Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Mohammed Al-Helal"'
1
Oral Cysts Aetiology, Classification And Treatment
Autor: Abbas Al Mkenah *, Seraj Al Baik , Mohammed Al Helal , Fulwah Alsaleem , Abdullah Al Aethan , Muntasir Aynusah , Razan Alekhmimi , Ziyad Alharbi , Sarah Alanazi , Majed Alqahtani
Oral cysts are commonly seen by patients at outpatients' clinics, and because of their heterogeneity, it is essential for dentists to be well oriented to their types and classification. Many classification systems exist for oral cysts. They can be cl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdd25b5fdfc7eddecb2a94afed16695
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3
Perceived Barriers to Breast Cancer Screening among Saudi Women at Primary Care Setting
Autor: Shaimaa Baher, Abdel-Aziz, Tarek Tawfik, Amin, Mohammed Baqir, Al-Gadeeb, Abdullah I, Alhassar, Ali, Al-Ramadan, Mohammed, Al-Helal, Mohammad, Bu-Mejdad, Lubna Abdulaziz, Al-Hamad, Eman Hussain, Alkhalaf
Publikováno v: Asian Pacific Journal of Cancer Prevention : APJCP
Background: Screening for breast cancer (BC) is of low rate in Saudi Arabia; although it is provided in the country free of charge to the population. This cross-sectional study aimed at investigating the perceived barriers towards BC screening in Al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1428bb26a0d93d553666baca7f9f1c83
https://pubmed.ncbi.nlm.nih.gov/28950697
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4
The development of quinoloneesters as novel antimalarial agents targeting the Plasmodium falciparum bc1protein complex
Autor: Robin Cowley, Nicholas Fisher, Raman Sharma, Alison E. Shone, Suet C. Leung, Neil G. Berry, Alexandre S. Lawrenson, Giancarlo A. Biagini, Paul O´Neill, Mohammed Al-Helal, Stephen A. Ward
Publikováno v: Med. Chem. Commun.. 3:39-44
Using the Gould-Jacobs methodology a small array of 6- and 7-substituted quinolones have been prepared. Analogues in the 7-series express activity as low as 0.46 nM versus Plasmodium falciparum malaria parasites and docking studies performed in silic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62b9a649fa8481a09c286a1429fa0363
https://doi.org/10.1039/c1md00183c
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7
HDQ, a Potent Inhibitor of Plasmodium falciparum Proliferation, Binds to the Quinone Reduction Site of the Cytochrome bc 1 Complex
Autor: Brigitte Meunier, Thomas Antoine, Mohammed Al-Helal, Nicholas Fisher, Alexandre S. Lawrenson, Paul A. Stocks, Cindy Vallières, Neil G. Berry, Stephen A. Ward, Giancarlo A. Biagini, Paul M. O'Neill
Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2012, 56 (7), pp.3739-3747. ⟨10.1128/AAC.00486-12⟩
The mitochondrial bc 1 complex is a multisubunit enzyme that catalyzes the transfer of electrons from ubiquinol to cytochrome c coupled to the vectorial translocation of protons across the inner mitochondrial membrane. The complex contains two distin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a128a8e22997af9a02b80a413c89d7
https://hal.archives-ouvertes.fr/hal-03470770
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8
Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression
Autor: Hilary Ranson, Giancarlo A. Biagini, Thomas Antoine, Ashley J. Warman, Stephen A. Ward, Alexandre S. Lawrenson, Roslaini Abd Majid, Paul M. O'Neill, Mohammed Al-Helal, David J. Johnson, Nicholas Fisher
Publikováno v: The Journal of Biological Chemistry
Background: Cytochrome b mutations confer atovaquone resistance, resulting in antimalarial drug failures. Results: Mutation Y268S reduces bc1 catalytic turnover and stability. Conclusion: Reduction of catalytic turnover and iron-sulfur protein conten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5439280a5aa0953d1ffc23010d93189b
https://pubmed.ncbi.nlm.nih.gov/22282497
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9
Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite
Autor: Nicholas Fisher, Giancarlo A. Biagini, Stephen A. Ward, Lu-Yun Lian, Abd Majid Roslaini, Patrick G. Bray, Mohammed Al-Helal
Publikováno v: Malaria Journal, Vol 8, Iss 1, p 38 (2009)
Malaria Journal
Background Malaria is a global health emergency, and yet our understanding of the energy metabolism of the principle causative agent of this devastating disease, Plasmodium falciparum, remains rather basic. Glucose was shown to be an essential nutrit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333ce9c3b536f87959d43959f968e21f
https://doi.org/10.1186/1475-2875-8-38
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10
Akademický článek
Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite.
Autor: Lu-Yun Lian1 lylian1@liv.ac.uk, Al-Helal, Mohammed2 alhelal@liv.ac.uk, Roslaini, Abd Majid2 doss1107@liv.ac.uk, Fisher, Nicholas2 n.e.fisher@liv.ac.uk, Bray, Patrick G.2 pgbray@liv.ac.uk, Ward, Stephen A.2 saward@liv.ac.uk, Biagini, Giancarlo A.2 Biagini@liv.ac.uk
Publikováno v: Malaria Journal. 2009, Vol. 8, p1-4. 4p. 1 Graph.
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