Zobrazeno 1 - 10
of 629
pro vyhledávání: '"Mohammed Akhter"'
Autor:
Md. Shahadat Hossain, Md. Siddik Alom, Mohammad Salauddin Kader, Mohammed Akhter Hossain, Mohammad A. Halim
Publikováno v:
ACS Physical Chemistry Au, Vol 4, Iss 5, Pp 464-475 (2024)
Externí odkaz:
https://doaj.org/article/1c446e7a97e242bc97b7c286efbbaf04
Autor:
Md. Rayhan Ali, Shahin Mahmud, Md. Omar Faruque, Md. Imam Hossain, Mohammed Akhter Hossain, K.M. Kaderi Kibria
Publikováno v:
Vaccine: X, Vol 18, Iss , Pp 100493- (2024)
Background: Shigellosis is one of the significant causes of diarrhea in Bangladesh. It is a global health problem; approximately 1.3 million people die yearly from Shigellosis. The current treatment method, using different antibiotics against Shigell
Externí odkaz:
https://doaj.org/article/3cfa8d8a88a942b1bb7ca520c980c783
Autor:
Sarah J. Piper, Giuseppe Deganutti, Jessica Lu, Peishen Zhao, Yi-Lynn Liang, Yao Lu, Madeleine M. Fletcher, Mohammed Akhter Hossain, Arthur Christopoulos, Christopher A. Reynolds, Radostin Danev, Patrick M. Sexton, Denise Wootten
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Previously, peptide selectivity in the VPAC receptor family of GPCRs was poorly understood. Here, authors combine cryo-EM and MD data to understand binding and selectivity of VPAC1R and PAC1R peptide agonists that can guide future drug development.
Externí odkaz:
https://doaj.org/article/f2ad6a82f21b446eaee66d37613979d6
Autor:
Bruce Lin, Andrew Hung, William Singleton, Kevion K. Darmawan, Rachael Moses, Bicheng Yao, Hongkang Wu, Anders Barlow, Marc‐Antoine Sani, Alastair J. Sloan, Mohammed Akhter Hossain, John D. Wade, Yuning Hong, Neil M. O'Brien‐Simpson, Wenyi Li
Publikováno v:
Aggregate, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Antimicrobial peptides (AMPs) are potentially powerful alternatives to conventional antibiotics in combating multidrug resistance, given their broad spectrum of activity. They mainly interact with cell membranes through surface electrostatic
Externí odkaz:
https://doaj.org/article/f6f052e528584d6eabb539cbf923298f
Autor:
Thomas N. G. Handley, Wenyi Li, Nicholas G. Welch, Neil M. O’Brien-Simpson, Mohammed Akhter Hossain, John D. Wade
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The day is rapidly approaching where current antibiotic therapies will no longer be effective due to the development of multi-drug resistant bacteria. Antimicrobial peptides (AMPs) are a promising class of therapeutic agents which have the potential
Externí odkaz:
https://doaj.org/article/d9505a7e8b3e4fe38ad839a14565df63
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Peptides and proteins are attractive targets for therapeutic drug development due to their exquisite target specificity and low toxicity profiles. However, their complex structures give rise to several challenges including solubility, stability, aggr
Externí odkaz:
https://doaj.org/article/94cfc8ffb32c44deb37a2ce5ae823133
Autor:
Nicholas G. Welch, Wenyi Li, Mohammed Akhter Hossain, Frances Separovic, Neil M. O'Brien-Simpson, John D. Wade
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
As we rapidly approach a post-antibiotic era in which multi-drug resistant bacteria are ever-pervasive, antimicrobial peptides (AMPs) represent a promising class of compounds to help address this global issue. AMPs are best-known for their membrane-d
Externí odkaz:
https://doaj.org/article/e2f383382858415189c0f4e55537a345
Autor:
Teja Devarakonda, Adolfo G. Mauro, Geronimo Guzman, Sahak Hovsepian, Chad Cain, Anindita Das, Praveen Praveen, Mohammed Akhter Hossain, Fadi N. Salloum
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
Background Human relaxin‐2 is a peptide hormone capable of pleiotropic effects in several organ systems. Its recombinant formulation (serelaxin) has been demonstrated to reduce infarct size and prevent excessive scar formation in animal models of c
Externí odkaz:
https://doaj.org/article/904c7aee36104b12923b5c9f653126c3
Autor:
Michela L. Mitchell, Mohammed Akhter Hossain, Feng Lin, Ernesto L. Pinheiro-Junior, Steve Peigneur, Dorothy C. C. Wai, Carlie Delaine, Andrew J. Blyth, Briony E. Forbes, Jan Tytgat, John D. Wade, Raymond S. Norton
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1785 (2021)
The role of insulin and insulin-like peptides (ILPs) in vertebrate animals is well studied. Numerous ILPs are also found in invertebrates, although there is uncertainty as to the function and role of many of these peptides. We have identified transcr
Externí odkaz:
https://doaj.org/article/18bdbcc0ae714f3885b622b15d450f3c
Autor:
Shoni Bruell, Ashish Sethi, Nicholas Smith, Daniel J. Scott, Mohammed Akhter Hossain, Qing-Ping Wu, Zhan-Yun Guo, Emma J. Petrie, Paul R. Gooley, Ross A. D. Bathgate
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Relaxin family peptide receptor 2 (RXFP2) is a GPCR known for its role in reproductive function. It is structurally related to the human relaxin receptor RXFP1 and can be activated by human gene-2 (H2) relaxin as well as its cognate ligand i
Externí odkaz:
https://doaj.org/article/8eaad5d63dd34da1a869adfafa703bc1