Multitargeted docking approach reveals droxidopa against DNA replication and repair-related protein of cervical cancer

Autor: Ahad Amer Alsaiari, Fawaz M. Almufarriji, Ali Hazazi, Daniyah A. Almarghalani, Maha Mahfouz Bakhuraysah, Amani A. Alrehaili, Shatha M. Algethami, Khulood A. Almehmadi, Fayez Saeed Bahwerth, Mohammed Ageeli Hakami

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)

Abstract Cervical cancer begins in the cells lining the cervix and is caused by persistent infection with certain types of human papillomavirus (HPV). Initially, it has no symptoms, and later it causes pelvic pain, abnormal vaginal bleeding, and pain

Externí odkaz: https://doaj.org/article/5ef780b016ee417d8d24fab0b4429d1f

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Demographics of Cauda Equina Syndrome: A Population Based Incidence Study

Autor: Julie, Woodfield, Simon, Lammy, Aimun Ab, Jamjoom, Mohammed Ag, Fadelalla, Phillip C, Copley, Mohit, Arora, Stella A, Glasmacher, Mohamed, Abdelsadg, Gabrielle, Scicluna, Michael Tc, Poon, Savva, Pronin, Andraay Hc, Leung, Stacey, Darwish, Andreas K, Demetriades, Jennifer, Brown, Niall, Eames, Patrick Fx, Statham, Ingrid, Hoeritzauer

Publikováno v: Woodfield, J, Lammy, S, Jamjoom, A A, Fadelalla, M A, Copley, P C, Arora, M, Glasmacher, S A, Abdelsadg, M, Scicluna, G, Poon, M T, Pronin, S, Leung, A H, Darwish, S, Demetriades, A K, Brown, J, Eames, N, Statham, P F & Hoeritzauer, I 2022, ' Demographics of Cauda Equina Syndrome : A Population Based Incidence Study ', Neuroepidemiology . https://doi.org/10.1159/000527727

Introduction: Cauda equina syndrome (CES) has significant medical, social, and legal consequences. Understanding the number of people presenting with CES and their demographic features is essential for planning healthcare services to ensure timely an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ec328435629235342fe74f6f35eba8
https://pubmed.ncbi.nlm.nih.gov/36315989

Modeling and forecasting biogas production from anaerobic digestion process for sustainable resource energy recovery

Autor: Miriam Mihi, Badr Ouhammou, Mohammed Aggour, Brahim Daouchi, Soufyane Naaim, El Mahdi El Mers, Tarik Kousksou

Publikováno v: Heliyon, Vol 10, Iss 19, Pp e38472- (2024)

Anaerobic digestion (AD) is one of the most extensively accepted processes for organic waste cleanup, and production of both bioenergy and organic fertilizer. Numerous mathematical models have been conceived for modeling the anaerobic process.In this

Externí odkaz: https://doaj.org/article/d45ff2f59ea542f59c766c71d0d81298

Identification of novel NLRP3 inhibitors as therapeutic options for epilepsy by machine learning-based virtual screening, molecular docking and biomolecular simulation studies

Autor: Maryam Zulfat, Mohammed Ageeli Hakami, Ali Hazazi, Arif Mahmood, Asaad Khalid, Roaya S. Alqurashi, Ashraf N. Abdalla, Junjian Hu, Abdul Wadood, Xiaoyun Huang

Publikováno v: Heliyon, Vol 10, Iss 15, Pp e34410- (2024)

The NOD-Like Receptor Protein-3 (NLRP3) inflammasome is a key therapeutic target for the treatment of epilepsy and has been reported to regulate inflammation in several neurological diseases. In this study, a machine learning-based virtual screening

Externí odkaz: https://doaj.org/article/4435d2c0624a45a78043c06bb427b1ba