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pro vyhledávání: '"Mohammed Milham"'
Autor:
Solmaz Sahebajam, Adam B. Cohen, Varun Monga, Mohammed Milham, Surasak Phuphanich, Jeremy Rudnick, Olivier Rixe, Christopher Smith, Eugene P. Kennedy, Rimas V. Lukas, Howard Colman
Publikováno v:
Neuro Oncol
BACKGROUND Optimal management of progressive high-grade gliomas (HGG) is not fully defined and outcomes are poor. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme which converts tryptophan to kynurenines, which contribute to the immunosuppresive tum