Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mohammed M. Dar"'
Autor:
Johann de Bono, Mohammed M. Dar, C. Martin Curtis, Bo Ma, A. Benjamin Suttle, Roger E. McLendon, Jorge Barriuso, Jeffrey Raizer, Steve Rosenfeld, Tom Mikkelsen, Louis Nabors, Patrick Y. Wen, Morris D. Groves, David A. Reardon
PDF file - 82K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb8954667ce67d039a6bd7b135b18a9
https://doi.org/10.1158/1078-0432.22450127.v1
https://doi.org/10.1158/1078-0432.22450127.v1
Autor:
Johann de Bono, Mohammed M. Dar, C. Martin Curtis, Bo Ma, A. Benjamin Suttle, Roger E. McLendon, Jorge Barriuso, Jeffrey Raizer, Steve Rosenfeld, Tom Mikkelsen, Louis Nabors, Patrick Y. Wen, Morris D. Groves, David A. Reardon
PDF file - 182K, Tumor reduction in 3 patients who achieved a partial response following (A) 21 days, (B) 15 months, and (C) 18 months of treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555c9b5970fe8207a3720f2fdd5bb3a7
https://doi.org/10.1158/1078-0432.22450130.v1
https://doi.org/10.1158/1078-0432.22450130.v1
Autor:
Sarah P. Blagden, Johann S. de Bono, Richard Wilson, Mohammed M. Dar, Thomas A. Lampkin, Sharon C. Murray, Deborah A. Smith, Alicia J. Allred, Yan Y. Degenhardt, Hanine Medani, Jorge Barriuso, Anne B. Taegtmeyer, Timothy A. Yap, Andre T. Brunetto, Rohini Sharma, Douglas Barker, David Olmos
Supplementary Methods; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa656e44c9db5425b374f6954cb9ce23
https://doi.org/10.1158/1078-0432.22441227
https://doi.org/10.1158/1078-0432.22441227
Autor:
Johann de Bono, Mohammed M. Dar, C. Martin Curtis, Bo Ma, A. Benjamin Suttle, Roger E. McLendon, Jorge Barriuso, Jeffrey Raizer, Steve Rosenfeld, Tom Mikkelsen, Louis Nabors, Patrick Y. Wen, Morris D. Groves, David A. Reardon
Purpose: Increased mitogenic signaling and angiogenesis, frequently facilitated by somatic activation of EGF receptor (EGFR; ErbB1) and/or loss of PTEN, and VEGF overexpression, respectively, drive malignant glioma growth. We hypothesized that patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b869cb9e4bce5879511f2bc803cbfdf7
https://doi.org/10.1158/1078-0432.c.6521861.v1
https://doi.org/10.1158/1078-0432.c.6521861.v1
Autor:
Johann de Bono, Mohammed M. Dar, C. Martin Curtis, Bo Ma, A. Benjamin Suttle, Roger E. McLendon, Jorge Barriuso, Jeffrey Raizer, Steve Rosenfeld, Tom Mikkelsen, Louis Nabors, Patrick Y. Wen, Morris D. Groves, David A. Reardon
PDF file - 179K, Study design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521e44faacc8ce15e43853e40cc4dec2
https://doi.org/10.1158/1078-0432.22450133.v1
https://doi.org/10.1158/1078-0432.22450133.v1
Autor:
Sarah P. Blagden, Johann S. de Bono, Richard Wilson, Mohammed M. Dar, Thomas A. Lampkin, Sharon C. Murray, Deborah A. Smith, Alicia J. Allred, Yan Y. Degenhardt, Hanine Medani, Jorge Barriuso, Anne B. Taegtmeyer, Timothy A. Yap, Andre T. Brunetto, Rohini Sharma, Douglas Barker, David Olmos
Purpose: GSK461364 is an ATP-competitive inhibitor of polo-like kinase 1 (Plk1). A phase I study of two schedules of intravenous GSK461364 was conducted.Experimental Design: GSK461364 was administered in escalating doses to patients with solid malign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff23bf4b14372b8aa854f554ab505b1
https://doi.org/10.1158/1078-0432.c.6518349
https://doi.org/10.1158/1078-0432.c.6518349
Autor:
Diwakar Davar, Shannon Marshall, Melissa Lynne Johnson, Rodolfo Gutierrez, Mohammed M. Dar, Neil H. Segal, George R. Blumenschein
Publikováno v:
Journal of Clinical Oncology. 38:TPS3165-TPS3165
TPS3165 Background: ImmTAC bispecifics are unique T cell receptor (TCR)/anti-CD3 bispecific molecules that are designed to redirect polyclonal T cells against intracellular antigens, in contrast to antibody-based therapies, which are limited to extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f3ee39839d85133c222240d23944d0
https://doi.org/10.1200/jco.2020.38.15_suppl.tps3165
https://doi.org/10.1200/jco.2020.38.15_suppl.tps3165
Autor:
Mohammed M. Dar, Paul Wheatley-Price, George R. Blumenschein, Shirish M. Gadgeel, Xia Li, Toshiaki Takahashi
Publikováno v:
Clinical lung cancer. 20(3)
Introduction Platinum doublet chemotherapy has represented the standard of care in advanced non–small-cell lung cancer for decades. Targeting platelet-derived growth factor receptors (PDGFR) is a potential mechanism to improve the efficacy of first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fca4c56ee0f6858dd5162d4564e4e5
https://pubmed.ncbi.nlm.nih.gov/30685114
https://pubmed.ncbi.nlm.nih.gov/30685114
Autor:
Leanne Cartee, Hyun Choel Chung, Mohammed M. Dar, Jane Holshouser White, Yung-Jue Bang, Kevin M. Koch, Jeff Botbyl, Nikita Arya, Quincy Chu, Jennifer Beyer, Linda P. Briley, Deborah A. Smith
Publikováno v:
Clinical Pharmacology in Drug Development. 4:449-453
The potential for an interaction between lapatinib and absorption of the P-glycoprotein (ABCB1) substrate digoxin at a therapeutic dose in breast cancer patients was characterized. Seventeen women with HER2-positive metastatic breast cancer received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c57b60523d1c346dea77ec2121d0d2bd
https://doi.org/10.1002/cpdd.189
https://doi.org/10.1002/cpdd.189
Autor:
Marja Mergui-Roelvink, Jan H.M. Schellens, Hyun Choel Chung, Yung-Jue Bang, Lionel D. Lewis, Mohammed M. Dar, Jos H. Beijnen, Deborah A. Smith, Alwin D. R. Huitema, Emile E. Voest, Petronella O. Witteveen, David S. Mendelson, Lot A. Devriese
Publikováno v:
British Journal of Clinical Pharmacology. 80:253-266
Aims The aim of the study was to determine the effect of renal impairment and prior platinum-based chemotherapy on the toxicity and pharmacokinetics of oral topotecan and to identify recommended doses for patients with renal impairment or prior plati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d229e2607e6a988264bb42724d4ee533
https://doi.org/10.1111/bcp.12606
https://doi.org/10.1111/bcp.12606