Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mohammed T. Abdel Aal"'
Autor:
Asmaa A. Mandour, Ibrahim F. Nassar, Mohammed T. Abdel Aal, Mahmoud A. E. Shahin, Wael A. El-Sayed, Maghawry Hegazy, Amr Mohamed Yehia, Ahmed Ismail, Mohamed Hagras, Eslam B. Elkaeed, Hanan M. Refaat, Nasser S. M. Ismail
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1957-1973 (2022)
Cyclin-dependent kinase inhibition is considered a promising target for cancer treatment for its crucial role in cell cycle regulation. Pyrazolo pyrimidine derivatives were well established for their antitumor activity via CDK2 inhibition. In this re
Externí odkaz:
https://doaj.org/article/1e6ab14dd8874e4886ee7d210668ea2f
Autor:
Abdou K. Allayeh, Aliaa H. El-boghdady, Mohamed A. Said, Mahmoud G. A. Saleh, Mohammed T. Abdel-Aal, Mohamed G. Abouelenein
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 198 (2024)
The SARS-CoV-2 pandemic at the end of 2019 had major worldwide health and economic consequences. Until effective vaccination approaches were created, the healthcare sectors endured a shortage of operative treatments that might prevent the infection
Externí odkaz:
https://doaj.org/article/b5d24c7012b14147bab4579e738e6020
Autor:
Ibrahim F. Nassar, Mohammed T. Abdel Aal, Wael A. El-Sayed, Mahmoud A. E Shahin, Elsayed G. E. Elsakka, Mahmoud Mohamed Mokhtar, Maghawry Hegazy, Mohamed Hagras, Asmaa A. Mandour, Nasser S. M. Ismail
Publikováno v:
RSC Advances. 12:14865-14882
A new set of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffolds (4–13) as well as the thioglycoside derivatives (14, 15) were designed, and synthesized as novel CDK2 targeting compounds.
Autor:
Ibrahim F. Nassar, Wael A. El-Sayed, Mohammed T. Abdel Aal, Nagwan S. El Bakary, Samy A. El Assaly
Publikováno v:
Universal Journal of Pharmaceutical Research.
Background: In recent papers, it was found that 1,3,4-oxadiazole, 1,3,4-thiadiazoleand 1,2,4-triazole pharmacophores are present in several drugs, tiodazosin and nesapidil (antihypertensive), raltegravir (antiretroviral), Furamizole, cefazolin and ce
Autor:
Ibrahim F, Nassar, Mohammed T, Abdel Aal, Wael A, El-Sayed, Mahmoud, A E Shahin, Elsayed G E, Elsakka, Mahmoud Mohamed, Mokhtar, Maghawry, Hegazy, Mohamed, Hagras, Asmaa A, Mandour, Nasser S M, Ismail
Publikováno v:
RSC advances. 12(23)
CDK2 inhibition is an appealing target for cancer treatment that targets tumor cells in a selective manner. A new set of small molecules featuring the privileged pyrazolo[3,4
Publikováno v:
Chemical and Pharmaceutical Bulletin. 67:888-895
New sugar hydrazones incorporating furan and/or 1,3,4-thiadiazole ring systems were synthesized by reaction of the corresponding hydrazide with different aldose sugars. Heterocyclization of the formed hydrazones afforded the derived acyclic nucleosid
Autor:
Osama A.M. Ali, Mohammed T. Abdel-Aal
Publikováno v:
Egyptian Journal of Agronomy.
EGYPT is currently experiencing water shortage, which causes a threat to crop productivity and efficiency of water use, especially in light of the current climatic changes. A field experiment was done to study effect of irrigation intervals (12, 16 a
Autor:
Mohammed T. Abdel-Aal, Osama A.M. Ali
Publikováno v:
Egyptian Journal of Agronomy.
TWO FIELD experiments were done at Experimental Farm, Faculty of Agriculture, Menoufia University, Shebin El- Kom, Egypt, during 2018 and 2019 seasons to study the effect of 3 irrigation intervals, i.e., irrigation every 12 (I1), 17 (I2) and 22 days
Publikováno v:
Dyes and Pigments. 155:300-312
Our work has been heavily engaged in the synthesis of novel phthalocyanines with various functional groups and/or heterocycles at peripheral and axial positions via the reaction of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) with 1,4-diazabicyclo
Publikováno v:
Egyptian Journal of Agronomy. :239-249
TWO FIELD experiments were conducted at El-Sirw Agricultural Research Station, Damietta Governorate, Egypt during summer seasons of 2015 and 2016 to investigate the effect of three irrigation intervals ( 3 , 6 and 9 days ) and four soil application o