
Jovaniel Rodriguez-Maldonado, James S. Graydon, Mohan Kocherla, Seth Baker, Karla Claudio, Gualberto Ruaño, Abiel Roche-Lima, Mark Ferreira, Jorge Duconge
Publikováno v:
Biomarkers in Medicine. 13:649-661
Aim: Variants of the MTHFR gene have been associated with a wide range of diseases. Materials & methods: The present study analyzed data from clinical genotyping of MTHFR 677C>T and 1298A>C in 1405 patients in urban primary care settings. Results: St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a929a0776702dc0b36bfad323d0a390c
https://doi.org/10.2217/bmm-2018-0392
https://doi.org/10.2217/bmm-2018-0392
Autor:
Matcheri S. Keshavan, Gualberto Ruaño, Andreas Windemuth, Paulo Lizano, Neeraj Tandon, John A. Sweeney, Olivia Lutz, Godfrey D. Pearlson, Elliot S. Gershon, George Ling, Jaya Padmanabhan, Brett A. Clementz, Carol A. Tamminga, Mohan Kocherla
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-9 (2018)
Translational Psychiatry
Translational Psychiatry
Vascular endothelial growth factor A (VEGFA) dysfunction may contribute to a number of pathological processes that characterize psychotic disorders. However, the influence of VEGFA gene variants on clinical and neuroimaging phenotypes in psychotic di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be062ef3023118c498d5d6c4a161e8c3
http://link.springer.com/article/10.1038/s41398-018-0271-y
http://link.springer.com/article/10.1038/s41398-018-0271-y
Autor:
James S, Graydon, Karla, Claudio, Seth, Baker, Mohan, Kocherla, Mark, Ferreira, Abiel, Roche-Lima, Jovaniel, Rodríguez-Maldonado, Jorge, Duconge, Gualberto, Ruaño
Publikováno v:
Biomark Med
AIM: Variants of the MTHFR gene have been associated with a wide range of diseases. MATERIALS & METHODS: The present study analyzed data from clinical genotyping of MTHFR 677C>T and 1298A>C in 1405 patients in urban primary care settings. RESULTS: St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03b090949b6e6785fdcd87ca2da4d0d3
https://pubmed.ncbi.nlm.nih.gov/31157538
https://pubmed.ncbi.nlm.nih.gov/31157538
Autor:
Mohan Kocherla, Golriz Yazdanpanah, Richard L. Seip, Jorge Duconge, Gualberto Ruaño, Alan Hb Wu, Andreas Windemuth, Theodore R. Holford, Bruce Bower, C Michael White, David Villagra, Paul D. Thompson
Publikováno v:
Personalized medicine. 5(3)
Background: Polymorphisms in the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) genes significantly alter the effective warfarin dose. The CYP2C9*2 (430C>T), CYP2C9*3 (1075A>C) and VKORC1 -1639 G>A polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b143d766acb54aa6bb64a467361905b
https://pubmed.ncbi.nlm.nih.gov/29783498
https://pubmed.ncbi.nlm.nih.gov/29783498
Autor:
Vince D. Calhoun, Mohan Kocherla, Gualberto Ruaño, Kasey O’Neil, John A. Sweeney, Matcheri S. Keshavan, Balaji Narayanan, Godfrey D. Pearlson, Carol A. Tamminga, Sabra M. Dunn, Ian T. Mathew, Andreas Windemuth, Neeraj Tandon, Brett A. Clementz, Lauren E. Ethridge
Publikováno v:
American Journal of Psychiatry. 172:466-478
Biological risk factors underlying psychosis are poorly understood. Biological underpinnings of the dimension of psychosis can be derived using genetic associations with intermediate phenotypes such as subcomponents of auditory event-related potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae640a5f1008d505243e1490e867977b
https://doi.org/10.1176/appi.ajp.2014.13101411
https://doi.org/10.1176/appi.ajp.2014.13101411
Publikováno v:
Journal of painpalliative care pharmacotherapy. 31(2)
A 44-year-old Caucasian woman presented with a history of empirical treatment with 20 pain and psychotropic medications, as well as dual comorbidity of intractable pain and depression. A multiple gain-of-function profile in the CYP450 family of cytoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cdcf20fb278f8742a85d64fb87746c
https://pubmed.ncbi.nlm.nih.gov/28506184
https://pubmed.ncbi.nlm.nih.gov/28506184
Autor:
Pranav Nanda, Matcheri S. Keshavan, Godfrey D. Pearlson, Shashwath A. Meda, Shaun M. Eack, John A. Sweeney, Ian T. Mathew, Mohan Kocherla, Gualbert Ruaño, Neeraj Tandon, Brett A. Clementz, Carol A. Tamminga, Balaji Narayanan, Andreas Windemuth, Tracey L. Petryshen, Sarah E. Bergen, Jaya Padmanabhan
Publikováno v:
Schizophrenia research. 182
Background Schizophrenia, schizoaffective disorder, and psychotic bipolar disorder overlap with regard to symptoms, structural and functional brain abnormalities, and genetic risk factors. Neurobiological pathways connecting genes to clinical phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c15aa44ba19ef00cda4340b6c47ad9d
https://pubmed.ncbi.nlm.nih.gov/27789186
https://pubmed.ncbi.nlm.nih.gov/27789186
Autor:
Mohan Kocherla, Margaret T. Susce, John W. Goethe, Harold I. Schwartz, Gualberto Ruaño, Kali Bogaard, Andreas Windemuth, Jose de Leon, Richard L. Seip, Theodore R. Holford, Stephen B. Woolley
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 36:213-219
The purpose of this study was to identify genetic variants predictive of cardiovascular risk factors in a psychiatric population treated with second generation antipsychotics (SGA). 924 patients undergoing treatment for severe mental illness at four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd5d2ae99008db5cf1f007787abc4d9
https://doi.org/10.1016/j.pnpbp.2011.08.001
https://doi.org/10.1016/j.pnpbp.2011.08.001
Autor:
Andreas Windemuth, Gualberto Ruaño, Mohan Kocherla, John W. Goethe, David Villagra, Harold I. Schwartz, Krystyna Gorowski, Bonnie L. Szarek
Publikováno v:
Biomarkers in Medicine. 5:427-438
Aims: We aim to demonstrate clinical relevance and utility of four novel drug-metabolism indices derived from a combinatory (multigene) approach to CYP2C9, CYP2C19 and CYP2D6 allele scoring. Each index considers all three genes as complementary compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0311a5301b0edd79e3914a23be1dfad
https://doi.org/10.2217/bmm.11.32
https://doi.org/10.2217/bmm.11.32
Autor:
Gualberto Ruaño, Mohan Kocherla, David Villagra, Jane Buckley, Joan Landino, Andreas Windemuth, Krystyna Gorowski, John M. Roy
Publikováno v:
Journal of the American Academy of Nurse Practitioners. 23:459-463
Purpose: To illustrate the utility of CYP450 genotyping to guide clinical psychopharmacological treatment decisions and minimize or avoid harmful and costly adverse drug reactions (ADRs). Data sources: DNA was extracted from a whole blood sample from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69a0465894db414e5af5ac4061d80fb
https://doi.org/10.1111/j.1745-7599.2011.00640.x
https://doi.org/10.1111/j.1745-7599.2011.00640.x