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The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling

Autor: Andenæs, Kine, Lunde, Ida Gjervold, Mohammadzadeh, Naiyereh, Dahl, Christen Peder, Aronsen, Jan Magnus, Strand, Mari Elen, Palmero, Sheryl, Sjaastad, Ivar, Christensen, Geir Arve, Engebretsen, Kristin V Thunheim, Tønnessen, Theis

Publikováno v: Andenæs, Kine Lunde, Ida Gjervold Mohammadzadeh, Naiyereh Dahl, Christen Peder Aronsen, Jan Magnus Strand, Mari Elen Palmero, Sheryl Sjaastad, Ivar Christensen, Geir Arve Engebretsen, Kristin V Thunheim Tønnessen, Theis . The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. PLoS ONE. 2018, 13(7), 1-20
PLoS ONE

Externí odkaz: http://hdl.handle.net/10852/68232
https://www.duo.uio.no/bitstream/handle/10852/68232/2/file69494.pdf

The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.

Autor: Mohammadzadeh N; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Lunde IG; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway.; Center for Molecular Medicine Norway, Oslo University Hospital and University of Oslo, Oslo, Norway.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Andenæs K; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Strand ME; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Aronsen JM; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; Bjørknes College, Oslo, Norway., Skrbic B; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway.; Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway., Marstein HS; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Bandlien C; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway.; Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway., Nygård S; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway.; Department of Informatics, University of Oslo, Oslo, Norway., Gorham J; Department of Genetics, Harvard Medical School, Boston, MA, USA., Sjaastad I; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Chakravarti S; Department of Medicine, Johns Hopkins University, Baltimore, PhD, USA.; Department of Ophthalmology and Pathology, NYU Langone Health, Alexandria Life Sciences Center, West Tower, New York, NY, NY10011, USA., Christensen G; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway., Engebretsen KVT; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway.; Department of Surgery, Vestre Viken Hospital, Drammen, Norway., Tønnessen T; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway. theis.tonnessen@medisin.uio.no.; KG Jebsen Center for Cardiac Research, University of Oslo and Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway. theis.tonnessen@medisin.uio.no.; Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway. theis.tonnessen@medisin.uio.no.

Publikováno v: Scientific reports [Sci Rep] 2019 Jun 24; Vol. 9 (1), pp. 9206. Date of Electronic Publication: 2019 Jun 24.