Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mohan Bhadbhade"'
Autor:
Mahmoud El Safadi, Katie A. Wilson, Indigo J. Strudwicke, Megan L. O’Mara, Mohan Bhadbhade, Tristan Rawling, Andrew M. McDonagh
Publikováno v:
Molecules, Vol 29, Iss 17, p 4213 (2024)
The accumulation of iron in dopaminergic neurons can cause oxidative stress and dopaminergic neuron degeneration. Iron chelation therapy may reduce dopaminergic neurodegeneration, but chelators should be targeted towards dopaminergic cells. In this w
Externí odkaz:
https://doaj.org/article/876baac2f9e948f3a75ddf6bfdbc2528
Publikováno v:
Molecules, Vol 29, Iss 17, p 4273 (2024)
Tetrahydroquinolines are key structures in a variety of natural products with diverse pharmacological utilities and other applications. A series of 3,4-diaryl-5,7-dimethoxy-1,2,3,4-tetrahydroquinolines were synthesized in good yield by reacting 3-ary
Externí odkaz:
https://doaj.org/article/0e4d69aa9eed49a3bec7295195ab34f3
Autor:
Andrew T. King, Hugh G. Hiscocks, Lidia Matesic, Mohan Bhadbhade, Roger Bishop, Alison T. Ung
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1347-1354 (2019)
The one-pot reaction of 2,6-bis(diphenylmethyl)-4-methoxyaniline with tert-butylnitrite, BTEAC and DABSO in the presence of CuCl2 provided an unexpected 3H-indazole product 8. The structure of the compound was determined by HRMS, IR, NMR and further
Externí odkaz:
https://doaj.org/article/5749363b49d24e89b0f9811125cb766f
Autor:
Basmah Almohaywi, Tsz Tin Yu, George Iskander, Shekh Sabir, Mohan Bhadbhade, David StC. Black, Naresh Kumar
Publikováno v:
Antibiotics, Vol 11, Iss 2, p 151 (2022)
The Quorum-sensing system in Pseudomonas aeruginosa is responsible for the pathogenicity and the production of virulence factors and biofilm formation. Dihydropyrrolones were previously found to act as inhibitors of QS-dependent bacterial phenotypes.
Externí odkaz:
https://doaj.org/article/f140969dd3564e1fb30a2eef0962d63a
Publikováno v:
Molecules, Vol 26, Iss 13, p 3974 (2021)
Histone deacetylase enzymes (HDACs) are potential targets for the treatment of cancer and other diseases, but it is challenging to design isoform-selective agents. In this work, we created new analogs of two established but non-selective HDAC inhibit
Externí odkaz:
https://doaj.org/article/838aa2a1009f47e28833fcd3005337e6
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 1, Pp m14-m15 (2014)
In the title complex salt, [{(η5-C5Me5)Rh}2(μ-Cl)3]PF6, the dinuclear, single-charged cation is formed by the cojoining of two classic (η5-C5Me5)RhCl3 `piano-stool' units by bridging of the three choride ligand `legs'. The crystal structure shows
Externí odkaz:
https://doaj.org/article/b626411662da4ea4b127ae3630fe9a30
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 6, Pp o872-o873 (2013)
The title compound (systematic name: 3,7-dihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one dimethyl sulfoxide monosolvate), C15H12O5·C2H6OS, was isolated from an unidentified endophytic fungus (belonging to class Ascomycetes) of Taxus sp. In the
Externí odkaz:
https://doaj.org/article/8207b48da8294973876d67ee142e8f22
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 4, Pp m231-m231 (2013)
The title complex, {[Cu(C21H13N5S2)]PF6·CH3CN}n, was formed immediately on adding together a methanol solution containing copper(I) ions and a methanol solution of 2,6-bis[4-(pyridin-2-yl)thiazol-2-yl]pyridine. Crystallographic studies of the comple
Externí odkaz:
https://doaj.org/article/c7a4721729d54c029fb70d4adf46d894
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 1, Pp m47-m48 (2013)
The compound (μ-3,3′,3′′,3′′′-{[2,5,8,15,18,21-hexaoxatricyclo[20.4.0.09,14]hexacosa-1(22),9,11,13,23,25-hexaene-11,12,24,25-tetrayl]tetrakis(methylene)}tetrakis(1-methyl-1H-imidazol-2-yl))bis[(η4-cycloocta-1,4-diene)rhodium(I)] bis(hex
Externí odkaz:
https://doaj.org/article/6312e4a47c0a4759bff4abb1a35f8fb2
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 5, Pp o1471-o1471 (2012)
The title compound (AME; systematic name: 3,7-dihydroxy-9-methoxy-1-methyl-6H-benzo[c]chromen-6-one), C15H12O5, was isolated from an endophytic fungi Alternaria sp., from Catharanthus roseus (common name: Madagascar periwinkle). There is an intramole
Externí odkaz:
https://doaj.org/article/2208672b76034b29ba540353e36693f3