Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mohammed Diksin"'
Autor:
Joshua Branter, Maria Estevez-Cebrero, Mohammed Diksin, Michaela Griffin, Marcos Castellanos-Uribe, Sean May, Ruman Rahman, Richard Grundy, Surajit Basu, Stuart Smith
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 1982 (2022)
The lack of treatment options for high-grade brain tumors has led to searches for alternative therapeutic modalities. Electrical field therapy is one such area. The Optune™ system is an FDA-approved novel device that delivers continuous alternating
Externí odkaz:
https://doaj.org/article/a892aff8db5e4c4080049d905839d451
Autor:
Stuart J. Smith, Mohammed Diksin, Saachi Chhaya, Shwetha Sairam, Maria A. Estevez-Cebrero, Ruman Rahman
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2452 (2017)
Glioblastoma, a WHO grade IV astrocytoma, is a highly aggressive and heterogeneous tumour that infiltrates deeply into surrounding brain parenchyma, making complete surgical resection impossible. Despite chemo-radiotherapy, the residual cell populati
Externí odkaz:
https://doaj.org/article/95a18507945b4ad09106d3f8cae66f78
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2342 (2017)
Gliomas are devastating brain cancers that have poor prognostic outcomes for their patients. Short overall patient survival is due to a lack of durable, efficacious treatment options. Such therapeutic difficulties exist, in part, due to several gliom
Externí odkaz:
https://doaj.org/article/7bd3ed2c0407442fa30d05b852ce97c4
Publikováno v:
Neuro-Oncology. 24:vii298-vii298
INTRODUCTION Childhood medulloblastoma (MB) and atypical teratoid/rhabdoid tumours (AT/RT) are malignant brain tumours occurring in the posterior fossa, for which prognoses remains particularly poor for the MB Group 3 subtype characterised by amplifi
Autor:
James Wood, Salah Abdelrazig, Sergey Evseev, Catherine Ortori, Marcos Castellanos-Uribe, Sean T. May, David A. Barrett, Mohammed Diksin, Sajib Chakraborty, Dong-Hyun Kim, Richard G. Grundy, Ruman Rahman
Publikováno v:
Cancers; Volume 14; Issue 16; Pages: 3873
Poor outcomes associated with diffuse high-grade gliomas occur in both adults and children, despite substantial progress made in the molecular characterisation of the disease. Targeting the metabolic requirements of cancer cells represents an alterna
Autor:
Anbarasu Lourdusamy, Katie Wood, Stuart Smith, A.A. Ritchie, David Onion, Philip A. Clarke, Ruman Rahman, Richard Grundy, Jonathan Rowlinson, Mohammed Diksin, Maria de los Angeles Estevez-Cebrero
Publikováno v:
Neuro-oncology Advances
Background Glioblastoma (GBM) is a highly aggressive brain tumor with rapid subclonal diversification, harboring molecular abnormalities that vary temporospatially, a contributor to therapy resistance. Fluorescence-guided neurosurgical resection util
Autor:
Omar Ahmad, David J. Scurr, Christopher Gell, Tim Constantin-Teodosiu, Chris Denning, Jonathan Rowlinson, Nicola Croxall, Stuart Smith, Ruman Rahman, Jaime Hughes, David Onion, Alexander Kondrashov, Mohammed Diksin, Wei Cui
Publikováno v:
Neuro Oncol
Glioblastoma therapeutic challenges are in considerable part due to myriad survival mechanisms which allow malignant cells to repurpose signalling pathways within discreet microenvironments. These Darwinian adaptations facilitate invasion into brain
Autor:
Christopher Gell, Wei Cui, Tim Constantin-Teodo, Stuart Smith, Alexandar Kondrashov, Jamie Hughes, Nicola Croxall, David Onion, Ruman Rahman, Jonathan Rowlinson, Mohammed Diksin, Chris Denning
Publikováno v:
Neuro Oncol
Glioblastoma therapeutic challenges are in considerable part due to myriad survival adaptations and mechanisms, which allow malignant cells to repurpose signalling pathways within discreet microenvironments. These Darwinian adaptations facilitate inv