Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mohammad Tabrizifard"'
Autor:
Luis Alejandro Zúñiga, Torben Leßmann, Karan Uppal, Nicola Bisek, Enping Hong, Caroline E. Rasmussen, Jens-Jakob Karlsson, Joachim Zettler, Lars Holten-Andersen, Kathy Bang, Dhruv Thakar, Yu-Chi Lee, Salomon Martinez, Simran Singh Sabharwal, Sebastian Stark, Frank Faltinger, Oliver Kracker, Samuel Weisbrod, Robin Müller, Tobias Voigt, Kornelia Bigott, Mohammad Tabrizifard, Vibeke Miller Breinholt, Amer M. Mirza, David B. Rosen, Kennett Sprogøe, Juha Punnonen
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Intratumoral (IT) delivery of toll-like receptor (TLR) agonists has shown encouraging anti-tumor benefit in preclinical and early clinical studies. However, IT delivery of TLR agonists may lead to rapid effusion from the tumor mic
Externí odkaz:
https://doaj.org/article/9c07ff8778c14891ac4c75977cba6fba
Autor:
Svetlana Antonenko, Grigori Ermakov, Larry Jin Wang, Mohammed Shameem, Alexandre Ambrogelly, Shuli Zhang, Ying Zhang, Liming Liu, Daisy Richardson, Mohammad Tabrizifard, Xiaoyu Yang, Fengqiang Wang, Yi Wei Zhang, Maribel Beaumont, Derek Wiswell
Publikováno v:
Journal of Pharmaceutical Sciences. 104:4002-4014
IgG4 antibodies are evolving as an important class of cancer immunotherapies. However, human IgG4 can undergo Fab arm (half molecule) exchange with other IgG4 molecules in vivo. The hinge modification by a point mutation (S228P) prevents half molecul