Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mohammed M. Al Qaraghuli"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The structures of the Fc base of various IgG antibodies have been examined with a view to understanding how this region can be used to conjugate IgG to nanoparticles. The base structure is found to be largely consistent across a range of spe
Externí odkaz:
https://doaj.org/article/ef239524ae0b4060a8497467731b4148
Autor:
Ahmed A. Abdulhussein Al-Ali PhD, Nameer Al Ward MSc, Mohammad A. Obeid PhD, Carsten Uhd Nielsen PhD, Paul A. Mulheran PhD, Mohammed M. Al Qaraghuli PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Recently, much research is focused on the use of photothermal therapy (PTT) as an advanced method to treat various types of cancer. The PTT approach primarily utilizes nanoparticles (NPs) made from metals, carbon, or semiconductors that can convert n
Externí odkaz:
https://doaj.org/article/c777213a2cf64e19be65733729514b9c
Autor:
Mohammed A. H. Farouq, Reinaldo Acevedo, Valerie A. Ferro, Paul A. Mulheran, Mohammed M. Al Qaraghuli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6078 (2022)
Antibodies play a crucial role in the immune response, in fighting off pathogens as well as helping create strong immunological memory. Antibody-dependent enhancement (ADE) occurs when non-neutralising antibodies recognise and bind to a pathogen, but
Externí odkaz:
https://doaj.org/article/e299d18c3cc741cabd1e583a9ab20917
Autor:
Mohammed A. H. Farouq, Karina Kubiak-Ossowska, Mohammed M. Al Qaraghuli, Valerie A. Ferro, Paul A. Mulheran
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4832 (2022)
Staphylococcus protein A (SpA) is found in the cell wall of Staphylococcus aureus bacteria. Its ability to bind to the constant Fc regions of antibodies means it is useful for antibody extraction, and further integration with inorganic materials can
Externí odkaz:
https://doaj.org/article/7def18df693e47639e4f7134d21c3a48
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Antibodies are well known for their high specificity that has enabled them to be of significant use in both therapeutic and diagnostic applications. Antibodies can recognize different antigens, including proteins, carbohydrates, peptides, nucleic aci
Externí odkaz:
https://doaj.org/article/b7cbf6c641b141e8ba31d276066e6fbc
Autor:
Mohammed M. Al Qaraghuli
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Head and neck cancer (HNC) is a heterogeneous disease that includes a variety of tumors originating in the hypopharynx, oropharynx, lip, oral cavity, nasopharynx, or larynx. HNC is the sixth most common malignancy worldwide and affects thousands of p
Externí odkaz:
https://doaj.org/article/6575f013deb343d8be2cedad58a08847
Publikováno v:
Antibodies, Vol 7, Iss 3, p 21 (2018)
Monoclonal antibodies (mAbs) have revolutionized the biomedical field, directly influencing therapeutics and diagnostics in the biopharmaceutical industry, while continuing advances in computational efficiency have enabled molecular dynamics (MD) sim
Externí odkaz:
https://doaj.org/article/c7616e8f66934b9f9cb628506eab7baa
Autor:
null Ahmed A. Abdulhussein Al-Ali, null Nameer Al Ward, null Mohammad A. Obeid, null Carsten Uhd Nielsen, null Paul A. Mulheran, null Mohammed M. Al Qaraghuli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba038612367c8c1c5fbe16069f1bb7c
https://doi.org/10.1177/15330338231168016/v2/response1
https://doi.org/10.1177/15330338231168016/v2/response1
Autor:
Paul A. Mulheran, Mohammed M. Al Qaraghuli, Karina Kubiak-Ossowska, Valerie A. Ferro, Neret Pujol-Navarro, Elpiniki Paspali, Gillian A. Horne, Mark Williams, Richard Soutar, Manal Alsaadi
Publikováno v:
Therapeutic delivery. 12(10)
Multiple myeloma is the second most common hematological malignancy in adults, accounting for 2% of all cancer-related deaths in the UK. Current chemotherapy-based regimes are insufficient, as most patients relapse and develop therapy resistance. Thi
Autor:
Mohammed M. Al Qaraghuli, Karina Kubiak-Ossowska, Valerie A. Ferro, Paul A. Mulheran, Mohammed A.H. Farouq
Nanoparticles are small particles sized 1–100 nm, which have a large surface-to-volume ratio, allowing efficient adsorption of drugs, proteins, and other chemical compounds. Consequently, functionalized nanoparticles have potential diagnostic and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5167d234f4929a1be67ea6798489dcd
https://strathprints.strath.ac.uk/76238/1/Farouq_etal_2021_COCIS_2021_Biomolecular_interactions_with_nanoparticles_applications.pdf
https://strathprints.strath.ac.uk/76238/1/Farouq_etal_2021_COCIS_2021_Biomolecular_interactions_with_nanoparticles_applications.pdf