Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mohammed A. M. Massoud"'
Publikováno v:
ACS Omega, Vol 8, Iss 29, Pp 26012-26034 (2023)
Externí odkaz:
https://doaj.org/article/c4b8071db7214f3fbbfb572e371e71a0
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 4 (2022)
Thiazolopyrimidines are well known to be designed to act as bio-isosteric analogues of purine nucleus. They proved to show a wide range of biological activities, such as anticancer, anti-inflammatory, antifungal, antiviral and antitubercular activity
Externí odkaz:
https://doaj.org/article/fad49e72fe5d4f64ab7d9776536bfc42
Publikováno v:
Magnetochemistry, Vol 3, Iss 4, p 41 (2017)
A series of diverse substituted 5-methyl-isoxazole-4-carboxylic acid amides, imide and esters in which the benzene ring is mono or disubstituted was prepared. Spectroscopic and conformational examination was investigated and a new insight involving s
Externí odkaz:
https://doaj.org/article/1d5ae058568a4b76b6e695be2d358e8f
Autor:
Basem Mansour, Waleed A. Bayoumi, Magda A. El‐Sayed, Laila A. Abouzeid, Mohammed A. M. Massoud
Publikováno v:
Chemical biologydrug designREFERENCES. 100(1)
Quinolines have a weighty effect as anticancer agents and 1,4-DHPs have demonstrated efficacy as anticancer agents in several studies, as well. New hybrid models of symmetric and asymmetric 1,4-DHPs and pyridines linked at C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9976c957a376f2c0ae8fdf170f7ac21c
https://pubmed.ncbi.nlm.nih.gov/35501997
https://pubmed.ncbi.nlm.nih.gov/35501997
Publikováno v:
Letters in Drug Design & Discovery. 16:273-283
Background: Quinoline scaffold acts as “privileged structure” for anticancer drug design. Certain derivatives showed good results through different mechanisms as topoisomerase 1 and kinase inhibition. Methods: A new series of 2-chloro-3-(2-amino-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6950996b99246825da96a85717a40f76
https://doi.org/10.2174/1570180815666180604090924
https://doi.org/10.2174/1570180815666180604090924
Autor:
Basem Mansour, Amira Taman, Nora E. Saleh, Mohammed A. M. Massoud, Mona Younis Youssef, Samar M. Alhusseiny, Samar N. El-Beshbishi
Publikováno v:
Journal of Helminthology. 94
Schistosomiasis represents a public health problem and praziquantel is the only drug used for treatment of all forms of the disease. Thus, the development of new anti-schistosomal agents is of utmost importance to increase the effectiveness, reduce s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd60ead6668347b73b1059fda85bac8
https://doi.org/10.1017/s0022149x2000005x
https://doi.org/10.1017/s0022149x2000005x
Autor:
Basem Mansour, Morkos A. Henen, Mohammed A. M. Massoud, Magda A.-A. El-Sayed, Waleed A. Bayoumi
Publikováno v:
Journal of Molecular Structure. 1246:131151
2-Amino-4-(2-chloroquinolin-3-yl)-7-hydroxy-4H-chromene-3-carbonitrile (3a) is a quinoline derivative that has been shown to possess antitumor activity. Beside activity, the compound has reasonable solubility in aqueous buffers. Herein, we tested its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec095d851aa9bdf69f4dc23377d46f0a
https://doi.org/10.1016/j.molstruc.2021.131151
https://doi.org/10.1016/j.molstruc.2021.131151
Autor:
Nora E. Saleh, Mona Younis Youssef, Wafaa M. El-Zayady, Samar M. Alhusseiny, Basem Mansour, Amira Taman, Mohammed A. M. Massoud, Ayat A. Elblihy
Publikováno v:
Experimental parasitology. 215
Schistosomiasis is still a public health problem. Praziquantel is the only drug available for treatment of all forms of human schistosomiasis. Although praziquantel is an effective drug against all species of human schistosomes, concerns about resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9863b9dca289240b5acc6e80b908e3f8
https://pubmed.ncbi.nlm.nih.gov/32525006
https://pubmed.ncbi.nlm.nih.gov/32525006
Autor:
Amany S. Mostafa, Abdelrahman Hamdi, Gilles Dujardin, Mathieu Y. Laurent, Khalid B. Selim, Mohammed A. M. Massoud, Annie Hémon-Ribaud
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2019, 75 (3), pp.429-440. ⟨10.1016/j.tet.2018.12.019⟩
Tetrahedron, Elsevier, 2019, 75 (3), pp.429-440. ⟨10.1016/j.tet.2018.12.019⟩
The asymmetric access to unreported trans 4-quinolinoxy oxaproline precursors is investigated here in a comparative way by 1,3-dipolar cycloaddition of vinyloxy quinolines with chiral α-alkoxycarbonyl aldonitrones and chiral cyclic surrogates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9aeeeaf05c636ccb35d9ed72e86d926
https://hal-univ-lemans.archives-ouvertes.fr/hal-02435143
https://hal-univ-lemans.archives-ouvertes.fr/hal-02435143
Publikováno v:
Archiv der Pharmazie. 352(7)
New quinolines substituted with various heterocycles and chalcone moieties were synthesized and evaluated as antitumor agents. All the synthesized compounds were in vitro screened against 60 human cancer cell lines. Compound 13 showed the highest cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014b5e4adb222d0e9fc388e465fa6fd8
https://pubmed.ncbi.nlm.nih.gov/31081954
https://pubmed.ncbi.nlm.nih.gov/31081954