Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mohammed T. El-Saadi"'
Publikováno v:
Analytical Methods. 15:1016-1027
Two rapid, accurate and ecofriendly chromatographic methods were developed for simultaneous determination of bendamustine, gemcitabine and vinorelbine for the purpose of an in vivo pharmacokinetics study in rats.
Publikováno v:
Chromatographia. 86:109-123
Combination therapy of gemcitabine and sorafenib is synergistically effective and well tolerated in patients with non-small cell lung cancer (NSCLC). In this study, the pharmacokinetic parameters of both gemcitabine and sorafenib were estimated after
Publikováno v:
Journal of AOAC International.
Background Gemcitabine (GEM), a pyrimidine nucleoside, has been used as a first line treatment in non-small cell lung cancer (NSCLC). Sorafenib (SOR), a non-selective multi kinase inhibitor, is used as a chemotherapeutic agent in different types of c
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 299:122836
Publikováno v:
Bioorganic Chemistry. 135:106496
Publikováno v:
Bioanalysis. 13:969-983
Aim: Green, accurate and rapid methods, namely LC–MS/MS and thin layer chromatography-densitometric methods, were developed for determination of amlodipine besylate and celecoxib in presence of its process-related impurities, 4-methylacetophenone i
Publikováno v:
Bioorganic chemistry. 121
A series of 1,2,4-triazolo[1,5-a]pyrimidine derivatives have been designed and synthesized as combretastatin CA-4 analogs. They were screened for anticancer and tubulin polymerization inhibition activities. The trimethoxyphenyl 1,2,4-triazolo[1,5-a]p
Autor:
Noha H. Amin, Mohammed I. A. Hamed, Ahmed H.A. Abusabaa, Maha M. Abdel-Fattah, Mohammed T. El-Saadi
Publikováno v:
Bioorganic chemistry. 116
Novel diarylpyrazole (5a-d, 6a-e, 12, 13, 14, 15a-c and 11a-g) derivatives were designed, synthesized and evaluated for their dual COX-2/sEH inhibitory activities via recombinant enzyme assays to explore their anti-inflammatory activities and cardiov
Publikováno v:
Future Medicinal Chemistry. 11:1871-1882
Aim: Everyday studies prove the increasing need for newer and safer agents to control cellular inflammatory response, an underlying cause for the pathophysiology of many other clinical cases. Results: Two newly designed sets of schiff 5a-h and chlaco
Publikováno v:
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 263
Five simple, selective and accurate spectrophotometric methods have been applied and developed for first time for simultaneous determination of amlodipine besylate (AML) and celecoxib (CEL) in presence of one harmful impurity, 4-methylacetophenone (M