Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mohammed H. Sayegh"'
Autor:
Hilde-Kari Guttormsen, Anne Karin Brigtsen, Anil Chandraker, Arlene H. Sharpe, Dennis L. Kasper, Mohammed H. Sayegh
Publikováno v:
Infection and Immunity. 67:6375-6384
Covalent linkage of a bacterial polysaccharide to an immunogenic protein greatly enhances the carbohydrate's immunogenicity and induces polysaccharide-specific B-cell memory in vivo. These findings have spurred the development of glycoconjugate vacci
Autor:
Milan S. Blake, Fiona G. Mackinnon, Mohammed H. Sayegh, Yu Ho, Francis Michon, Anil Chandraker, Lee M. Wetzler
Publikováno v:
The Journal of Infectious Diseases. 180:755-761
A T cell-dependent immune response to group C meningococcal capsular polysaccharide (CPS) can be elicited when CPS is conjugated to the class 3 neisserial porin (CPS-porin). Treatment of CPS-porin-immunized mice with B7-2 blocking monoclonal antibody
Autor:
Mohammed H. Sayegh, Asim Saha, Bruce R. Blazar, Brent H. Koehn, Gordon J. Freeman, Brian T. Fife, Hideo Yagita, Rafi Ahmed, Miyuki Azuma, Angela Panoskaltsis-Mortari, Arlene H. Sharpe, William J. Murphy, David H. Munn, Rachelle G. Veenstra, Kazutoshi Aoyama, Nader Najafian, Patricia A. Taylor, Gérard Socié
Publikováno v:
Blood. 122(17)
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, play an important role in the maintenance of peripheral tolerance. We explored the role of PD-1 ligands in regulating graft-versus-host disease (GVHD). Both PD-L1 and PD-L2 expression were u
Autor:
Koichi Shimizu, Akira Yamada, Didier A. Mandelbrot, Richard N. Mitchell, Arlene H. Sharpe, Gordon J. Freeman, Mohammed H. Sayegh, Mariëtte A. Oosterwegel
Publikováno v:
The Journal of clinical investigation. 107(7)
To examine whether B7 costimulation can be mediated by a molecule on T cells that is neither CD28 nor CTLA4, we generated mice lacking both of these receptors. CD28/CTLA4(-/-) mice resemble CD28(-/-) mice in having decreased expression of T-cell acti