Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mohammed Farhoud"'
Autor:
Dustin A Deming, Alyssa A Leystra, Mohammed Farhoud, Laura Nettekoven, Linda Clipson, Dawn Albrecht, Mary Kay Washington, Ruth Sullivan, Jamey P Weichert, Richard B Halberg
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60709 (2013)
The phosphatidylinositide-3-kinase (PI3K) signaling pathway is critical for multiple cellular functions including metabolism, proliferation, angiogenesis, and apoptosis, and is the most commonly altered pathway in human cancers. Recently, we develope
Externí odkaz:
https://doaj.org/article/d31eff1ed832492ba8863e2f9091656e
Autor:
Daniel J Kelley, Mohammed Farhoud, M Elizabeth Meyerand, David L Nelson, Lincoln F Ramirez, Robert J Dempsey, Alan J Wolf, Andrew L Alexander, Richard J Davidson
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1119 (2007)
The human brain and skull are three dimensional (3D) anatomical structures with complex surfaces. However, medical images are often two dimensional (2D) and provide incomplete visualization of structural morphology. To overcome this loss in dimension
Externí odkaz:
https://doaj.org/article/5a2bc0bc2b9c4ed09ef0ee2ec3e842eb
Autor:
Shil Patel, Karl F. Schmidt, Mohammed Farhoud, Tong Zi, Su Chul Jang, Kevin Dooley, Dustin Kentala, Howard Dobson, Kyriakos Economides, Douglas E. Williams
Publikováno v:
Nuclear Medicine and Biology. :20-30
Autor:
Richard B. Halberg, Jamey P. Weichert, Jose R. Torrealba, Mary Kay Washington, Ruth Sullivan, Linda Clipson, Dawn M. Albrecht, Laura A. Nettekoven, Jamie N. Hadac, Terrah J. Paul Olson, Mohammed Farhoud, Christopher D. Zahm, Dustin A. Deming, Alyssa A. Leystra
WMP file - 834MB, The tumors in FC+ PIK3ca*+ mice exhibit high avidity for 124I-CLR1404. A mouse was injected with the imaging agent and then dual hybrid PET/CT colonography was performed. The agent was detected in all three tumors. This mouse is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85e94d2d295c5c321e30e9ffb8f9357
https://doi.org/10.1158/0008-5472.22393131
https://doi.org/10.1158/0008-5472.22393131
Autor:
Richard B. Halberg, Jamey P. Weichert, Jose R. Torrealba, Mary Kay Washington, Ruth Sullivan, Linda Clipson, Dawn M. Albrecht, Laura A. Nettekoven, Jamie N. Hadac, Terrah J. Paul Olson, Mohammed Farhoud, Christopher D. Zahm, Dustin A. Deming, Alyssa A. Leystra
PDF file - 583K, Mice expressing activated PI3K were scanned to identify those bearing tumors. After sacrifice, the intestine was removed to characterize tissue morphology, cell signaling and cell proliferation within the epithelium and the associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8e1d05f86abde0c7fd774a6a9ae190
https://doi.org/10.1158/0008-5472.22393134.v1
https://doi.org/10.1158/0008-5472.22393134.v1
Autor:
Shil, Patel, Karl F, Schmidt, Mohammed, Farhoud, Tong, Zi, Su Chul, Jang, Kevin, Dooley, Dustin, Kentala, Howard, Dobson, Kyriakos, Economides, Douglas E, Williams
Publikováno v:
Nuclear medicine and biology.
Extracellular vesicles (EVs) have garnered increasing interest as delivery vehicles for multiple classes of therapeutics based on their role as mediators in an important, natural intercellular communication system. We recently described a platform to
Autor:
Dmitri Simberg, Kristine Glunde, Natalie J. Serkova, Ralph P. Mason, Mohammed Farhoud, Alexandra de Lille, David C. Westerly, Lynn Griffin, Chad R. Haney, Elizabeth F. Redente
Publikováno v:
Cancer Res
In animal models of cancer, oncologic imaging has evolved from a simple assessment of tumor location and size to sophisticated multimodality exploration of molecular, physiologic, genetic, immunologic, and biochemical events at microscopic to macrosc
Autor:
Kyle I. Swanson, Jamey P. Weichert, Mohammed Farhoud, Ray R. Zhang, Irawati Kandela, John S. Kuo, Paul A. Clark
Publikováno v:
Neurosurgery. 76:115-124
BACKGROUND 5-Aminolevulinic acid (5-ALA)-induced tumor fluorescence aids brain tumor resections but is not approved for routine use in the United States. We developed and describe testing of 2 novel fluorescent, cancer-selective alkylphosphocholine a
Autor:
Mohammed Farhoud, Todd E. Barnhart, Jogeshwar Mukherjee, Patrick J. Lao, Ansel T. Hillmer, Bradley T. Christian, Andrew T. Higgins, Dustin Wooten
Publikováno v:
Synapse. 67:882-886
ase inhibitors; physostigmine; galanthamine ABSTRACT Acetylcholinesterase inhibitors (AChEIs) are drugs that increase syn- aptic acetylcholine (ACh) concentrations and are under investigation as treatments for symptoms accompanying Alzheimer's diseas
Autor:
Jogeshwar Mukherjee, Todd E. Barnhart, Bradley T. Christian, Ansel T. Hillmer, Mohammed Farhoud, Dustin Wooten
Publikováno v:
Journal of Neuroscience Methods. 214:163-169
Lobeline is a potential smoking cessation drug with affinity for the α4β2 nicotinic acetylcholine receptor and may inhibit the blood–brain barrier (BBB) amine transporter. The goal of this work was to use PET imaging to evaluate the effects of lo