Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mohammed H. Cherkaoui‐Rbati"'
Autor:
Mohammed H. Cherkaoui‐Rbati, Nicole Andenmatten, Lydia Burgert, Oluwaseun F. Egbelowo, Rolf Fendel, Chiara Fornari, Michael Gabel, John Ward, Jörg J. Möhrle, Nathalie Gobeau
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 1, Pp 50-61 (2023)
Abstract Chemoprophylactics are a vital tool in the fight against malaria. They can be used to protect populations at risk, such as children younger than the age of 5 in areas of seasonal malaria transmission or pregnant women. Currently approved che
Externí odkaz:
https://doaj.org/article/91245b38753741cfa2057e092803c40e
Autor:
Yeka Adoke, Rella Zoleko-Manego, Serge Ouoba, Alfred B. Tiono, Grace Kaguthi, Juvêncio Eduardo Bonzela, Tran Thanh Duong, Alain Nahum, Marielle Bouyou-Akotet, Bernhards Ogutu, Alphonse Ouedraogo, Fiona Macintyre, Andreas Jessel, Bart Laurijssens, Mohammed H. Cherkaoui-Rbati, Cathy Cantalloube, Anne Claire Marrast, Raphaël Bejuit, David White, Timothy N. C. Wells, Florian Wartha, Didier Leroy, Afizi Kibuuka, Ghyslain Mombo-Ngoma, Daouda Ouattara, Irène Mugenya, Bui Quang Phuc, Francis Bohissou, Denise P. Mawili-Mboumba, Fredrick Olewe, Issiaka Soulama, Halidou Tinto, the FALCI Study Group
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-25 (2021)
Abstract Background For uncomplicated Plasmodium falciparum malaria, highly efficacious single-dose treatments are expected to increase compliance and improve treatment outcomes, and thereby may slow the development of resistance. The efficacy and sa
Externí odkaz:
https://doaj.org/article/9984adbb71374f0b9bb2d7ec8eac47cd
Autor:
Annabelle Walz, Maëlle Duffey, Ghaith Aljayyoussi, Sibylle Sax, Didier Leroy, Dominique Besson, Jeremy N. Burrows, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Marie-Anne Westwood, Christoph Siethoff, Francisco-Javier Gamo, Pascal Mäser, Sergio Wittlin
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 163 (2023)
With artemisinin-resistant Plasmodium falciparum parasites emerging in Africa, the need for new antimalarial chemotypes is persistently high. The ideal pharmacodynamic parameters of a candidate drug are a rapid onset of action and a fast rate of para
Externí odkaz:
https://doaj.org/article/ed61e47142b2471096b9a830abacea17
Autor:
Sebastian G, Wicha, Annabelle, Walz, Mohammed H, Cherkaoui-Rbati, Nils, Bundgaard, Karsten, Kuritz, Christin, Gumpp, Nathalie, Gobeau, Jörg, Möhrle, Matthias, Rottmann, Claudia, Demarta-Gatsi
Publikováno v:
Antimicrobial agents and chemotherapy. 66(11)
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69ca47eb5dd435a7253d3e965c4376a1
https://pubmed.ncbi.nlm.nih.gov/36197116
https://pubmed.ncbi.nlm.nih.gov/36197116
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183794 (2017)
All pharmaceutical companies are required to assess pharmacokinetic drug-drug interactions (DDIs) of new chemical entities (NCEs) and mathematical prediction helps to select the best NCE candidate with regard to adverse effects resulting from a DDI b
Externí odkaz:
https://doaj.org/article/3f862c1b716a4db4b4e4d54729e47fae
Autor:
Mohammed H. Cherkaoui‐Rbati, Nicole Andenmatten, Lydia Burgert, Oluwaseun F. Egbelowo, Rolf Fendel, Chiara Fornari, Michael Gabel, John Ward, Jörg J. Möhrle, Nathalie Gobeau
Publikováno v:
CPT: pharmacometricssystems pharmacologyREFERENCES.
Chemoprophylactics are a vital tool in the fight against malaria. They can be used to protect populations at risk, such as children younger than the age of 5 in areas of seasonal malaria transmission or pregnant women. Currently approved chemoprophyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aafa92052639bed8fff16eeb025cd9c
https://pubmed.ncbi.nlm.nih.gov/36412499
https://pubmed.ncbi.nlm.nih.gov/36412499
Autor:
Georges F R, Radohery, Annabelle, Walz, Christin, Gumpp, Mohammed H, Cherkaoui-Rbati, Nathalie, Gobeau, Jeremy, Gower, Miles P, Davenport, Matthias, Rottmann, James S, McCarthy, Jörg J, Möhrle, Maria, Rebelo, Claudia, Demarta-Gatsi, David S, Khoury
Publikováno v:
Antimicrobial agents and chemotherapy. 66(7)
The rate at which parasitemia declines in a host after treatment with an antimalarial drug is a major metric for assessment of antimalarial drug activity in preclinical models and in early clinical trials. However, this metric does not distinguish be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d56d2aa024836e01382caa998b78541
https://pubmed.ncbi.nlm.nih.gov/35727057
https://pubmed.ncbi.nlm.nih.gov/35727057
Autor:
Sebastian G. Wicha, Annabelle Walz, Mohammed H. Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi
The development and spread of drug resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4207f08f0ab8650dc4f78b285258737
https://doi.org/10.1101/2022.04.19.488858
https://doi.org/10.1101/2022.04.19.488858
Autor:
Sebastian G. Wicha, Annabelle Walz, Mohammed H. Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51aa13cc6c34f92d37762808071bd8b0
Autor:
Georges F. R. Radohery, Annabelle Walz, Christin Gumpp, Mohammed H. Cherkaoui-Rbati, Nathalie Gobeau, Jeremy Gower, Miles P. Davenport, Matthias Rottmann, James S. McCarthy, Jörg J. Möhrle, Maria Rebelo, Claudia Demarta-Gatsi, David S. Khoury
The rate at which parasitemia declines in a host after treatment with an antimalarial drug is a major metric for assessment of antimalarial drug activity in preclinical models and in early clinical trials. However, this metric does not distinguish be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1814a75e43518a8968e14d2be8b932b
https://edoc.unibas.ch/90789/
https://edoc.unibas.ch/90789/