Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mohamood Adhil"'
Autor:
Ramveer Choudhary, Joanna Niska-Blakie, Mohamood Adhil, Giordano Liberi, Yathish Jagadheesh Achar, Michele Giannattasio, Marco Foiani
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112747- (2023)
Summary: Replication forks terminate at TERs and telomeres. Forks that converge or encounter transcription generate topological stress. Combining genetics, genomics, and transmission electron microscopy, we find that Rrm3hPif1 and Sen1hSenataxin heli
Externí odkaz:
https://doaj.org/article/2dcf6ec0f4454e4289a45fb4b96277f1
Autor:
Mohamood Adhil Iqbal
Custom made R and Python scripts. These data analysis tools are used in the following paper Negative supercoil at gene boundaries modulates gene topology (Yathish Jagadheesh Achar, Mohamood Adhil, Ramveer Choudhary, Nick Gilbert and Marco Foiani) htt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a57efd9b2610a56957568c2d2723d209
CNVlocator Author: Mohamood Adhil and Ramveer Choudhary Accurate CNV (Amplification and Deletion) calling by comparing test and control samples (BAM files) Required tools to run the CNV locator: python2.7, R, genomeCoverageBed, samtools Required pyth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512257be9a721b4d56e0ed7bcf8d3ffb
Publikováno v:
Achar, Y J, Adhil, M, Choudhary, R, Gilbert, N & Foiani, M 2020, ' Negative supercoil at gene boundaries modulates gene topology ', Nature, vol. 577, no. 7792, pp. 701–705 . https://doi.org/10.1038/s41586-020-1934-4
Transcription challenges the integrity of replicating chromosomes by generating topological stress and conflicts with forks1,2. The DNA topoisomerases Top1 and Top2 and the HMGB family protein Hmo1 assist DNA replication and transcription3–6. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055efb14079b4f63d1d787a7606725e3
https://hdl.handle.net/20.500.11820/0e7323f6-cbfb-4475-b8ac-3022720e5278
https://hdl.handle.net/20.500.11820/0e7323f6-cbfb-4475-b8ac-3022720e5278
Autor:
Kidiyoor, Gururaj Rao, Li, Qingsen, Bastianello, Giulia, Bruhn, Christopher, Giovannetti, Irene, Mohamood, Adhil, Beznoussenko, Galina V., Mironov, Alexandre, Raab, Matthew, Piel, Matthieu, Restuccia, Umberto, Matafora, Vittoria, Bachi, Angela, Barozzi, Sara, Parazzoli, Dario, Frittoli, Emanuela, Palamidessi, Andrea, Panciera, Tito, Piccolo, Stefano, Scita, Giorgio, Maiuri, Paolo, Havas, Kristina M., Zhou, Zhong-Wei, Kumar, Amit, Bartek, Jiri, Wang, Zhao-Qi, Foiani, Marco
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11, ⟨10.1038/s41467-020-18580-9⟩
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, Nature Publishing Group, 2020, 11, ⟨10.1038/s41467-020-18580-9⟩
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
ATR responds to mechanical stress at the nuclear envelope and mediates envelope-associated repair of aberrant topological DNA states. By combining microscopy, electron microscopic analysis, biophysical and in vivo models, we report that ATR-defective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::af55cf82bd279fbfffb6748379b73c0c
http://hdl.handle.net/11577/3445218
http://hdl.handle.net/11577/3445218
Publikováno v:
Systems Biology in Animal Production and Health, Vol. 1 ISBN: 9783319433332
Improvements in animal health, productivity, or disease resistance require an understanding of functional genomics, which can be obtained using multiscale multi-omics data analysis. Multiscale omics data analysis requires the integration of bottom-up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50bed96edba1a940b2147e2c5b463fbd
https://doi.org/10.1007/978-3-319-43335-6_6
https://doi.org/10.1007/978-3-319-43335-6_6
Publikováno v:
Big Data Analytics ISBN: 9783319270562
BDA
BDA
Cancer research is emerging as a complex orchestration of genomics, data-sciences, and network-sciences. For improving cancer diagnosis and treatment strategies, data across multiple scales, from molecules like DNA, RNA, metabolites, to the populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e17c4be2304bf7da1f17b78f98f2869
https://doi.org/10.1007/978-3-319-27057-9_16
https://doi.org/10.1007/978-3-319-27057-9_16
Autor:
Kidiyoor GR; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Li Q; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Bastianello G; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Bruhn C; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Giovannetti I; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Mohamood A; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Beznoussenko GV; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Mironov A; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Raab M; Institut Curie/CNRS, Paris, France., Piel M; Institut Curie/CNRS, Paris, France., Restuccia U; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Matafora V; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Bachi A; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Barozzi S; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Parazzoli D; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Frittoli E; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Palamidessi A; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Panciera T; University of Padova, Padova, Italy., Piccolo S; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy.; University of Padova, Padova, Italy., Scita G; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy.; University of Milan, Milan, Italy., Maiuri P; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Havas KM; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy., Zhou ZW; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; School of Medicine, Sun Yat-Sen University, Shenzhen, China., Kumar A; Genome and Cell Integrity Lab, CSIR-Indian Institute of Toxicology Research, Lucknow, India., Bartek J; Danish Cancer Society Research Center, Copenhagen, Denmark.; Karolinska Institute, Stockholm, Sweden., Wang ZQ; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; Friedrich-Schiller University, Jena, Germany., Foiani M; IFOM- FIRC Institute of Molecular Oncology, Milan, Italy. marco.foiani@ifom.eu.; University of Milan, Milan, Italy. marco.foiani@ifom.eu.
Publikováno v:
Nature communications [Nat Commun] 2020 Sep 24; Vol. 11 (1), pp. 4828. Date of Electronic Publication: 2020 Sep 24.