Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mohammed K. Abdel-Hamid"'
Autor:
Peter J. Cossar, Mohammed K. Abdel-Hamid, Cong Ma, Jennette A. Sakoff, Trieu N. Trinh, Christopher P. Gordon, Peter J. Lewis, Adam McCluskey
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3839-3857 (2017)
Externí odkaz:
https://doaj.org/article/18507ec09c4e43c9ac4c112c6de0fa28
Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo
Autor:
Alireza Shakoori, John B. Bremner, Mohammed K. Abdel-Hamid, Anthony C. Willis, Rachada Haritakun, Paul A. Keller
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 481-492 (2015)
Diversity-directed synthesis based on the cascade allylation chemistry of indigo, with its embedded 2,2’-diindolic core, has resulted in rapid access to new examples of the hydroxy-8a,13-dihydroazepino[1,2-a:3,4-b']diindol-14(8H)-one skeleton in up
Externí odkaz:
https://doaj.org/article/12956ff9b5d9428eb84fd0fc028478c9
Publikováno v:
Molecules, Vol 19, Iss 5, Pp 6609-6622 (2014)
Clathrin-mediated endocytosis (CME) is a process that regulates selective internalization of important cellular cargo using clathrin-coated vesicles. Perturbation of this process has been linked to many diseases including cancer and neurodegenerative
Externí odkaz:
https://doaj.org/article/565245f4e07045e2883374bb5c1c92d7
Autor:
Jane Thanassi, Michael J. Pucci, Tarek Aboul-Fadl, Hatem A. Abdel-Aziz, Tilal Elsaman, Mohammed K. Abdel-Hamid
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 7864-7879 (2011)
In the present study a series of Schiff bases of indoline-2,3-dione were synthesized and investigated for their Mtb gyrase inhibitory activity. Promising inhibitory activity was demonstrated with some of these derivatives, which exhibited IC50 values
Externí odkaz:
https://doaj.org/article/2df55134361b45d589e949f80406bf13
Akademický článek
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Autor:
Mahmoud A. El Hassab, Mohamed Fares, Mohammed K. Abdel-Hamid Amin, Sara T. Al-Rashood, Amal Alharbi, Razan O. Eskandrani, Hamad M. Alkahtani, Wagdy M. Eldehna
Publikováno v:
Processes
Volume 9
Issue 6
Processes, Vol 9, Iss 1004, p 1004 (2021)
Volume 9
Issue 6
Processes, Vol 9, Iss 1004, p 1004 (2021)
Since December 2019, the world has been facing the outbreak of the SARS-CoV-2 pandemic that has infected more than 149 million and killed 3.1 million people by 27 April 2021, according to WHO statistics. Safety measures and precautions taken by many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce31c7afd2f52c349f4ef95df8d2cd3c
https://hdl.handle.net/2123/25588
https://hdl.handle.net/2123/25588
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Mohammed K. Abdel-Hamid, Christopher P. Gordon, Trieu N. Trinh, Peter J. Lewis, Jennette A. Sakoff, Adam McCluskey, Peter J. Cossar, Cong Ma
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3839-3857 (2017)
ACS Omega
ACS Omega
The NusB–NusE protein–protein interaction (PPI) is critical to the formation of stable antitermination complexes required for stable RNA transcription in all bacteria. This PPI is an emerging antibacterial drug target. Pharmacophore-based screeni
Autor:
Jennette A. Sakoff, Eileen A. McLaughlin, Christopher P. Gordon, V. Pye, Peter J. Cossar, Mohammed K. Abdel-Hamid, Ilana R. Bernstein, Adam McCluskey, Trieu N. Trinh
Publikováno v:
Organic & Biomolecular Chemistry. 14:6304-6315
A series of quinolone-2-(1H)-ones derived from the Ugi-Knoevenagel three- and four-component reaction were prepared exhibiting low micromolar cytotoxicity against a panel of eight human cancer cell lines known to possess the Hedgehog Signalling Pathw
Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo
Autor:
John B. Bremner, Mohammed K. Abdel-Hamid, Rachada Haritakun, Paul A. Keller, Alireza Shakoori, Anthony C. Willis
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 481-492 (2015)
Beilstein Journal of Organic Chemistry, Vol 11, Iss 1, Pp 481-492 (2015)
Diversity-directed synthesis based on the cascade allylation chemistry of indigo, with its embedded 2,2’-diindolic core, has resulted in rapid access to new examples of the hydroxy-8a,13-dihydroazepino[1,2-a:3,4-b']diindol-14(8H)-one skeleton in up