Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mohammed Suhail Chaudhry"'
Autor:
Mohammed Suhail Chaudhry, Jessica Spahn, Shilpen Patel, Charles S. Fuchs, Jennifer Lauchle, Nikheel Kolatkar, Nicole Richie, Quita Highsmith, Meghan McKenzie, Ruma Bhagat
Publikováno v:
Nature medicine. 28(8)
Publikováno v:
The Journal of Immunology. 198:40-46
The success of allogeneic hematopoietic stem cell transplantation, a key treatment for many disorders, is intertwined with T cell immune reconstitution. The thymus plays a key role post allogeneic hematopoietic stem cell transplantation in the genera
Autor:
Antonia, Rotolo, Valentina S, Caputo, Monika, Holubova, Nicoleta, Baxan, Olivier, Dubois, Mohammed Suhail, Chaudhry, Xiaolin, Xiao, Katerina, Goudevenou, David S, Pitcher, Kyriaki, Petevi, Carolina, Kachramanoglou, Sandra, Iles, Kikkeri, Naresh, John, Maher, Anastasios, Karadimitris
Publikováno v:
Cancer Cell
Summary Chimeric antigen receptor anti-CD19 (CAR19)-T cell immunotherapy-induced clinical remissions in CD19+ B cell lymphomas are often short lived. We tested whether CAR19-engineering of the CD1d-restricted invariant natural killer T (iNKT) cells w
Publikováno v:
Cancer Cell
Publikováno v:
The Journal of Immunology. 193:4761-4768
CD1d is a nonpolymorphic, MHC class I–like molecule that presents phospholipid and glycosphingolipid Ags to a subset of CD1d-restricted T cells called invariant NKT (iNKT) cells. This CD1d–iNKT cell axis regulates nearly all aspects of both the i
Autor:
Edward Kanfer, Donald McDonald, Aristeidis Chaidos, Scott J. Patterson, Anastasios Karadimitris, John M. Goldman, John C. Davis, Katy Rezvani, Irene Roberts, David Marin, Jane F. Apperley, Amin Rahemtulla, Jiri Pavlu, Mohammed Suhail Chaudhry, Richard Szydlo, Francesco Dazzi, Dragana Milojkovic
Publikováno v:
Blood. 119:5030-5036
Invariant natural killer T (iNKT) cells are powerful immunomodulatory cells that in mice regulate a variety of immune responses, including acute GVHD (aGVHD). However, their clinical relevance and in particular their role in clinical aGVHD are not kn
Publikováno v:
Acta Haematologica. 126:141-146
Primary lymphoma of bone is extremely rare. There are increasing reports of lymphoma arising in bone adjacent to metallic prostheses. Herein, we describe the case of a 76-year-old man who developed diffuse large B cell lymphoma in the tibia 3 years a
Autor:
Mohammed Suhail Chaudhry
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 192:1247-1248
Autor:
Anna K. Bassil, Binbin Liu, Valentina S. Caputo, Nigel J. Parr, Rab K. Prinjha, BaoChau Le, Trevor D. Chapman, Irene Roberts, Nicola Harker, Jason Witherington, Leanne Cutler, Niam Al-Mahdi, Anastasios Karadimitris, Antonia Rotolo, Nicholas Smithers, Ilaria Marigo, David F. Tough, Amin Rahemtulla, Maurits F. Kleijnen, Katerina Gouvedenou, Aristeidis Chaidos, Peter J. Tummino, Mohammed Suhail Chaudhry, Olena Barbash, Andrea C. Haynes
Publikováno v:
Blood. 123(5)
The bromodomain and extraterminal (BET) protein BRD2-4 inhibitors hold therapeutic promise in preclinical models of hematologic malignancies. However, translation of these data to molecules suitable for clinical development has yet to be accomplished
Publikováno v:
American journal of hematology. 86(5)
A 42-year-old gentleman presented with a one month history of occipital swelling, on a background of intermittent headaches over the previous 6 months. He was, otherwise, fit and well. He had suffered a head injury 2 years earlier but there was no ot