Výsledky vyhledávání - "Mohammed T, Alsaadi"

Experimentally designed chromatographic method for the simultaneous analysis of dimenhydrinate, cinnarizine and their toxic impurities

Autor: Noha H. Amin, Ahmed S. Saad, Nada S. Abdelwahab, Fadwa H. Edrees, Mohammed T. Alsaadi

Publikováno v: RSC advances. 11(3)

Recently, experimental design has beaten the traditional optimization approach (one variable at a time) by providing better quality for chromatographic separation using minimal effort and resources. Benzophenone (BZP) and [1-(diphenylmethyl)piperazin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd55053bad80c712e11985442d73af56
https://pubmed.ncbi.nlm.nih.gov/35424104

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Simultaneous estimation of dimenhydrinate, cinnarizine and their toxic impurities benzophenone and diphenylmethylpiperazine;

Autor: Nada S, Abdelwahab, Fadwa H, Edrees, Mohammed T, Alsaadi, Noha H, Amin, Ahmed S, Saad

Publikováno v: RSC advances. 10(61)

The British Pharmacopeia (BP) reported that the carcinogenic and hepatotoxic, benzophenone (BZP) is a dimenhydrinate (DMH) impurity. On the other hand, cinnarizine (CIN) is reported to have five impurities (A-E). The toxicity profile of CIN impuritie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ec00b82250a94582614e1cc1c0af4682
https://pubmed.ncbi.nlm.nih.gov/35521250

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