Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mohammed Y R, Sardar"'
Autor:
Richard D. Cummings, Walter Wever, Appi Reddy Mandhapati, Dayoung Park, Mohammed Y. R. Sardar, Simon S. Park, Elliot L. Chaikof, Venkata R. Krishnamurthy
Publikováno v:
Carbohydrate Research. 452:47-53
LewisX (LeX) is a branched trisaccharide Galβ1→4(Fucα1→3)GlcNAc that is expressed on many cell surface glycoproteins and plays critical roles in innate and adaptive immune responses. However, efficient synthesis of glycopeptides bearing LeX rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344ba60a16e820449002749153db8394
https://doi.org/10.1016/j.carres.2017.10.002
https://doi.org/10.1016/j.carres.2017.10.002
Autor:
Walter Wever, Mohammed Y. R. Sardar, Richard D. Cummings, Elliot L. Chaikof, Appi Reddy Mandhapati, Simon S. Park
Publikováno v:
J Org Chem
Selectins are a class of cell adhesion molecules that play a critical role during the initial steps of inflammation. The N-terminal domain of P-selectin glycoprotein ligand-1 (PSGL-1) binds to all selectins, but with the highest affinity to P-selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f045ca232efc0678870fb1813af16444
https://europepmc.org/articles/PMC7648531/
https://europepmc.org/articles/PMC7648531/
Autor:
Tongzhong Ju, Richard D. Cummings, Mohammed Y. R. Sardar, Elliot L. Chaikof, Xiaodong Sun, Alison V. Nairn, Matthew R Kudelka, Kelley W. Moremen
Publikováno v:
Glycobiology. 28(4)
Mucin-type O-glycans decorate >80% of secretory and cell surface proteins and contribute to health and disease. However, dynamic alterations in the O-glycome are poorly understood because current O-glycomic methodologies are not sufficiently sensitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c331d83daae3130e7b3354fe1a2571c8
https://pubmed.ncbi.nlm.nih.gov/29390058
https://pubmed.ncbi.nlm.nih.gov/29390058
Autor:
Mohammed Y R, Sardar, Venkata R, Krishnamurthy, Simon, Park, Appi Reddy, Mandhapati, Walter J, Wever, Dayoung, Park, Richard D, Cummings, Elliot L, Chaikof
Publikováno v:
Carbohydrate research. 452
Lewis X (LeX) is a branched trisaccharide Galβ1→4(Fucα1→3)GlcNAc that is expressed on many cell surface glycoproteins and plays critical roles in innate and adaptive immune responses. However, efficient synthesis of glycopeptides bearing LeX re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a20f72b28aa6611e87a67129882139cf
https://pubmed.ncbi.nlm.nih.gov/29065342
https://pubmed.ncbi.nlm.nih.gov/29065342
Autor:
Robert J. Woods, Mohammed Y. R. Sardar, Xiaocong Wang, Vasilios A. Morikis, Erbin Dai, Xuezheng Song, Elliot L. Chaikof, Carolyn A. Haller, Lijun Sun, Yu Ying, Donny Hanjaya-Putra, Richard D. Cummings, Scott I. Simon, Venkata R. Krishnamurthy
Publikováno v:
Nature communications
Blockade of P-selectin (P-sel)/PSGL-1 interactions holds significant potential for treatment of disorders of innate immunity, thrombosis and cancer. Current inhibitors remain limited due to low binding affinity or by the recognized disadvantages inhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc0e33469c9037ac7af32ec2d57f9a7
http://hdl.handle.net/10379/12318
http://hdl.handle.net/10379/12318