Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mohammed Amir Husain"'
Autor:
Inès Khatir, Marie A. Brunet, Anna Meller, Florent Amiot, Tushar Patel, Xavier Lapointe, Jessica Avila Lopez, Noé Guilloy, Anne Castonguay, Mohammed Amir Husain, Joannie St. Germain, François-Michel Boisvert, Mélanie Plourde, Xavier Roucou, Benoit Laurent
Publikováno v:
Cells, Vol 12, Iss 4, p 615 (2023)
During aging, changes in gene expression are associated with a decline in physical and cognitive abilities. Here, we investigate the connection between changes in mRNA and protein expression in the brain by comparing the transcriptome and proteome of
Externí odkaz:
https://doaj.org/article/9312e8b607074cec916f35ae901a7537
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations. One risk factor for developing AD is the APOE gene coding for the apolipoprotein E prot
Externí odkaz:
https://doaj.org/article/e48b9531fa054c6dbf1d37a18d85521a
Autor:
Sayeed Ur Rehman, Zahid Yaseen, Mohammed Amir Husain, Tarique Sarwar, Hassan Mubarak Ishqi, Mohammad Tabish
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93913 (2014)
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. Elucidating the binding between small molecules and DNA provides great help in understanding drug-DNA interactions and in designing of new and promisin
Externí odkaz:
https://doaj.org/article/5bf67f72443846908f941af90a592eba
Autor:
Janani Balakrishnan, Mohammed Amir Husain, Annick Vachon, Raphaël Chouinard-Watkins, Pauline Léveillé, Mélanie Plourde
Publikováno v:
Nutrition and Healthy Aging. 7:147-158
BACKGROUND: Omega-3 fatty acid (OM3) intake is associated with a lower risk of developing Alzheimer’s disease, but individuals carrying the ɛ4 allele of apolipoprotein E (APOE4) might not benefit from this prevention strategy. Indeed, they might h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a313138bdfbcb20285f1ffe957897db6
https://doi.org/10.3233/nha-220169
https://doi.org/10.3233/nha-220169
Autor:
Abhishek Guha, Mohammed Amir Husain, Ying Si, L. Burt Nabors, Natalia Filippova, Grace Promer, Reed Smith, Peter H. King
Publikováno v:
Glia. 71:485-508
A major hallmark of neuroinflammation is the activation of microglia and astrocytes with the induction of inflammatory mediators such as IL-1β, TNF-α, iNOS, and IL-6. Neuroinflammation contributes to disease progression in a plethora of neurologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106211795c3a6f56dd755a1c07f0016a
https://doi.org/10.1002/glia.24288
https://doi.org/10.1002/glia.24288
Autor:
Viktoriia Bavykina, Mariano Avino, Mohammed Amir Husain, Adrien Zimmer, Hugo Parent-Roberge, Abdelouahed Khalil, Marie A. Brunet, Tamas Fülöp, Benoit Laurent
BackgroundAlzheimer’s disease (AD) is the most common form of dementia with the symptoms gradually worsening over the years. However, the driving pathological processes occur well before the appearance of symptoms. AD patients display signs of syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc55f05166500dc9150047ba2d9774c
https://doi.org/10.1101/2023.02.28.530459
https://doi.org/10.1101/2023.02.28.530459
Autor:
Mohammed Amir Husain, Annick Vachon, Raphael Chouinard-Watkins, Milène Vandal, Frédéric Calon, Mélanie Plourde
Publikováno v:
The Journal of Nutritional Biochemistry. 111:109181
The metabolism of docosahexaenoic acid (DHA), an omega-3 fatty acid, is different in carriers of APOE4, the main genetic risk factor for late-onset Alzheimer's disease. The brain relies on the plasma DHA pool for its need, but the plasma-liver-brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8207692f99f474c22391a5b2ee1cbe
https://doi.org/10.1016/j.jnutbio.2022.109181
https://doi.org/10.1016/j.jnutbio.2022.109181
Autor:
Hassan Mubarak Ishqi, Sayeed Ur Rehman, Mohammed Amir Husain, Tarique Sarwar, Mohammad Tabish
Publikováno v:
Molecular Biology Reports. 45:699-711
MYD88 is an adaptor protein known to involve in activation of NF-κB through IL-1 receptor and TLR stimulation. It consists of N-terminal death domain and C-terminal Toll/IL-R homology domain that mediates its interaction with IL-1R associated kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bbf57a346b5fcf5b66eca56f2bb85d
https://doi.org/10.1007/s11033-018-4209-5
https://doi.org/10.1007/s11033-018-4209-5
Autor:
Abad Ali, Shumaila Afrin, Mohammed Amir Husain, Shamsuzzaman, Tarique Sarwar, Mohammad Tabish, Yusra Rahman
Publikováno v:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 186:66-75
Ticlopidine is an anti-platelet drug which belongs to the thienopyridine structural family and exerts its effect by functioning as an ADP receptor inhibitor. Ticlopidine inhibits the expression of TarO gene in S. aureus and may provide protection aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f322ce3a3228cfd79cd105eb6a9993c
https://doi.org/10.1016/j.saa.2017.05.073
https://doi.org/10.1016/j.saa.2017.05.073
Autor:
Tarique Sarwar, Abad Ali, Shumaila Afrin, Mohammad Tabish, Mohammed Amir Husain, Yusra Rahman, Shamsuzzaman
Publikováno v:
Archives of Biochemistry and Biophysics. :1-12
Pirenzepine is an anti-ulcer agent which belongs to the anti-cholinergic group of gastrointestinal disorder drugs and functions as an M1 receptor selective antagonist. Drug-DNA interaction studies are of great significance as it helps in the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016070ab5279529e435158f47625c98b
https://doi.org/10.1016/j.abb.2017.05.014
https://doi.org/10.1016/j.abb.2017.05.014