Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mohammed Naseer Ahmed Khan"'
Autor:
Mohammed Naseer Ahmed Khan, Pogula Praveen Kumar, Ahmed Kamal, Bobburi Naga Sheshadri, O. Srinivas
Publikováno v:
Letters in Drug Design & Discovery. 12:374-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4956e5423276f1ad736709d0eb962a0c
https://doi.org/10.2174/1570180811666140915221955
https://doi.org/10.2174/1570180811666140915221955
Autor:
Miki Suzuki, Takayoshi Suzuki, Daisuke Ogasawara, Hiroki Tsumoto, Yukihiro Itoh, Yosuke Ota, Mohammed Naseer Ahmed Khan, Naoki Miyata, Tamio Mizukami, Hidehiko Nakagawa
Publikováno v:
MedChemComm. 6:407-412
Lysine-specific demethylase 1 (LSD1), the first histone demethylase to be identified, catalyzes specifically the demethylation of the mono- and dimethyl groups of histone H3 lysine 4, and its dysregulation is thought to contribute to the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a19ae265d644807d3e0c01d9b2ebbf
https://doi.org/10.1039/c4md00330f
https://doi.org/10.1039/c4md00330f
Publikováno v:
Medicinal Research Reviews. 33:873-910
trans-2-Phencylcyclopropylamine (2-PCPA), a potent, clinically used antidepressant, affects monoamine neurotransmitter levels by inhibiting the main metabolizing enzymes, monoamine oxidases (MAOs). However, the antidepressant action of this compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66514ed9adb63158dc6fa065f1c67f5a
https://doi.org/10.1002/med.21269
https://doi.org/10.1002/med.21269
Publikováno v:
Medicinal research reviews. 33(4)
trans-2-Phencylcyclopropylamine (2-PCPA), a potent, clinically used antidepressant, affects monoamine neurotransmitter levels by inhibiting the main metabolizing enzymes, monoamine oxidases (MAOs). However, the antidepressant action of this compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a6448b74ea6f216c91bac05fd4f4062
https://pubmed.ncbi.nlm.nih.gov/22893613
https://pubmed.ncbi.nlm.nih.gov/22893613
Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors
Autor:
Natsuko Tokuda, Katsura Yamatsuta, Hidehiko Nakagawa, Takuya Seko, Hideyuki Sawada, Mohammed Naseer Ahmed Khan, Naoki Miyata, Yukihiro Itoh, Takayoshi Suzuki, Jun Takeuchi, Erika Imai
Publikováno v:
Journal of medicinal chemistry. 55(12)
Selective inhibitors of human sirtuin 2 (SIRT2), a deacetylase, are candidate therapeutic agents for neurodegenerative diseases such as Parkinson's disease and Huntington's disease as well as potential tools for elucidating the biological functions o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::424511625f9c97a57d7c697474cb918a
https://pubmed.ncbi.nlm.nih.gov/22642300
https://pubmed.ncbi.nlm.nih.gov/22642300
Autor:
Mohammed Naseer Ahmed Khan, Ahmed Kamal, Kokkonda Sreekanth, Bobburi Naga Seshadri, Praveen Kumar Pogula
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 9(5)
As a continuation of our efforts to develop the benzimidazole-PBD conjugates as potential anticancer agents, a series of heteroaryl substituted benzimidazole linked PBD conjugates has been synthesized and evaluated for their anticancer potential in 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daecf30ba29466cbcb5ae1951ed73c11
https://pubmed.ncbi.nlm.nih.gov/23301523
https://pubmed.ncbi.nlm.nih.gov/23301523
Autor:
Koichi Koseki, Hidehiko Nakagawa, Takayoshi Suzuki, Koshiki Mino, Daisuke Ogasawara, Makoto Hasegawa, Takuya Matsubara, Rie Ueda, Naoki Miyata, Mohammed Naseer Ahmed Khan, Ryuzo Sasaki, Tamio Mizukami
Publikováno v:
Bioorganicmedicinal chemistry. 19(12)
Optically active (1S,2R)-NCL-1 and (1R,2S)-NCL-1 were synthesized and evaluated for their lysine-specific demethylase 1 inhibitory activity and cell growth inhibitory activity. In enzyme assays, the (1S,2R)-isomer was approximately four times more po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cc2b1f26b8d648e3a8898122e5825d
https://pubmed.ncbi.nlm.nih.gov/21227703
https://pubmed.ncbi.nlm.nih.gov/21227703
Publikováno v:
Chemical biologydrug design. 73(6)
The synthesis of a series of 10-substituted 5,5-dioxo-5,10-dihydro[1,2,4]triazolo[4,3-b][1,2,4]benzothiadiazine coupled with sulfanylacetamido benzothiazole pharmacophores (5a-g) is described. All the synthesized compounds have been evaluated for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc24266010482c2e020bedb9c9d3fedb
https://pubmed.ncbi.nlm.nih.gov/19635062
https://pubmed.ncbi.nlm.nih.gov/19635062
Publikováno v:
ChemInform. 37
Substituted aryl oxiranes undergo the facile ring opening with phenols in the presence of catalytic amount of bismuth(III) triflate to afford 1,3-diaryloxy-2-propanols in excellent yields under mild conditions. Bismuth(lll) triflate is relatively non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc72453067d65d06423ef0e0acd8f42d
https://doi.org/10.1002/chin.200601090
https://doi.org/10.1002/chin.200601090
Publikováno v:
Chemistry Letters. 34:1142-1143
Substituted aryl oxiranes undergo the facile ring opening with phenols in the presence of catalytic amount of bismuth(III) triflate to afford 1,3-diaryloxy-2-propanols in excellent yields under mild conditions. Bismuth(lll) triflate is relatively non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3a8450695466e52844a238875d91b0
https://doi.org/10.1246/cl.2005.1142
https://doi.org/10.1246/cl.2005.1142