Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mohammed Z Haque"'
Autor:
Andrew Wu, Andrew J Eaton, Paulo Caceres, Puja Shrestha-Maskey, Indra Adrianto, Jessica Granados-Pineda, Mohammed Z Haque, Jose A Garcia Pedraza, Pablo A Ortiz
Publikováno v:
Hypertension. 79
Elevated fructose consumption is associated with hypertension in humans. In normal Sprague Dawley rats, a high fructose intake (20% fructose drinking water) induced salt sensitive hypertension. We found that fructose directly stimulates the apical Na
Publikováno v:
The FASEB Journal. 36
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0154151 (2016)
Membrane cholesterol levels play an important factor in regulating cell function. Sarcolemmal cholesterol is concentrated in lipid rafts and caveolae, which are flask-shaped invaginations of the plasma membrane. The scaffolding protein caveolin permi
Externí odkaz:
https://doaj.org/article/9b78dca4bdbe4d9aaefd45e8560a6b9c
Publikováno v:
The Journal of Biological Chemistry
Renal cells of the thick ascending limb (TAL) reabsorb NaCl via the apical Na+/K+/2Cl− co-transporter NKCC2. Trafficking of NKCC2 to the apical surface regulates NKCC2-mediated NaCl absorption and blood pressure. The molecular mechanisms by which N
Autor:
Mohammed Z Haque, Ilham Bettahi, Ramzi M. Mohammad, Abdul Badie Abou Samra, Monika S. Young, Suresh S. Palaniyandi, Vinod Kumar
Publikováno v:
The FASEB Journal. 32
Publikováno v:
American Journal of Physiology-Renal Physiology. 305:F1031-F1041
In the present study, we examine the hypothesis that the nitric oxide (NO) produced by endothelial NO synthase (eNOS) plays a protective role in the development of ANG II-induced hypertension and renal injury by minimizing oxidative stress and the in
Publikováno v:
Hypertension. 60:1464-1470
Salt-sensitive hypertension involves a renal defect preventing the kidney from eliminating excess NaCl. The thick ascending limb of Henle loop reabsorbs ≈30% of filtered NaCl via the apical Na-K-2Cl cotransporter (NKCC2). Higher NKCC2 activity and
Autor:
Mohammed Z. Haque, Dewan S. A. Majid
Publikováno v:
American Journal of Hypertension. 24:114-118
Background gp91(PHOX), a catalytic subunit of NAD(P)H oxidase, is involved in angiotensin II (Ang II)-induced superoxide (O₂⁻) generation. This study was designed to examine the hypothesis that an enhancement in O₂⁻ generation due to elevated
Autor:
Dewan S. A. Majid, Mohammed Z. Haque
Publikováno v:
American Journal of Physiology-Renal Physiology. 295:F758-F764
Both short-term and long-term nitric oxide (NO) blockade were shown to cause an increase in O2−activity. To assess the contribution of such enhanced O2−activity in the kidney, responses to administration of the NO synthase inhibitor nitro-l-argin
Publikováno v:
The FASEB Journal. 29
Fructose consumption increased in the past three decades and has been implicated in the epidemic of hypertension, diabetes and obesity. 10% of the US population consumes up to 20% of their calories...