Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mohammed Dasser"'
Autor:
Annie Michaud, Mélanie Bolduc, Jérôme Bergeron, Nicholas Pelchat, Robert Chênevert, Pierre Morin, Mohammed Dasser
Publikováno v:
Tetrahedron: Asymmetry. 23:428-433
2-Substituted glycerol derivatives 4a–g were resolved by acylation with vinyl butyrate in the presence of lipases in organic media. The reverse reaction, the enzymatic hydrolysis of the corresponding butyrates 5a–g , was also highly stereoselecti
Publikováno v:
Tetrahedron: Asymmetry. 19:1333-1338
The enzymatic desymmetrization of various meso-N-Boc-2,5-cis-disubstituted pyrrolidines and pyrrolines compounds by ester hydrolysis or transesterification provided the corresponding monoesters in high enantiomeric excess.
Publikováno v:
Tetrahedron: Asymmetry. 15:1889-1892
Phosphonotrixin is a herbicidal antibiotic characterized by a unique structure bearing a C–P bond on an isoprene unit. The formal enantioselective synthesis of ( S )-(−)-phosphonotrixin (ee = 93%) in nine steps and 12% overall yield from 1,3-dihy
Autor:
Pourashraf Mehrnaz, Russell C. Mauger, Steve Wesolowski, Phillip D Edwards, Simon Sydserff, Carine Lévesque, Maxime Tremblay, Thierry Groblewski, Vijayaratnam Santhakumar, Lois Ann Lazor, Bernstein Peter Robert, James Folmer, Pascall Giguère, William Potts, Denis Labrecque, Scott Throner, Joseph Cacciola, Mark Sylvester, Mohammed Dasser, Clay W Scott, Dean G. Brown, Andrew Griffin
Publikováno v:
Journal of medicinal chemistry. 57(3)
A new series of potent and selective histamine-3 receptor (H3R) antagonists was identified on the basis of an azaspiro[2.5]octane carboxamide scaffold. Many scaffold modifications were largely tolerated, resulting in nanomolar-potent compounds in the
Autor:
Mohammed Dasser, Robert Chênevert
Publikováno v:
Canadian Journal of Chemistry. 78:275-279
Syringolide 2, a bacterial signal molecule which elicits active defence in resistant plants, has been synthesized in 9 steps from 2,3:4,5-di-O-isopropylidene-D-arabinose, a known derivative of D-arabinose.Key words: syringolide, arabinose, synthesis.
Publikováno v:
Tetrahedron: Asymmetry. 10:3117-3122
The stereoselective acylation of meso piperidines 3a , b by vinyl acetate (solvent and acyl donor) in the presence of Candida antarctica lipase gave the corresponding (2 S ,6 R ) and (2 S ,4 R ,6 R ) monoesters 2a , b in high enantiomeric purity. (5
Publikováno v:
Canadian Journal of Chemistry. 75:68-73
The C-3—C-9 main fragment of aspicilin was prepared via a fructose 1,6-diphosphate aldolase reaction. The same fragment was also synthesized by chemical transformation starting from D-arabinose. Key words: aldolase, aspicilin, arabinose, synthesis.
Publikováno v:
ChemInform. 28
The C-3—C-9 main fragment of aspicilin was prepared via a fructose 1,6-diphosphate aldolase reaction. The same fragment was also synthesized by chemical transformation starting from D-arabinose. Key words: aldolase, aspicilin, arabinose, synthesis.
Publikováno v:
ChemInform. 30
Enterolactone, a lignan isolated from biological fluids of animals and humans, was synthesized via enzymatic desymmetrization of 2-(3-methoxybenzyl)-1,3-propanediol.Key words: enterolactone, synthe...
Publikováno v:
ChemInform. 31
The stereoselective acylation of meso piperidines 3a , b by vinyl acetate (solvent and acyl donor) in the presence of Candida antarctica lipase gave the corresponding (2 S ,6 R ) and (2 S ,4 R ,6 R ) monoesters 2a , b in high enantiomeric purity. (5